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Eva Kassi and Athanasios G Papavassiliou

glucose concentration ( Kämpe et al . 1989 ), posing a role of decarboxylation process in insulin secretion. Bone and energy metabolism cross talk It has recently been verified that a hormone regulating energy metabolism, leptin, through binding to its

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Holly M Johnson, Erin Stanfield, Grace J Campbell, Erica E Eberl, Gregory J Cooney and Kim S Bell-Anderson

, absorption or metabolism of glucose. To further isolate the critical location of the ingested glucose signal, we performed the experiments again and included a group of high-fat-fed rats that received a glucose infusion directly into the portal vein the

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L Zhao, Z Li, M Kullin, L A H Borg and F A Karlsson

et al. 1999 ). The increased uptake of glucose caused by diazoxide would, however, be expected to increase B-cell glucose metabolism. Probably, an unchanged glucose oxidation in spite of an increased net glucose uptake reflects a lower requirement

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Stephan Pinheiro Frankenfeld, Leonardo Pires de Oliveira, Daniele Leão Ignacio, Raquel Guimarães Coelho, Mariana Nigro Mattos, Andrea Claudia Freitas Ferreira, Denise Pires Carvalho and Rodrigo Soares Fortunato

glucose metabolism, the effects of supraphysiological doses (SDs) of anabolic–androgenic steroids on glucose metabolism are scarce. It is well-known that women with polycystic ovarian syndrome, who have hyperandrogenism, might present hyperinsulinemia with

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Corinne Caillaud, Mie Mechta, Heidi Ainge, Andreas N Madsen, Patricia Ruell, Emilie Mas, Catherine Bisbal, Jacques Mercier, Stephen Twigg, Trevor A Mori, David Simar and Romain Barrès

as a regulator involved in glucose metabolism. Results of early studies carried out of patients with end-stage renal disease (ESRD) indicated that EPO not only treated anemia but also improved insulin sensitivity ( Borissova et al . 1993 , Mak 1996

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Li Li, Xiaohua Li, Wenjun Zhou and Joseph L Messina

phosphorylation of IR substrates (IRSs) and the activation of cytosolic proteins, including phosphatidylinositol 3-kinase (PI3K). Activated PI3K phosphorylates/activates its substrates involved in glucose metabolism, such as glycogen synthase kinase-3 and p70 S6

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Makiko Shimodahira, Shimpei Fujimoto, Eri Mukai, Yasuhiko Nakamura, Yuichi Nishi, Mayumi Sasaki, Yuichi Sato, Hiroki Sato, Masaya Hosokawa, Kazuaki Nagashima, Yutaka Seino and Nobuya Inagaki

glucose metabolism regulates exocytosis of insulin granules according to metabolism-secretion coupling in which glucose-induced mitochondrial ATP production plays an essential role ( Maechler & Wollheim 2001 ). Since depletion of mitochondrial DNA

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Toya M Albury-Warren, Veethika Pandey, Lina P Spinel, Michal M Masternak and Deborah A Altomare

), respectively ( Hemmings & Restuccia 2012 ). AKT hyperactivation in various cancers has been studied ( Altomare & Testa 2005 , Cheung & Testa 2013 ), while its role in glucose metabolism has been noted but comparatively overlooked until analysis of AKT isoform

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Kunihisa Hamano, Yuko Nakagawa, Yoshiaki Ohtsu, Longfei Li, Johan Medina, Yuji Tanaka, Katsuyoshi Masuda, Mitsuhisa Komatsu and Itaru Kojima

activated by glucose, and promotes metabolism of fuels in β-cells leading to an increase in ATP ( Nakagawa et al . 2014 ). Since knockdown of T1R3 attenuates glucose-induced elevation of intracellular ATP ([ATP] c ), the glucose-sensing receptor T1R3 is