Search Results

You are looking at 51 - 60 of 109 items for :

  • "cardiac hypertrophy" x
Clear All
Free access

Daniel Landau, Chen Chayat, Nili Zucker, Eli Golomb, Channa Yagil, Yoram Yagil and Yael Segev

cardiac hypertrophy in transgenic animal models . Methods in Molecular Medicine 112 339 – 352 . Boluyt MO Long X Eschenhagen T Mende U Schmitz W Crow MT Lakatta EG 1995 Isoproterenol infusion induces alterations in expression of hypertrophy

Free access

Cássio M Villicev, Fatima R S Freitas, Marcelo S Aoki, Cássio Taffarel, Thomas S Scanlan, Anselmo S Moriscot, Miriam O Ribeiro, Antonio C Bianco and Cecília H A Gouveia

×T3 resulted in cardiac hypertrophy, characterised by an increase in the dry mass of the heart (33 and 46% vs control respectively), while GC-1 treatment had no effect. Discussion The present study shows that treatment

Free access

Rebecca M Reynolds and Adrienne Gordon

not completely understood, data from animal models, support a causal relationship between in utero exposure to maternal obesity and pathological left ventricular cardiac hypertrophy, hypertension and impaired systolic and diastolic function in the

Free access

Natasha N Chattergoon

Gloss B Swanson EA Dillmann WH 2007 Adeno-associated virus-mediated expression of thyroid hormone receptor isoforms-alpha1 and -beta1 improves contractile function in pressure overload-induced cardiac hypertrophy . Endocrinology 148

Free access

Stefan Groeneweg, Robin P Peeters, Theo J Visser and W Edward Visser

is efficiently taken up by rat cardiomyocytes ( Medina-Gomez et al. 2008 ), but is a less potent regulator of TH target genes in the heart than T 3 ( Liang et al. 1997 ). Nevertheless, high doses of TA 4 induce cardiac hypertrophy in rats

Open access

Rachel V Richardson, Emma J Batchen, Adrian J W Thomson, Rowan Darroch, Xinlu Pan, Eva A Rog-Zielinska, Wiktoria Wyrzykowska, Kathleen Scullion, Emad A S Al-Dujaili, Mary E Diaz, Carmel M Moran, Christopher J Kenyon, Gillian A Gray and Karen E Chapman

(VSM) MR knockout is protective against age-related hypertension and cardiac hypertrophy, it has negligible effect on blood pressure and heart size in young mice (<7 months of age) ( McCurley et al . 2012 ). The physiological role of GR in the

Free access

Damian G Romero, Ming Yi Zhou, Licy L Yanes, Maria W Plonczynski, Tanganika R Washington, Celso E Gomez-Sanchez and Elise P Gomez-Sanchez

to adapt to acute ventricular pressure overload and cardiac hypertrophy caused by transverse aortic constriction ( Rogers et al. 1999 ). Cardiac RGS4 is involved in diabetic cardiomyopathy since its overexpression confers resistance to

Free access

Timothy J Cole and Morag J Young

showed that cardiomyocyte MR null also contributed to electromechanical responses to cardiac hypertrophy and damage at least in part due to changes in NHE-1 levels and phosphorylation of Calcium/calmodulin kinase 2 (CamKs) ( Bienvenu et al . 2015

Free access

Sung Wook Park, Shawna D Persaud, Stanislas Ogokeh, Tatyana A Meyers, DeWayne Townsend and Li-Na Wei

mouse model ( Zhang et al . 2002 , 2003 ), suggesting that CRABP1 may prevent cardiac hypertrophy and failure, in part, by dampening the activity of CaMKII. This study reveals that CRABP1 is a new physiological regulator of CaMKII and is critical to

Full access

Kehinde Samuel Olaniyi and Lawrence Aderemi Olatunji

, cardiac hypertrophy and liver disease among others, and its beneficial effects have been linked to its anti-inflammatory and antioxidant properties ( Grau et al. 2011 , Million et al . 2013 , Olaniyi & Olatunji 2019 ). Therefore, the present study