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Julia Schultz, Rica Waterstradt, Tobias Kantowski, Annekatrin Rickmann, Florian Reinhardt, Vladimir Sharoyko, Hindrik Mulder, Markus Tiedge and Simone Baltrusch

2001 Control of mitochondrial morphology by a human mitofusin . Journal of Cell Science 114 867 – 874 . Schmitt H Lenzen S Baltrusch S 2011 Glucokinase mediates coupling of glycolysis to mitochondrial metabolism but not to beta

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Aoife Kiely, Neville H McClenaghan, Peter R Flatt and Philip Newsholme

. The additional glucose consumed appeared to be mainly converted to lactate, thus suggesting a shift to anaerobic glycolysis and a shift away from glucose-dependent stimulation–secretion coupling. Partial similarity thus exists with in vivo studies

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Binbin Guan, Wenyi Li, Fengying Li, Yun Xie, Qicheng Ni, Yanyun Gu, Xiaoying Li, Qidi Wang, Hongli Zhang and Guang Ning

replicating pancreatic beta-cells through glycolysis and calcium channels. Endocrinology 152 2589 – 2598 . ( doi:10.1210/en.2010-1372 ) Terauchi Y Takamoto I Kubota N Matsui J Suzuki R Komeda K Hara A Toyoda Y Miwa I

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Rijin Xiao, Leah J Hennings, Thomas M Badger and Frank A Simmen

-regulated expression of GLUT1 is typical for human colon tumors ( Haber et al. 1998 ) to support their growth via enhanced utilization of glucose in glycolysis ( Munoz-Pinedo et al. 2003 ). The tendency for increased Glut1 expression in colon tissue of the SPI

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Mariana Renovato Martins, Anatalia Kutianski Gonzalez Vieira, Érica Patrícia Garcia de Souza and Anibal Sanchez Moura

almost all body tissues ( Shiojima et al . 2002 ). Glucose uptake, glycogen synthesis, glycolysis, glucose oxidation, and inhibition of fatty acid oxidation are all insulin-dependent processes in various tissues including the cardiac muscle ( Carroll et

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Kasper Faarkrog Høyer, Christoffer Laustsen, Steffen Ringgaard, Haiyun Qi, Christian Østergaard Mariager, Thomas Svava Nielsen, Ulrik Kræmer Sundekilde, Jonas T Treebak, Niels Jessen and Hans Stødkilde-Jørgensen

GLUT2. In the liver, glucose is stored as glycogen or metabolized through glycolysis to form pyruvate ( Samuel & Shulman 2016 ). Pyruvate is a key intermediate in several metabolic pathways and can act as a substrate in hepatic glucose production ( Rui

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Anne H van der Spek, Eric Fliers and Anita Boelen

presentation and can elicit a T-cell response ( Hume 2008 ). M1 polarization is accompanied by changes in cellular metabolism, shifting towards enhanced glycolysis ( Freemerman et al . 2014 , Galvan-Pena & O’Neill 2014 , Zhu et al . 2015 ). Essential

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Brit H Boehmer, Sean W Limesand and Paul J Rozance

, the primary insulin secretagogue, is metabolized through glycolysis and the tricarboxylic acid (TCA) cycle stimulating ATP production, elevating the cytosolic ATP/ADP ratio causing β-cell membrane depolarization, increased cytosolic calcium

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Haijiang Wu, Xinna Deng, Yonghong Shi, Ye Su, Jinying Wei and Huijun Duan

-enriched transcription factor that regulates the metabolism of glucose, fatty acids, amino acids, cholesterol, lipids, bile acids and drugs, whereas its dysfunction leads to impaired glucose transport and glycolysis. It is coactivated by PGC-1α. Several studies have

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Mohammed Bensellam, Jean-Christophe Jonas and D Ross Laybutt

fasted state ( Sekine et al . 1994 , Schuit et al . 1999 ). Glucose-6-phosphate is then oxidized by glycolysis to generate ATP, NADH and pyruvate. Because β-cells present another remarkable feature of expressing very low levels of lactate dehydrogenase