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Apiwan Arinno, Nattayaporn Apaijai, Puntarik Kaewthep, Wasana Pratchayasakul, Thidarat Jaiwongkam, Sasiwan Kerdphoo, Siriporn C Chattipakorn and Nipon Chattipakorn

manuscript, revision of the manuscript and final approval. References Abdelsalam RM Safar MM 2015 Neuroprotective effects of vildagliptin in rat rotenone Parkinson’s disease model: role of RAGE-NFkappaB and Nrf2-antioxidant signaling pathways

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Hyunju Chung, Endan Li, Yumi Kim, Sehee Kim and Seungjoon Park

neurogenesis in the hippocampus in the normal brain because this structure is important in the process of learning, memory, and emotional responses ( Zhao et al . 2008 ). Several endogenous growth factors, such as fibroblast growth factor-2, IGF1, and vascular

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Shannon M Bailey, Uduak S Udoh and Martin E Young

) and NRF2. Genetic control over mitochondrial biogenesis by these factors is coordinated by the peroxisome proliferator-activated receptor-γ coactivator 1 (PGC1) family of transcriptional coactivators. PGC1α and PGC1β dock with the DNA

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E Meimaridou, M Goldsworthy, V Chortis, E Fragouli, P A Foster, W Arlt, R Cox and L A Metherell

Endocrinology and Metabolism 94 936 – 939 . ( https://doi.org/10.1210/jc.2008-1118 ) 10.1210/jc.2008-1118 Saha D Koli S Reddy KVR 2017 Transcriptional regulation of Hb-α and Hb-β through nuclear factor E2-related factor-2 (Nrf2) activation

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Irene Andrés-Blasco, Andrea Herrero-Cervera, Ángela Vinué, Sergio Martínez-Hervás, Laura Piqueras, María Jesús Sanz, Deborah Jane Burks and Herminia González-Navarro

.22578 ) Song Y Li X Li Y Li N Shi X Ding H Zhang Y Li X Liu G Wang Z 2014 Non-esterified fatty acids activate the ROS-p38-p53/Nrf2 signaling pathway to induce bovine hepatocyte apoptosis in vitro . Apoptosis 19 984 – 997

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Pongpan Tanajak, Hiranya Pintana, Natthaphat Siri-Angkul, Juthamas Khamseekaew, Nattayaporn Apaijai, Siriporn C Chattipakorn and Nipon Chattipakorn

G Song L Zhang T 2015 Fibroblast growth factor (FGF21) protects mouse liver against D-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways . Molecular and Cellular Biochemistry 403 287 – 299

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Mary C Sugden, Paul W Caton and Mark J Holness

coactivator 1α; PPARα, peroxisome proliferator-activated receptor α; PPRE, PPAR response element; PRMT1, protein arginine methyltransferase 1; RXR, retinoid X receptor; SIRT1, sirtuin 2 ortholog 1. Regulation of NRs by PGC-1α The PGC-1s are a small family of

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Mohammed Bensellam, Jean-Christophe Jonas and D Ross Laybutt

Feng Y Sokol ES Tillman EJ Sanduja S Reinhardt F Gupta PB 2014 De-differentiation confers multidrug resistance via noncanonical PERK-Nrf2 signaling . PLoS Biology 12 e1001945 . ( https://doi.org/10.1371/journal

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Sheree D Martin and Sean L McGee

2 diabetes, cardiovascular disease and cancer ( Eyre et al . 2004 ). While common molecular mechanisms are only just beginning to emerge, there has been a wealth of epidemiological data describing the overlap between many of the diseases. Among this

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Nigel Turner, Gregory J Cooney, Edward W Kraegen and Clinton R Bruce

into short chain (2–6 carbon atoms), medium chain (8–12 carbon atoms), long chain (14–18 carbon atoms) and very long chain (20–26 carbon atoms). The major types of FAs in the circulation and in the tissues of mammals are the long-chain and very