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Chandrika D Mahalingam, Bharat Reddy Sampathi, Sonali Sharma, Tanuka Datta, Varsha Das, Abdul B Abou-Samra and Nabanita S Datta

and death in astrocytes and possibly contributes to sexual dimorphisms in brain development ( Zhang et al . 2002 ). MAPKs regulate cyclin D1 ( Terada et al . 1999 ), an unique regulator of cell cycle progression and cell proliferation ( Sherr

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Lidia I Serova, Heather A Harris, Shreekrishna Maharjan and Esther L Sabban

) , Matthews & Gustafsson (2003) and Harris (2007) ). ERβ is suggested to be crucially involved in regulating non-reproductive behaviors and brain development. Female ERβ knockout (KO) mice display increased anxiety and reduced cognitive function ( Krezel et

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Milutin Milenkovic, Xavier De Deken, Ling Jin, Mario De Felice, Roberto Di Lauro, Jacques E Dumont, Bernard Corvilain and Francoise Miot

. Lazzaro D , Price M, De Felice M & Di Lauro R 1991 The transcription factor TTF-1 is expressed at the onset of thyroid and lung morphogenesis and in restricted regions of the foetal brain. Development 113 1093 –1104

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Miroslav Adzic, Jelena Djordjevic, Ana Djordjevic, Ana Niciforovic, Constantinos Demonacos, Marija Radojcic and Marija Krstic-Demonacos

A Jekyll and Hyde kinase: roles for Cdk5 in brain development and disease . Current Opinion in Neurobiology 14 390 – 394 . Davies L Karthikeyan N Lynch JT Sial EA Gkourtsa A Demonacos C Krstic-Demonacos M 2008 Cross talk of

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Lucas Monje, Jorgelina Varayoud, Enrique H Luque and Jorge G Ramos

–response curve ( Nishizawa et al. 2005 , Wetherill et al. 2005 , Zsarnovszky et al. 2005 ), where much of the effects observed with low-dose treatments are absent in traditional high-dose toxicological studies. During perinatal brain development

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Ichiro Kaneko, Rimpi K Saini, Kristin P Griffin, G Kerr Whitfield, Mark R Haussler and Peter W Jurutka

activator of endogenous tyrosine hydroxylase in neural progenitor cells derived from the adult brain . Development 126 4017 – 4026 . Shimada T Hasegawa H Yamazaki Y Muto T Hino R Takeuchi Y Fujita T Nakahara K Fukumoto S Yamashita T

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Marian Joëls

manifest in HPA axis disturbances when combined with multiple exposures to major life events, especially when these take place during development of the HPA axis or during brain development. Altered HPA-axis responsiveness has been described in relation to

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Sarah L Alderman and Mathilakath M Vijayan

described neurogenic regions of the zebrafish brain ( Zupanc et al . 2005 , Grandel et al . 2006 ). In fetal mammals, Hsd11b2 prevents untimely neural differentiation by glucocorticoids and is required for normal brain development ( Diaz et al . 1998

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Marion Walser, Maria Teresa Samà, Ruth Wickelgren, Maria Åberg, Mohammad Bohlooly-Y, Bob Olsson, Jan Törnell, Jörgen Isgaard and N David Åberg

status in growth hormone deficient patients: a meta-analysis . Health and Quality of Life Outcomes 3 63 . ( doi:10.1186/1477-7525-3-63 ) D'Ercole AJ Ye P 2008 Expanding the mind: insulin-like growth factor I and brain development

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Ananda Malta, Júlio Cezar de Oliveira, Tatiane Aparecida da Silva Ribeiro, Laize Peron Tófolo, Luiz Felipe Barella, Kelly Valério Prates, Rosiane Aparecida Miranda, Ghada Elmhiri, Claudinéia Conationi da Silva Franco, Aryane Rodrigues Agostinho, Amanda Bianchi Trombini, Audrei Pavanello, Clarice Gravena, Latifa Abdennebi-Najar and Paulo Cezar de Freitas Mathias

Famine exposure in the young and the risk of type 2 diabetes in adulthood . Diabetes 61 2255 – 2260 . ( doi:10.2337/db11-1559 ) Alamy M Bengelloun WA 2012 Malnutrition and brain development: an analysis of the effects of inadequate diet