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Ying-Ying Tsai, William E Rainey and Wendy B Bollag

weights and inflammatory marker levels, mimicking the effects of a glucocorticoid (deoxycorticosterone), in an experimental rodent model of cardiac hypertrophy and fibrosis ( Young et al . 2003 ). These results suggest that endogenous glucocorticoid

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Muraly Puttabyatappa, Robert M Sargis and Vasantha Padmanabhan

are associated with the development of cardiovascular defects ( Gaillard 2015 ). In sheep models of maternal obesity, offspring manifest hyperinsulinemia with increased activation of AKT, ERK, and mTOR in cardiac tissues with cardiac hypertrophy

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Márta Szaszák, Hung-Dar Chen, Hao-Chia Chen, Albert Baukal, László Hunyady and Kevin J Catt

pathogenesis of renal diseases and several cardiovascular disorders, including hypertension, cardiac hypertrophy, and atherosclerosis, and has been implicated in the Marfan syndrome and cancer. In addition to its classical target tissues, local AngII formation

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Marina C Muñoz, Valeria Burghi, Johanna G Miquet, Jorge F Giani, Ricardo D Banegas, Jorge E Toblli, Yimin Fang, Feiya Wang, Andrzej Bartke and Fernando P Dominici

the ACE2/Ang-(1–7)/Mas axis is involved in GH-mediated hypertension. Given the well-demonstrated beneficial effect of Ang-(1–7) in terms of reversal of cardiac hypertrophy ( Grobe et al . 2007 , Giani et al . 2010 ) and renal damage ( Benter et al

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Aline Cordeiro, Luana Lopes Souza, Marcelo Einicker-Lamas and Carmen Cabanelas Pazos-Moura

adipose tissue of rats treated with triiodothyronine . European Journal of Biochemistry 26 553 – 559 . ( doi:10.1111/j.1432-1033.1972.tb01798.x ) Dillmann W 2010 Cardiac hypertrophy and thyroid hormone signaling . Heart Failure Reviews 15

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Alison J Forhead, Juanita K Jellyman, Katherine Gillham, Janelle W Ward, Dominique Blache and Abigail L Fowden

cytoarchitecture and secretory activity . Quarterly Journal of Experimental Physiology 68 15 – 27 . Segar JL Scholz TD Bedell KA Smith OM Huss DJ Guillery EN 1997 Angiotensin AT 1 receptor blockade fails to attenuate pressure-overload cardiac

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Michele O Wilson, Bryony A McNeill, Graham K Barrell, Timothy C R Prickett and Eric A Espiner

.11.008 ) 19948188 10.1016/j.brainresrev.2009.11.008 Pemberton CJ Yandle TG Charles CJ Rademaker MT Aitken GD Espiner EA 1997 Ovine brain natriuretic peptide in cardiac tissues and plasma: effects of cardiac hypertrophy and heart failure

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Hao Wu, Junduo Wu, Shengzhu Zhou, Wenlin Huang, Ying Li, Huan Zhang, Junnan Wang and Ye Jia

induced cardiac hypertrophy . Molecular and Cellular Biochemistry 417 191 – 203 . ( 27221738 10.1007/s11010-016-2729-7 Rodgers JT Lerin C Haas W Gygi SP Spiegelman BM Puigserver P 2005 Nutrient control

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Ji-Eun Kim, Seung Eun Song, Yong-Woon Kim, Jong-Yeon Kim, Sung-Chul Park, Yoon-Ki Park, Suk-Hwan Baek, In Kyu Lee and So-Young Park

.vetimm.2003.09.005 . Takimoto E Kass DA 2007 Role of oxidative stress in cardiac hypertrophy and remodeling . Hypertension 49 241 – 248 doi:10.1161/01.HYP.0000254415.31362.a7 . Tan KC Xu A Chow WS Lam MC Ai VH Tam SC Lam KS 2004

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Peter J Fuller, Yizou Yao, Jun Yang and Morag J Young

.mce.2003.10.009 . Qin W Rudolph AE Bond BR Rocha R Blomme EAG Goeliner JJ Funder JW McMahon EG 2003 Transgenic model of aldosterone-driven cardiac hypertrophy and heart failure . Circulation Research 93 69 – 76 . doi:10.1161/01.RES