development of metabolic disease ( Trujillo & Scherer 2006 ). Figure 1 Adipocytokines and metabolic inflammation in adipose tissue. Adipocytokines derived from adipose tissue are the results of intertwined interaction between adipocytes and immune cells that
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Sy-Ying Leu, Yi-Ling Tsang, Li-Chun Ho, Ching-Chun Yang, Ai-Ning Shao, Chia-Yu Chang, Hui-Kuan Lin, Pei-Jane Tsai, Junne-Ming Sung, and Yau-Sheng Tsai
Introduction The prevalence of metabolic diseases has increased significantly in recent years. The World Health Organization has identified obesity as a significant public health problem ( Chooi et al. 2019 ). Moreover, type 2 diabetes
Rachel Botchlett, Shih-Lung Woo, Mengyang Liu, Ya Pei, Xin Guo, Honggui Li, and Chaodong Wu
Introduction With the increasing prevalence of obesity worldwide, there is a drastic rise in the incidence of metabolic diseases. Metabolic syndrome, type 2 diabetes mellitus (T2DM)/insulin resistance, and cardiovascular disease are only a few
H Y Li, Y X Liu, L Harvey, S Shafaeizadeh, E M van der Beek, and W Han
, minimizing environmental stressors to fetus/offspring. Our data suggest that such temporal and mild maternal GDM exposure increases vulnerability for metabolic disease in the offspring. Our protocol allows scalable generation of a large cohort of GDM dams and
Kook Hwan Kim and Myung-Shik Lee
that are currently available or are being developed for the treatment of metabolic diseases have a potential to induce FGF21. Here, we will review the functional role and molecular mechanisms of FGF21 induction by anti-diabetic drugs. Metformin and FGF
Prashant Regmi, Rajesh Chaudhary, Amanda J Page, Amy T Hutchison, Andrew D Vincent, Bo Liu, and Leonie Heilbronn
.1016/j.celrep.2019.03.064 ) Hatori M Vollmers C Zarrinpar A DiTacchio L Bushong EA Gill S Leblanc M Chaix A Joens M Fitzpatrick JA et al . 2012 Time-restricted feeding without reducing caloric intake prevents metabolic diseases in
Marion Régnier, Matthias Van Hul, Claude Knauf, and Patrice D Cani
outcomes. We discuss the role of different metabolites produced by the microbiota in host metabolism and how specific nutrients may promote either beneficial or deleterious effects on host health. Role of microbiota in the onset of metabolic diseases
Marion Régnier, Matthias Van Hul, Claude Knauf, and Patrice D Cani
L E Nicol, W F Grant, S M Comstock, M L Nguyen, M S Smith, K L Grove, and D L Marks
has left practitioners with a multitude of questions of when to medically intervene in the hope of preventing future cardiovascular complications. Whether an overweight or obese child goes on to develop clear clinical metabolic disease as detected by
Wonsuk Choi, Joon Ho Moon, and Hail Kim
which dysfunctional peripheral 5-HT signaling can progress to metabolic diseases, and how peripheral 5-HT signaling could be a therapeutic target in patients with metabolic diseases. Metabolic roles of 5-HT in pancreatic β-cells Maintenance of
