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Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, Sydney, Australia
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mice, Pierce et al. (2022) , showed that low bone mass and the accumulation of bone marrow adipose tissue persisted with ageing in 21-month-old GR Osx1 mice compared to controls. In particular, GR Osx1 mice displayed impaired cortical bone growth
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decrease in serum testosterone concentration in middle to older aged men is associated with a reduction serum SHBG with mid-normal serum LH and FSH and is characterised by an accumulation of visceral adipose tissue associated with insulin resistance