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Introduction Diabetes-related foot disease (DFD) is defined as ulceration, infection or destruction of tissues of the foot in a person with current or previously diagnosed diabetes mellitus, usually associated with the risk factors of
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reversible with weight loss ( Grossmann 2018 ) and does not demonstrate androgen deficiency. Although weight loss will both increase serum testosterone and prevent type 2 diabetes (T2D), it is unclear whether this effect is mediated directly by the increase
Department of Endocrinology and Diabetes, Monash Health, Victoria, Australia
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Department of Endocrinology and Diabetes, Monash Health, Victoria, Australia
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Department of Endocrinology and Diabetes, Monash Health, Victoria, Australia
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manifestations arise in childhood and health impacts evolve across adolescent years and adult life ( Teede et al. 2010 ). PCOS has significant metabolic (obesity, metabolic syndrome, impaired glucose tolerance, type 2 diabetes, cardiovascular risk factors
Department of Medicine, Monash University, Clayton, Victoria, Australia
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, tubulointerstitial inflammation and scarring in renal biopsies from patients with PA ( Grady et al. 1996 , Blasi et al. 2003 ). Hyperaldosteronism may also have an impact on metabolic parameters. A systematic review found an increased risk of diabetes (OR 1
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with GHD and because GH increases insulin resistance, there has been concern about the risk of developing metabolic syndrome or diabetes during GH therapy. A meta-analysis of 13 studies reported an average increase of 0.22 mmol/L in fasting glucose
South Australian Adult Genetics Unit, Royal Adelaide Hospital, Adelaide, Australia
Adelaide Medical School, University of Adelaide, Adelaide, Australia
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Garvan Institute of Medical Research, Sydney, NSW, Australia
St Vincent’s Clinical School, University of New South Wales, Sydney, NSW, Australia
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St Vincent’s Clinical School, University of New South Wales, Sydney, NSW, Australia
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Academy for Medical Education, Faculty of Medicine, the University of Queensland, Brisbane, Australia
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Garvan Institute of Medical Research, Sydney, NSW, Australia
St Vincent’s Clinical School, University of New South Wales, Sydney, NSW, Australia
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an isolated pituitary macroprolactinoma . Endocrinology, Diabetes and Metabolism Case Reports 2018 18-0078 . ( https://doi.org/10.1530/EDM-18-0078 ) Manojlovic-Gacic E Skender-Gazibara M Popovic V Soldatovic I Boricic N Raicevic S Pekic
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Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, Sydney, Australia
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, hypertension, and metabolic disturbances such as insulin resistance, diabetes, and weight gain ( Buttgereit et al. 2005 , Fardet & Fève 2014 ). Intriguingly, it has been shown that deletion of the GR or exogenous glucocorticoid treatment in mice can both
Mothers and Babies Research Program, Hunter Medical Research Institute, New Lambton Heights, New South Wales, Australia
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that having at least one comorbidity, including hypertension, heart disease, obesity, type 2 diabetes mellitus, chronic lung disease, or cancer, resulted in significantly worse outcomes in COVID-19 hospitalised patients ( Mason et al. 2021 ). In fact
