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Fabio Arturo Iannotti
Fabio Arturo Iannotti
Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, Pozzuoli, Campania, Italy
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Vincenzo Di Marzo
Vincenzo Di Marzo
Director, Joint International Research Unit for the Chemical and Biomolecular Study of the Microbiome in Metabolic Health and Nutrition (JIRU-MicroMeNu) between the Consiglio Nazionale delle Ricerche (CNR, Institute of Biomolecular Chemistry) and Université Laval, Naples, Campania, Italy
Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Department of Medicine, Faculty of Medicine and School of Nutrition, Faculty of Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Québec City, Canada
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Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Department of Medicine, Faculty of Medicine and School of Nutrition, Faculty of Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Québec City, Canada
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endocannabinoidome (eCBome), their role in metabolic control, dysmetabolism and its consequences, and their cross-talk. Grey arrows denote the best-established mechanisms through which the adipose tissue and the gut eCBomes affect the brain (mostly the hypothalamus
Erica Yeo
Erica Yeo
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
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Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
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Patricia L Brubaker
Patricia L Brubaker
Department of Physiology, University of Toronto, Toronto, ON, Canada
Department of Medicine, University of Toronto, Toronto, ON, Canada
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Department of Medicine, University of Toronto, Toronto, ON, Canada
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Deborah M Sloboda
Deborah M Sloboda
Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada
Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Department of Obstetrics, Gynecology and Pediatrics, McMaster University, Hamilton, ON, Canada
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Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada
Department of Obstetrics, Gynecology and Pediatrics, McMaster University, Hamilton, ON, Canada
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well as neurons in the caudal brainstem and hypothalamus ( Müller et al. 2019 ). Transcription factors PAX6, CDX2 and CREB regulate the expression of Gcg in L- and α-cells ( Jin 2008 ). Wnt signaling molecules, GSK-3B and TCF4, are also involved in
