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Targeting activins and inhibins to treat reproductive disorders and cancer cachexia

Adam Hagg

Adam Hagg School of Biomedical Sciences, University of Queensland, Brisbane, Australia

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Eliza O’Shea

Eliza O’Shea School of Biomedical Sciences, University of Queensland, Brisbane, Australia

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Craig A Harrison

Craig A Harrison Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia

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, and

Kelly L Walton

Kelly L Walton School of Biomedical Sciences, University of Queensland, Brisbane, Australia
Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Australia

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growing ovarian follicles, whereas inhibin A is a product of dominant follicles and, following ovulation, the corpus luteum ( Groome et al. 1996 ). Consequently, inhibin A and inhibin B serum levels fluctuate across the menstrual cycle, with inhibin B