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Xiaojiong Du, Sirong He, Yaowen Jiang, Lingling Wei and Weiming Hu

become the key link that could prolong graft function and survival and improve the success rate of clinical islet transplantation. Adiponectin is the most abundant adipose-specific adipokine that acts as an anti-obesity and anti-inflammatory hormone

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Ellen R Lubbers, Edward O List, Adam Jara, Lucila Sackman-Sala, Jose Cordoba-Chacon, Manuel D Gahete, Rhonda D Kineman, Ravneet Boparai, Andrzej Bartke, John J Kopchick and Darlene E Berryman

adiponectin ( Maeda et al . 1996 ). In humans, adiponectin has been shown to decrease in concentration as fat mass increases, unlike most other adipokines ( Arita et al . 1999 , Kern et al . 2003 ). Thus, adiponectin is considered a beneficial adipokine

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Sujith Rajan, Ganesh Panzade, Ankita Srivastava, Kripa Shankar, Rajesh Pandey, Durgesh Kumar, Sanchita Gupta, Abhishek Gupta, Salil Varshney, Muheeb Beg, Raj Kumar Mishra, Ravi Shankar and Anil Gaikwad

important to understand the pathophysiology of IR and type 2 diabetes. Recently, several miRNAs such as miR-378 and miR-193b have been shown to regulate the expression of adiponectin (Belarbi et al . 2015, Chen et al . 2015 , Gao et al . 2015 , Li et

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Eun Hee Koh, Ah-Ram Kim, Hyunshik Kim, Jin Hee Kim, Hye-Sun Park, Myoung Seok Ko, Mi-Ok Kim, Hyuk-Joong Kim, Bum Joong Kim, Hyun Ju Yoo, Su Jung Kim, Jin Sun Oh, Chang-Yun Woo, Jung Eun Jang, Jaechan Leem, Myung Hwan Cho and Ki-Up Lee

Introduction Adiponectin, the most abundant protein in adipocytes, has many favorable effects on metabolism, including improvement of insulin action and reduction of atherosclerotic processes ( Ouchi et al . 2001 , Yamauchi et al . 2003

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Gabriela Capllonch-Amer, Miquel Sbert-Roig, Bel M Galmés-Pascual, Ana M Proenza, Isabel Lladó, Magdalena Gianotti and Francisco J García-Palmer

adiponectin levels in serum. Adiponectin is an insulin-sensitizing hormone secreted mainly by white adipose tissue (WAT; Harwood 2012 ). Circulating levels of adiponectin show sexual dimorphism in both humans and rodents, with females presenting higher serum

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Thanh Q Dang, Nanyoung Yoon, Helen Chasiotis, Emily C Dunford, Qilong Feng, Pingnian He, Michael C Riddell, Scott P Kelly and Gary Sweeney

with 50 µg/mL Neomycin (Sigma-Aldrich) for 24 h, cells were seeded onto inserts for analysis of TEER, examining adiponectin flux or preparation of cell lysates to confirm claudin-7 knockdown. Transendothelial electrical resistance (TEER), and [3H

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Delphine Benaitreau, Esther Dos Santos, Marie-Christine Leneveu, Nadia Alfaidy, Jean-Jacques Feige, Philippe de Mazancourt, René Pecquery and Marie-Noëlle Dieudonné

signaling mediated by growth factors, cytokines, and hormones of both fetal and maternal origin ( Bischof et al . 2000 , Cohen & Bischof 2007 , Knofler et al . 2008 ). Adiponectin, a hormone mainly produced in adipose tissue, has been described as an

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Peter J Simons, Petra S van den Pangaart, Johannes M F G Aerts and Louis Boon

Introduction Adiponectin is a hormone that is produced predominantly by adipocytes ( Scherer et al. 1995 ), and has been shown to have anti-diabetic, anti-atherogenic, and anti-inflammatory properties ( Trujillo & Scherer 2005

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Katsumori Segawa, Morihiro Matsuda, Atsunori Fukuhara, Kentaro Morita, Yosuke Okuno, Ryutaro Komuro and Iichiro Shimomura

Introduction There is sufficient evidence that adipose tissue is not only an energy storage organ, but it produces and secretes a variety of bioactive molecules called adipocytokines, such as tumor necrosis factor α, leptin, adiponectin, plasminogen

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Chang-Jiang Li, Hui-Wen Sun, Fa-Liang Zhu, Liang Chen, Yuan-Yuan Rong, Yun Zhang and Mei Zhang

Introduction Secreted by adipocytes, adiponectin is a collagen-like protein with significant roles in regulating the metabolism of glucose and fatty acids. Low plasma adiponectin levels are associated with insulin resistance and risk