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Liping Luo and Meilian Liu

Introduction Adipose tissue, which is primarily composed of adipocytes as well as pre-adipocytes, macrophages, endothelial cells, fibroblasts, and leucocytes, has been increasingly recognized as a major player of systemically metabolic

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Carsten T Herz and Florian W Kiefer

Adipose tissue browning and whitening A hallmark feature of adipose tissue browning is the induction of thermogenically active adipocytes in white fat depots. These adipocytes are often referred to as beige or brite (brown in white) cells and

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Felipe de Oliveira Franco, Magno Alves Lopes, Felipe dos Santos Henriques, Rodrigo Xavier das Neves, Cesário Bianchi Filho and Miguel Luiz Batista Jr

loss is the main marker of cachectic syndrome, followed by atrophy of both skeletal muscle and adipose tissue (AT) ( Das et al . 2011 , Batista et al . 2012 , Seelaender & Batista 2014 ). In this regard, several studies have postulated that AT

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Eun-Kyung Choi, Woon-Ki Kim, Ok-Joo Sul, Yun-Kyung Park, Eun-Sook Kim, Jae-Hee Suh, Rina Yu and Hye-Seon Choi

observed in OVX. Increased fat leads to the accumulation of adipose tissue macrophage (ATM), which plays a critical role in chronic inflammation and development of insulin resistance (IR) ( Shoelson et al . 2007 ). Exacerbation of insulin sensitivity is

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James C Needell, Madalyn N Brown and Danny Zipris

et al . 2010 , Hara et al . 2012 , 2013 , 2014 , Needell et al . 2017 ). In the course of our studies, we observed that infection of LEW1.WR1 rats with KRV induces cell influx into adipose tissue detected on day 5 post infection prior to β cell

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Monisha Rajasekaran, Ok-Joo Sul, Eun-Kyung Choi, Ji-Eun Kim, Jae-Hee Suh and Hye-Seon Choi

a potential therapeutic target for inflammatory diseases such as rheumatoid arthritis, multiple sclerosis and obesity-associated metabolic syndrome. Brown adipose tissue (BAT) catabolizes lipids to generate heat by expressing uncoupling protein 1

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Karen Oliva, Gillian Barker, Gregory E Rice, Mark J Bailey and Martha Lappas

pathophysiology of GDM is essential in order to provide the best opportunity for early treatment to prevent onset or progression of the disease. During human pregnancy, a number of metabolic changes occur in maternal adipose tissue that are essential for fetal

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Patrik Šimják, Anna Cinkajzlová, Kateřina Anderlová, Antonín Pařízek, Miloš Mráz, Michal Kršek and Martin Haluzík

glucose metabolism. Increasing evidence from clinical and experimental studies indicates that metabolic and endocrine dysfunction of adipose tissue plays an important role in the pathophysiology of GDM. Figure 1 GDM: risk factors and consequences

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Martha Lappas

a number of changes in maternal adipose tissue, which may play an important role in the growth and development of the foetus. For example, maternal adipose tissue's insulin resistance, an important adaptation that occurs in the later part of

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Jay W Porter, Joe L Rowles III, Justin A Fletcher, Terese M Zidon, Nathan C Winn, Leighton T McCabe, Young-Min Park, James W Perfield II, John P Thyfault, R Scott Rector, Jaume Padilla and Victoria J Vieira-Potter

Introduction Two major types of adipose tissue (AT) exist: white (WAT), primarily serving as the body’s major energy storage site and brown (BAT), which predominately converts energy into heat through uncoupled respiration. AT is an active