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Ken Takao, Katsumi Iizuka, Yanyan Liu, Teruaki Sakurai, Sodai Kubota, Saki Kubota-Okamoto, Toshinori Imaizumi, Yoshihiro Takahashi, Yermek Rakhat, Satoko Komori, Tokuyuki Hirose, Kenta Nonomura, Takehiro Kato, Masami Mizuno, Tetsuya Suwa, Yukio Horikawa, Masakatsu Sone, and Daisuke Yabe

2016 ). Steroid hormone synthesis in mouse adrenal glands requires the action of scavenger receptor class B type 1 ( Scrab1 ), which takes up cholesteryl esters from high-density lipoprotein (HDL) in circulation ( Kraemer 2007 ). Cholesteryl esters are

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T V Novoselova, D Jackson, D C Campbell, A J L Clark, and L F Chan

Hypothalamic–pituitary–adrenal axis The adrenal glands are responsible for releasing different classes of hormones. The inner part of the glands, the medulla, secretes catecholamines under the control of the sympathetic nervous system. The outer

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Dario R Lemos, Jodi L Downs, Martin N Raitiere, and Henryk F Urbanski

present study, we used the rhesus macaque animal model to examine if circannual changes in day length can significantly influence adrenal gland function. Specifically, our first aim was to examine the effect of different photoperiods on plasma

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Damian G Romero, Ming Yi Zhou, Licy L Yanes, Maria W Plonczynski, Tanganika R Washington, Celso E Gomez-Sanchez, and Elise P Gomez-Sanchez

. 2006 , Sato et al. 2006 ). G-protein signaling pathways are essential for adrenal gland regulation. Peptide hormones angiotensin II (Ang II), adrenocorticotrophic hormone (ACTH), and endothelin-1, potent physiological inducers of adrenal

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Chen-Che Jeff Huang and Yuan Kang

Introduction Zona glomerulosa (ZG), zona fasciculata (ZF) and zona reticularis (ZR) are the three major cortical zones (definitive zones) in the mammalian adrenal gland. In human fetal adrenals, there is another cortical layer in the inner

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Marie-Claude Battista, Claude Roberge, Mélissa Otis, and Nicole Gallo-Payet

order of picomolar, compared with the micromolar range for cortisol/corticosterone ( Gallo-Payet & Payet 1989 , Rainey 1999 , Sewer & Waterman 2003 ). The adrenal gland undergoes constant dynamic structural changes and is generally well acknowledged

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Adina Dumitrescu, Graham W Aberdeen, Gerald J Pepe, and Eugene D Albrecht

Introduction The human and nonhuman primate fetal adrenal glands undergo a highly unique pattern of cortical zone-specific intrauterine growth and development. Throughout pregnancy, the fetal adrenal cortex is comprised primarily of

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Mélissa Otis, Shirley Campbell, Marcel D Payet, and Nicole Gallo-Payet

). From these observations, we raised the hypothesis that the nature of extracellular matrix (ECM) and integrins could influence cell responses to ACTH, as also observed in the human foetal adrenal gland ( Chamoux et al. 2002 ). Several studies

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Karine Bibeau, Mélissa Otis, Jean St-Louis, Nicole Gallo-Payet, and Michèle Brochu

aldosterone synthase (P450aldo; Bassett et al . 2004 , Capponi 2004 ). In contrast to several adult tissues, AT 2 R is relatively highly expressed in the adult adrenal glands (ZG and medulla; Breault et al . 1996 , Frei et al . 2001 , Macova

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Salvatore Valiante, Marina Prisco, Rosaria Sciarrillo, Maria De Falco, Anna Capaldo, Flaminia Gay, Piero Andreuccetti, Vincenza Laforgia, and Lorenzo Varano

neuropeptides can directly stimulate adrenal glands. It has been demonstrated that PACAP is able to enhance the expression of tyrosine hydroxylase, dopamine β-hydroxylase and phenylethanolamine N -methyltransferase, the enzymes involved in the synthesis of