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Iyad H Manaserh, Emily Maly, Marziyeh Jahromi, Lakshmikanth Chikkamenahalli, Joshua Park, and Jennifer Hill

component of body weight regulation. Provided they have a sufficient caloric supply, mammals are able to maintain their body temperature in a cold environment by vasoconstriction to avoid heat loss from the extremities and by shivering to generate heat from

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Md Nurul Islam, Yuichiro Mita, Keisuke Maruyama, Ryota Tanida, Weidong Zhang, Hideyuki Sakoda, and Masamitsu Nakazato

, and body temperature. We also monitored plasma LEAP2 level and liver Leap2 expression under ad libitum, fasting, and re-feeding conditions. Finally, we sought to identify the mechanism of Leap2 expression in the liver. Materials and methods

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Alison Mostyn, Linda Attig, Thibaut Larcher, Samir Dou, Pascale Chavatte-Palmer, Monia Boukthir, Arieh Gertler, Jean Djiane, Michael E Symonds, and Latifa Abdennebi-Najar

analyses, the level of significance was set at P <0.05. All values are expressed as means± s.e.m. (except for body temperatures where the values are expressed as mean± s.e. ). Results Piglet mortality, postnatal growth, thermoregulation and metabolic

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Victoria Diedrich, Elena Haugg, Carola Dreier, and Annika Herwig

resources are limited and at the same time ambient temperature is low; a combination that hampers maintenance of a high body temperature. In response to this energetic challenge, mammals are able to regularly shut down their metabolism to fractions of

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Matthew J VandeKopple, Jinghai Wu, Lisa A Baer, Naresh C Bal, Santosh K Maurya, Anuradha Kalyanasundaram, Muthu Periasamy, Kristin I Stanford, Amato J Giaccia, Nicholas C Denko, and Ioanna Papandreou

, hepatitis C virus replication, liver steatosis and cancer cell survival ( Reue 2011 , Bensaad et al. 2014 , Qiu et al. 2015 ). Eutherian mammals have evolved multiple mechanisms to maintain a stable core body temperature. Broadly, these mechanisms

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1. Thyroid activity was studied with 131I injected intraperitoneally. The uptake of 131I was followed in the living animal. The animals were brought into a state of hypoxic hypothermia by Giaja's method [1940].

2. The thyroid gland is completely inactive at body temperatures of between 15 and 20° C.

3. At body temperatures of between 23 and 28° C, thyroid activity is decreased, but is large enough, over a sufficiently long period of time, to concentrate normal quantities of iodine.

4. Thyroid activity is unchanged when a normal body temperature is regained after a single or four to six successive phases of hypothermia.

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Monisha Rajasekaran, Ok-Joo Sul, Eun-Kyung Choi, Ji-Eun Kim, Jae-Hee Suh, and Hye-Seon Choi

for automatic control of data collection and analysis. Body temperature was recorded at 10 m intervals. Female Ccl2 +/+ (wild type (WT)) and Ccl2 KO mice that were 21–22 weeks old were killed by CO 2 asphyxiation and cervical dislocation. Blood

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Jonathan D Johnston and Debra J Skene

(reviewed in Skene & Arendt (2006) ). Compared with core body temperature and cortisol rhythms, melatonin is least affected by activity, sleep, meals and stress. The timing of the rhythm can be measured by estimating the time of melatonin onset, peak or

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S Pearce, H Budge, A Mostyn, E Genever, R Webb, P Ingleton, A M Walker, M E Symonds, and T Stephenson

in body temperature ( Clarke et al. 1996 ). With prolonged exposure to either pituitary extract PRL or S179D PRL, an increase in lipolysis occurred in conjunction with a rise in the thermogenic potential of UCP1. These adaptations occurred over the

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Leena Rastogi, Sushil Gupta, and Madan M Godbole

euthyroid rats (E+S, n =6) and in rats treated with different doses of l -T 4 (T+IR, n =6, for each dose). The core body temperature was monitored manually using a thermoprobe temporarily inserted 2 cm into the rectum in each group of rats. Serum total