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Christina Antza
Christina Antza
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Georgios Kostopoulos
Georgios Kostopoulos
Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece
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Samiul Mostafa
Samiul Mostafa
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
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Krishnarajah Nirantharakumar
Krishnarajah Nirantharakumar
Institute of Applied Health Research, University of Birmingham, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Abd Tahrani
Abd Tahrani
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK
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) ( https://apps.who.int/gho/data/view.main.REGION2480A?lang=en Accessed (September) (2021)). Considering the health and economic consequences associated with obesity (type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD), cancer, mortality), there
Haiyong Chen
Haiyong Chen
Li Ka Sing Faculty of Medicine, Department of Medicine and Therapeutics, Centre for Biosystems and Genome Network Medicine, Department of Clinical Oncology, School of Chinese Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong
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Hui-Yao Lan
Hui-Yao Lan
Li Ka Sing Faculty of Medicine, Department of Medicine and Therapeutics, Centre for Biosystems and Genome Network Medicine, Department of Clinical Oncology, School of Chinese Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong
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Dimitrios H Roukos
Dimitrios H Roukos
Li Ka Sing Faculty of Medicine, Department of Medicine and Therapeutics, Centre for Biosystems and Genome Network Medicine, Department of Clinical Oncology, School of Chinese Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong
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William C Cho
William C Cho
Li Ka Sing Faculty of Medicine, Department of Medicine and Therapeutics, Centre for Biosystems and Genome Network Medicine, Department of Clinical Oncology, School of Chinese Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong
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Introduction Diabetes mellitus (DM) affects 347 million people worldwide. The World Health Organization predicts that diabetes-related deaths could double between 2005 and 2030. The research conducted by American Diabetes Association estimated that
Haijiang Wu
Haijiang Wu
Department of Pathology, Hebei Medical University, Shijiazhuang, China
Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China
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Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China
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Xinna Deng
Xinna Deng
Departments of Oncology & Immunotherapy, Hebei General Hospital, Shijiazhuang, China
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Yonghong Shi
Yonghong Shi
Department of Pathology, Hebei Medical University, Shijiazhuang, China
Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China
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Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China
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Ye Su
Ye Su
Mathew Mailing Centre for Translational Transplantation Studies, Lawson Health Research Institute, London Health Sciences Centre, London, Ontario, Canada
Departments of Medicine and Pathology, University of Western Ontario, London, Ontario, Canada
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Departments of Medicine and Pathology, University of Western Ontario, London, Ontario, Canada
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Jinying Wei
Jinying Wei
Department of Pathology, Hebei Medical University, Shijiazhuang, China
Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China
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Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China
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Huijun Duan
Huijun Duan
Department of Pathology, Hebei Medical University, Shijiazhuang, China
Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China
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Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China
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Introduction Type 2 diabetes mellitus (T2DM) is a chronic metabolic isorder characterized by hyperglycemia in the context of insulin resistance (IR) and insulin secretion deficiency due to β-cell dysfunction. The global prevalence of T2DM is
Sofie Dinesen
Sofie Dinesen
Department of Science and Environment, Roskilde University, Universitetsvej 1, Roskilde, Denmark
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Alisar El-Faitarouni
Alisar El-Faitarouni
Department of Science and Environment, Roskilde University, Universitetsvej 1, Roskilde, Denmark
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Louise T Dalgaard
Louise T Dalgaard
Department of Science and Environment, Roskilde University, Universitetsvej 1, Roskilde, Denmark
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Introduction The current worldwide obesity epidemic drives an increased incidence and prevalence of gestational diabetes mellitus (GDM) as well as type 2 diabetes (T2D) in pregnancy ( Sun et al. 2022 ). In 2019, according to the
Patrik Šimják
Patrik Šimják
Department of Gynaecology and Obstetrics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
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Anna Cinkajzlová
Anna Cinkajzlová
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Kateřina Anderlová
Kateřina Anderlová
Department of Gynaecology and Obstetrics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
3rd Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
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3rd Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
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Antonín Pařízek
Antonín Pařízek
Department of Gynaecology and Obstetrics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
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Miloš Mráz
Miloš Mráz
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Michal Kršek
Michal Kršek
3rd Department of Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
2nd Internal Department, 3rd Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czech Republic
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2nd Internal Department, 3rd Faculty of Medicine, Charles University and University Hospital Královské Vinohrady, Prague, Czech Republic
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Martin Haluzík
Martin Haluzík
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic
Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Introduction Gestational diabetes mellitus (GDM) is the most common metabolic disorder of pregnancy. It is defined as diabetes diagnosed in the second or third trimester of pregnancy in patients with no history of diabetes prior to gestation
Cid Pitombo
Cid Pitombo
Departments of Internal Medicine,
Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Eliana P Araújo
Eliana P Araújo
Departments of Internal Medicine,
Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Cláudio T De Souza
Cláudio T De Souza
Departments of Internal Medicine,
Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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José C Pareja
José C Pareja
Departments of Internal Medicine,
Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Bruno Geloneze
Bruno Geloneze
Departments of Internal Medicine,
Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Lício A Velloso
Lício A Velloso
Departments of Internal Medicine,
Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Surgery, State University of Campinas, UNICAMP, 13083-970, Campinas, Brazil
Department of Surgery, Rio de Janeiro Federal University, Rio de Janeiro, Brazil
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Introduction Visceral adiposity is one of the main risk factors for the development of insulin resistance, diabetes mellitus, hypertension, and cardiovascular disease ( Ferrannini et al. 1997 , Fujimoto et al. 1999 ). The
Anna Cinkajzlová
Anna Cinkajzlová
Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
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Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
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Miloš Mráz
Miloš Mráz
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Martin Haluzík
Martin Haluzík
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine and General University Hospital, Charles University, Prague, Czech Republic
Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Diabetes Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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2010 ). Excessive accumulation of VAT phenotypically presented as android obesity is associated with higher metabolic risk and the development of insulin resistance, arterial hypertension, type 2 diabetes mellitus (T2DM) and cardiovascular diseases
Petra Kaválková
Petra Kaválková
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Miloš Mráz
Miloš Mráz
Third Department of Medicine – Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Pavel Trachta
Pavel Trachta
Third Department of Medicine – Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Jana Kloučková
Jana Kloučková
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Anna Cinkajzlová
Anna Cinkajzlová
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Zdeňka Lacinová
Zdeňka Lacinová
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
Third Department of Medicine – Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Third Department of Medicine – Department of Endocrinology and Metabolism, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Denisa Haluzíková
Denisa Haluzíková
Department of Sports Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Marek Beneš
Marek Beneš
Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Zuzana Vlasáková
Zuzana Vlasáková
Department of Diabetes, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Václav Burda
Václav Burda
Department of Cybernetics, Faculty of Electrical Engineering, Czech Technical University, Prague, Czech Republic
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Daniel Novák
Daniel Novák
Department of Cybernetics, Faculty of Electrical Engineering, Czech Technical University, Prague, Czech Republic
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Tomáš Petr
Tomáš Petr
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Libor Vítek
Libor Vítek
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
Fourth Department of Internal Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Fourth Department of Internal Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
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Terezie Pelikánová
Terezie Pelikánová
Department of Diabetes, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
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Martin Haluzík
Martin Haluzík
Institute of Medical Biochemistry and Laboratory Diagnostics, First Faculty of Medicine, Charles University in Prague and General University Hospital, Prague, Czech Republic
Department of Obesitology, Institute of Endocrinology, Prague, Czech Republic
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Department of Obesitology, Institute of Endocrinology, Prague, Czech Republic
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Introduction The worldwide obesity epidemic together with related pathologies such as type 2 diabetes mellitus (T2DM) and increased risk of cardiovascular mortality and morbidity has underscored the need for effective, reliable and simple
Xuefeng Yang
Xuefeng Yang
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Shuang Mei
Shuang Mei
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Haihua Gu
Haihua Gu
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Huailan Guo
Huailan Guo
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Longying Zha
Longying Zha
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Junwei Cai
Junwei Cai
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Xuefeng Li
Xuefeng Li
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Zhenqi Liu
Zhenqi Liu
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Wenhong Cao
Wenhong Cao
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
Department of Nutrition, Department of Nutrition and Food Hygiene, Department of Preventive Medicine, Department of Nutrition and Food Hygiene, Department of Medicine, Department of Medicine (Endocrinology), Department of Medicine (Endocrinology and Metabolism), Gillings School of Global Public Health, Nutrition Research Institute (NRI) at Kannapolis, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27559, USA
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Introduction Type 2 diabetes mellitus (T2DM) has become a major health and economic burden to industrialized societies. Its negative impact on the general health and economy is still rapidly increasing due to the continuing industrialization. It is
Laura B Lemke
Laura B Lemke
Department of Biological Engineering, Division of Comparative Medicine
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Arlin B Rogers
Arlin B Rogers
Department of Biological Engineering, Division of Comparative Medicine
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Prashant R Nambiar
Prashant R Nambiar
Department of Biological Engineering, Division of Comparative Medicine
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James G Fox
James G Fox
Department of Biological Engineering, Division of Comparative Medicine
Department of Biological Engineering, Division of Comparative Medicine
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Department of Biological Engineering, Division of Comparative Medicine
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pancreatic islets has been described in obese and diabetic subjects (Butler 2003). However, to our knowledge, it has not been previously reported in spontaneous outbred mouse models of diabetes mellitus. Islet neogenesis is thought to occur as a compensatory
