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Hsiu-Chi Lee Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan

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Shaw-Jenq Tsai Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan

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stress and environmental changes, HIF is reported to play an important role in many diseases, such as circulatory disorder, metabolic disorder, inflammatory disease and cancer ( Lin et al . 2014 , Semenza 2014 , Cummins et al . 2016 ). The endocrine

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Derek Ball School of Life Sciences, Heriot-Watt University, Edinburgh EH14 4AS, UK

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muscle metabolic capacity with ageing ( Olesen et al . 2014 ). Recent work has suggested that both skeletal muscle and adipose tissue function as integrated endocrine organs in response to an exercise stimulus ( Pedersen 2013 ). Exercise therefore

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Fiona Roberts Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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Greg Markby Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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Scott Dillon Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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Colin Farquharson Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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Vicky E MacRae Functional Genetics and Development, The Roslin Institute, The University of Edinburgh, Edinburgh, UK

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pathologies and mortality The hormone FGF23 is one of the three endocrine FGF’s, which also includes FGF19 and FGF21 ( Angelin et al. 2012 , Richter & Faul 2018 ). FGF23 is secreted by osteoblasts and osteocytes and plays a critical role in ion mineral

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William Zawatski Pediatric Endocrine Division, Department of Pediatrics

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Mary M Lee
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the past century. Multiple reports, however, also emphasize the potential role of environmental chemicals, specifically endocrine-disrupting compounds (EDCs; Acerini & Hughes 2006 , Euling et al . 2008 b , Mouritsen et al . 2010 , Toppari & Juul

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A P Santos-Silva Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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E Oliveira Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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C R Pinheiro Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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A C Santana Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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C C Nascimento-Saba Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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Y Abreu-Villaça Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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E G Moura Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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P C Lisboa Laboratory of Endocrine Physiology, Laboratory of Morphofunctional Analysis, Laboratory of Neurophysiology

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exposed to tobacco smoke during lactation to better understand the immediate and late repercussions of early environmental smoking on rat offspring's development and endocrine function. Materials and methods Wistar rats were kept in a room with controlled

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Siân E Piret Academic Endocrine Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, University of Oxford, Headington, Oxford OX3 7LJ, UK

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Rajesh V Thakker Academic Endocrine Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, University of Oxford, Headington, Oxford OX3 7LJ, UK

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Introduction In vivo models are required for investigating the physiological mechanisms underlying endocrine and metabolic disorders, and for pre-clinical translational studies and assessments of new treatments. Such in vivo models have

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Abdoulaye Diane Metabolic and Cardiovascular Diseases Laboratory, Department of Sociology, Alberta Institute of Human Nutrition, Alberta Diabetes Institute

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Maria Kupreeva Metabolic and Cardiovascular Diseases Laboratory, Department of Sociology, Alberta Institute of Human Nutrition, Alberta Diabetes Institute

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Faye Borthwick Metabolic and Cardiovascular Diseases Laboratory, Department of Sociology, Alberta Institute of Human Nutrition, Alberta Diabetes Institute

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Spencer D Proctor Metabolic and Cardiovascular Diseases Laboratory, Department of Sociology, Alberta Institute of Human Nutrition, Alberta Diabetes Institute

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W David Pierce Metabolic and Cardiovascular Diseases Laboratory, Department of Sociology, Alberta Institute of Human Nutrition, Alberta Diabetes Institute

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Donna F Vine Metabolic and Cardiovascular Diseases Laboratory, Department of Sociology, Alberta Institute of Human Nutrition, Alberta Diabetes Institute
Metabolic and Cardiovascular Diseases Laboratory, Department of Sociology, Alberta Institute of Human Nutrition, Alberta Diabetes Institute

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Introduction More than 60% of adolescents and women with polycystic ovary syndrome (PCOS) are overweight or obese, and this adiposity is associated with exacerbation of cardiometabolic risk and reproductive-endocrine dysfunction ( Bekx et al . 2010

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Trinna L Cuellar UCSF Diabetes Center, Department of Microbiology and Immunology, University of California, San Francisco, California 94122-0534, USA

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Michael T McManus UCSF Diabetes Center, Department of Microbiology and Immunology, University of California, San Francisco, California 94122-0534, USA

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. 2005 ). miRNAs and endocrine biology Might miRNAs be important for endocrine function and their mis-expression responsible for aberrations in hormone regulation? Last year, the discovery of a pancreatic islet-specific miRNA, miR

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Manuel D Gahete Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Juan M Jiménez-Vacas Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Emilia Alors-Pérez Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Vicente Herrero-Aguayo Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Antonio C Fuentes-Fayos Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Sergio Pedraza-Arévalo Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Justo P Castaño Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Raúl M Luque Maimonides Institute for Biomedical Research of Cordoba (IMIBIC), Córdoba, Spain
Department of Cell Biology, Physiology, and Immunology, Universidad de Córdoba, Córdoba, Spain
Reina Sofia University Hospital, Córdoba, Spain
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Córdoba, Spain
Agrifood Campus of International Excellence (ceiA3), Córdoba, Spain

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Endocrine and neuroendocrine tumors: origin, location, heterogeneity and outcome Cancer and tumor pathologies represent one of the main health problems for the population worldwide, with incidence and death ratios still increasing ( Rusner et

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Geoffrey J Beckett
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John R Arthur
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element is essential for optimal endocrine and immune function and moderating the inflammatory response ( McKenzie et al. 2002 b , Arthur et al. 2003 ). These biological actions are mediated in most cases through the expression of at least 30

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