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Laboratory of Radiobiology and Molecular Genetics, School of Medicine, Department of Internal Medicine and Medical Specialties, Euro-Mediterranean Institute of Science and Technology, Second Propedeutic Department of Internal Medicine, Department of Physiology, Department of Physiology, Institute Vinca, University of Belgrade, PO Box 522, 11000 Belgrade, Serbia
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Laboratory of Radiobiology and Molecular Genetics, School of Medicine, Department of Internal Medicine and Medical Specialties, Euro-Mediterranean Institute of Science and Technology, Second Propedeutic Department of Internal Medicine, Department of Physiology, Department of Physiology, Institute Vinca, University of Belgrade, PO Box 522, 11000 Belgrade, Serbia
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protein concentration contributes to the deficiencies in cardiac contractility in animal models and has been documented in patients with heart failure (HF; Schwinger et al . 2003 , Liu et al . 2012 ). The majority of hormones (e.g. insulin, estradiol
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, Turku Center for Disease Modeling, University of Turku, Turku, Finland
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Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden
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Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
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. 2021 ). Moreover, estradiol is a well-known regulator of bone and immune system homeostasis and also controls motor ability and pain sensitivity ( Straub 2007 ). Although epidemiological studies reported that postmenopausal women have a higher risk to
CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway
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CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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Instituto Maimónides de Investigación Biomédica (IMIBIC)/Hospital Reina Sofía, Córdoba, Spain
FiDiPro Program, University of Turku, Turku, Finland
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CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Santiago de Compostela, Spain
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showed that reduced levels of estradiol (E2) after ovariectomy (OVX) are associated with hyperphagia and decreased energy expenditure, leading to weight gain ( Martínez de Morentin et al. 2014 a , 2015 ). Moreover, variations in the magnitude of
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( Craig et al. 2007 ), and the estradiol synthesized from the granulosa cells is required for the structure and function of female reproductive tissues. Many extra- and intra-ovarian factors have been implicated in granulosa cell proliferation and
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, deCatanzaro et al . 2006 , Khan et al . 2009 , Thorpe & deCatanzaro 2012 ). Indeed, recent data suggest that small lipophilic steroids such as estradiol-17β (E 2 ) could transfer directly between cohabiting individuals ( Guzzo et al . 2010 , 2012 ). The
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is equivalent to that in the ovary, and the estradiol-17β (E 2 ) levels in the portal vein were much higher than those found in arterial blood. Then it was suggested that about 90% of gastric E 2 is bound to estrogen receptors (ER) in the liver. Our
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population at E16.5. The discovery of higher levels of Esr1 in the ARC Kiss1 cells of female fetuses prompted us to compare the direct estradiol responsiveness of ARC Kiss1 cells in vitro specifically sorted from male and female fetuses
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( Bruner et al. 1997 , Pitsos & Kanakas 2009 ). In relation to this, there exists a correlation between the levels of MMP-2 and estradiol in the peritoneal fluid of patients with endometriosis ( Huang et al . 2004 ). In turn, steroid hormones play an
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incubation To study effects of sexual steroids on Fsh and Lh cell proliferation, three groups of tg( lhb -hrGfpII) adult fish (six females and six males) were incubated for 6 days in daily renewed system water containing 100 μg/L of either 17β-estradiol
Instituto de Biología y Medicina Experimental, Department of Medicine, Department of Cell Biology, Consejo Nacional de Investigaciones Científicas y Técnicas, Vuelta de Obligado 2490, 1428 Buenos Aires, Argentina
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SSTR in human prolactinomas ( Jaquet et al. 1999 ). Based on the counteracting effects of estradiol on dopamine action in lactotrophs, targeting of the estrogen receptor with tamoxifen was evaluated in the pre-cabergoline era in patients with