Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 1 - 10 of 751 items for :

  • "glucose metabolism" x
  • Refine by access: All content x
Clear All
Mathis Grossmann Department of Medicine Austin Health, Department of Endocrinology, University of Melbourne, 145 Studley Road, Heidelberg, Victoria 3084, Australia
Department of Medicine Austin Health, Department of Endocrinology, University of Melbourne, 145 Studley Road, Heidelberg, Victoria 3084, Australia

Search for other papers by Mathis Grossmann in
Google Scholar
PubMed Close

70 years of clinical experience. On the other hand, in functional androgen deficiency due to axis suppression because of age-related comorbidities, treatment may aim for a specific health outcome, such as improvement of glucose metabolism, and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-13-0393
Volume/Issue:
Volume 220: Issue 3
Free access
Olivier Dumortier Université Côte d’Azur, Inserm, CNRS, IRCAN, Nice, France

Search for other papers by Olivier Dumortier in
Google Scholar
PubMed Close
,
Gaia Fabris Université Côte d’Azur, Inserm, CNRS, IRCAN, Nice, France
Université Côte d’Azur, CNRS, LP2M, Nice, France

Search for other papers by Gaia Fabris in
Google Scholar
PubMed Close
,
Didier F Pisani Université Côte d’Azur, CNRS, LP2M, Nice, France

Search for other papers by Didier F Pisani in
Google Scholar
PubMed Close
,
Virginie Casamento Université Côte d’Azur, Inserm, CNRS, IRCAN, Nice, France

Search for other papers by Virginie Casamento in
Google Scholar
PubMed Close
,
Nadine Gautier Université Côte d’Azur, Inserm, CNRS, IRCAN, Nice, France

Search for other papers by Nadine Gautier in
Google Scholar
PubMed Close
,
Charlotte Hinault Université Côte d’Azur, CHU, Inserm, CNRS, IRCAN, Nice, France

Search for other papers by Charlotte Hinault in
Google Scholar
PubMed Close
,
Patricia Lebrun Université Côte d’Azur, Inserm, CNRS, IRCAN, Nice, France

Search for other papers by Patricia Lebrun in
Google Scholar
PubMed Close
,
Christophe Duranton Université Côte d’Azur, CNRS, LP2M, Nice, France

Search for other papers by Christophe Duranton in
Google Scholar
PubMed Close
,
Michel Tauc Université Côte d’Azur, CNRS, LP2M, Nice, France

Search for other papers by Michel Tauc in
Google Scholar
PubMed Close
,
Stéphane Dalle INSERM U1191, Institute of Functional Genomics (IGF), CNRS UMR5203, Montpellier University, Montpellier, France

Search for other papers by Stéphane Dalle in
Google Scholar
PubMed Close
,
Julie Kerr-Conte Translational Research for Diabetes, University of Lille, INSERM, CHRU Lille, Lille, France

Search for other papers by Julie Kerr-Conte in
Google Scholar
PubMed Close
,
François Pattou Translational Research for Diabetes, University of Lille, INSERM, CHRU Lille, Lille, France

Search for other papers by François Pattou in
Google Scholar
PubMed Close
,
Marc Prentki CRCHUM and Montreal Diabetes Research Center, Departments of Nutrition and Biochemistry and Molecular Medicine, University of Montreal, Montreal, Canada

Search for other papers by Marc Prentki in
Google Scholar
PubMed Close
, and
Emmanuel Van Obberghen Université Côte d’Azur, CNRS, LP2M, Nice, France
Université Côte d’Azur, CHU, Inserm, CNRS, IRCAN, Nice, France
Université Côte d’Azur, CHU, CNRS, LP2M, Nice, France

Search for other papers by Emmanuel Van Obberghen in
Google Scholar
PubMed Close

(disallowed genes) ( Quintens et al . 2008 , Pullen & Rutter 2013 ). Indeed, beta cells have a dedicated metabolism comprising a tightly regulated chain of elements from glucose sensors to a specialized exocytosis machinery. Glucose metabolism in beta cells

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0180
Volume/Issue:
Volume 244: Issue 1
Restricted access
Margaret K Hahn Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada
Department of Pharmacology, University of Toronto, Toronto, Ontario, Canada
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Banting & Best Diabetes Centre, Toronto, Ontario, Canada

Search for other papers by Margaret K Hahn in
Google Scholar
PubMed Close
,
Adria Giacca Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada
Banting & Best Diabetes Centre, Toronto, Ontario, Canada
Department of Physiology, University of Toronto, Toronto, Ontario, Canada

Search for other papers by Adria Giacca in
Google Scholar
PubMed Close
, and
Sandra Pereira Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Department of Physiology, University of Toronto, Toronto, Ontario, Canada

Search for other papers by Sandra Pereira in
Google Scholar
PubMed Close

Introduction Breakthroughs in metabolic research rely upon in vivo studies using animal models, usually rodents. Assessment of glucose metabolism in rodents is a key component of diabetes research. Although general guidelines for

Article Type:
Review Article
Collections:
Insulin resistance and type 2 diabetes mellitus
DOI:
https://doi.org/10.1530/JOE-23-0308
Volume/Issue:
Volume 260: Issue 3
Open access
Patricia Cristine Borck Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Patricia Cristine Borck in
Google Scholar
PubMed Close
,
Sarah Rickli Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Sarah Rickli in
Google Scholar
PubMed Close
,
Jean Franciesco Vettorazzi Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil
Union Education of Cascavel, UNIVEL, Cascavel, Paraná, Brazil

Search for other papers by Jean Franciesco Vettorazzi in
Google Scholar
PubMed Close
,
Thiago Martins Batista Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Thiago Martins Batista in
Google Scholar
PubMed Close
,
Antonio Carlos Boschero Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Antonio Carlos Boschero in
Google Scholar
PubMed Close
,
Elaine Vieira Postgraduate Program on Physical Education, Universidade Católica de Brasília-UCB, Distrito Federal, Brazil

Search for other papers by Elaine Vieira in
Google Scholar
PubMed Close
, and
Everardo Magalhães Carneiro Department of Structural and Functional Biology, Institute of Biology, University of Campinas/UNICAMP, Campinas, São Paulo, Brazil

Search for other papers by Everardo Magalhães Carneiro in
Google Scholar
PubMed Close

rhythms and glucose metabolism, instead of an enhanced phenotype, which could be associated at least in part with altered expression of Fgf21. Methods Animals All experimental procedures were approved in accordance with the Institutional

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-21-0133
Volume/Issue:
Volume 252: Issue 2
Restricted access
Yu Wu Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Yu Wu in
Google Scholar
PubMed Close
,
Tingting Wu Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Tingting Wu in
Google Scholar
PubMed Close
,
Jun Wu Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Jun Wu in
Google Scholar
PubMed Close
,
Lei Zhao Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Lei Zhao in
Google Scholar
PubMed Close
,
Qing Li Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Qing Li in
Google Scholar
PubMed Close
,
Zac Varghese Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Zac Varghese in
Google Scholar
PubMed Close
,
John F Moorhead Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by John F Moorhead in
Google Scholar
PubMed Close
,
Stephen H Powis Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Stephen H Powis in
Google Scholar
PubMed Close
,
Yaxi Chen Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Yaxi Chen in
Google Scholar
PubMed Close
, and
Xiong Z Ruan Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
Key Laboratory of Metabolism of Lipid and Glucose, John Moorhead Research Laboratory, Centre for Lipid Research, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China

Search for other papers by Xiong Z Ruan in
Google Scholar
PubMed Close

aggravated insulin resistance and glucose metabolism disorders in HFD-fed C57BL/6J mice The fasting glucose levels were unchanged in HFD-fed mice compared with NCD-fed mice ( Fig. 2 A and C). After glucose challenge, blood glucose concentration of HFD group

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0160
Volume/Issue:
Volume 219: Issue 3
Free access
Haijiang Wu Department of Pathology, Hebei Medical University, Shijiazhuang, China
Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China

Search for other papers by Haijiang Wu in
Google Scholar
PubMed Close
,
Xinna Deng Departments of Oncology & Immunotherapy, Hebei General Hospital, Shijiazhuang, China

Search for other papers by Xinna Deng in
Google Scholar
PubMed Close
,
Yonghong Shi Department of Pathology, Hebei Medical University, Shijiazhuang, China
Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China

Search for other papers by Yonghong Shi in
Google Scholar
PubMed Close
,
Ye Su Mathew Mailing Centre for Translational Transplantation Studies, Lawson Health Research Institute, London Health Sciences Centre, London, Ontario, Canada
Departments of Medicine and Pathology, University of Western Ontario, London, Ontario, Canada

Search for other papers by Ye Su in
Google Scholar
PubMed Close
,
Jinying Wei Department of Pathology, Hebei Medical University, Shijiazhuang, China
Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China

Search for other papers by Jinying Wei in
Google Scholar
PubMed Close
, and
Huijun Duan Department of Pathology, Hebei Medical University, Shijiazhuang, China
Key Laboratory of Kidney Diseases of Hebei Province, Shijiazhuang, China

Search for other papers by Huijun Duan in
Google Scholar
PubMed Close

therapy. In this review, we summarize the major findings on the function of PGC-1α in glucose metabolism and discuss its potential therapeutic applications for T2DM. The close correlation between PGC-1α polymorphisms and T2DM is also discussed in this

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0021
Volume/Issue:
Volume 229: Issue 3
Free access
Lars P Klieverik Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by Lars P Klieverik in
Google Scholar
PubMed Close
,
Ewout Foppen Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of
Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by Ewout Foppen in
Google Scholar
PubMed Close
,
Mariëtte T Ackermans Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by Mariëtte T Ackermans in
Google Scholar
PubMed Close
,
Mireille J Serlie Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by Mireille J Serlie in
Google Scholar
PubMed Close
,
Hans P Sauerwein Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by Hans P Sauerwein in
Google Scholar
PubMed Close
,
Thomas S Scanlan Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by Thomas S Scanlan in
Google Scholar
PubMed Close
,
David K Grandy Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by David K Grandy in
Google Scholar
PubMed Close
,
Eric Fliers Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by Eric Fliers in
Google Scholar
PubMed Close
, and
Andries Kalsbeek Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of
Laboratory of Endocrinology, Clinical Chemistry, Netherlands Institute for Neuroscience, Department of Physiology and Pharmacology, Departments of

Search for other papers by Andries Kalsbeek in
Google Scholar
PubMed Close

hypothalamus, regulates most of the processes affected by thyronamines (body temperature, cardiac function, and energy metabolism). Moreover, a principal role in regulating hepatic glucose metabolism has recently emerged for the hypothalamus ( Obici et al

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0043
Volume/Issue:
Volume 201: Issue 3
Free access
Gustavo Canul-Medina Unidad de Genética de la Nutrición, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/Instituto Nacional de Pediatría, Mexico City, Mexico

Search for other papers by Gustavo Canul-Medina in
Google Scholar
PubMed Close
,
Leticia Riverón-Negrete Unidad de Genética de la Nutrición, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/Instituto Nacional de Pediatría, Mexico City, Mexico

Search for other papers by Leticia Riverón-Negrete in
Google Scholar
PubMed Close
,
Karina Pastén-Hidalgo Cátedra CONACYT, Instituto Nacional de Pediatría, Mexico City, Mexico

Search for other papers by Karina Pastén-Hidalgo in
Google Scholar
PubMed Close
,
Paulina Morales-Castillo Unidad de Genética de la Nutrición, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/Instituto Nacional de Pediatría, Mexico City, Mexico

Search for other papers by Paulina Morales-Castillo in
Google Scholar
PubMed Close
,
Francisco García-Vázquez Laboratorio de Immunología y Alergia, Departamento de Análisis Clínicos y Estudios Especiales, Instituto Nacional de Pediatría, Mexico City, Mexico

Search for other papers by Francisco García-Vázquez in
Google Scholar
PubMed Close
, and
Cristina Fernandez-Mejia Unidad de Genética de la Nutrición, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/Instituto Nacional de Pediatría, Mexico City, Mexico

Search for other papers by Cristina Fernandez-Mejia in
Google Scholar
PubMed Close

for skeletal reconstruction. Glucose uptake is a determinant for osteoblast differentiation and bone formation ( Wei et al. 2015 ); however, little is known about glucose metabolism and pancreatic islet changes after weaning. Low concentrations of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-20-0184
Volume/Issue:
Volume 248: Issue 1
Restricted access
Kanta Kon Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Kanta Kon in
Google Scholar
PubMed Close
,
Hiroshi Tsuneki Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Hiroshi Tsuneki in
Google Scholar
PubMed Close
,
Hisakatsu Ito Department of Anesthesiology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Hisakatsu Ito in
Google Scholar
PubMed Close
,
Yoshinori Takemura Department of Anesthesiology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Yoshinori Takemura in
Google Scholar
PubMed Close
,
Kiyofumi Sato Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Kiyofumi Sato in
Google Scholar
PubMed Close
,
Mitsuaki Yamazaki Department of Anesthesiology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Mitsuaki Yamazaki in
Google Scholar
PubMed Close
,
Yoko Ishii Department of Pathology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Yoko Ishii in
Google Scholar
PubMed Close
,
Masakiyo Sasahara Department of Pathology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Masakiyo Sasahara in
Google Scholar
PubMed Close
,
Assaf Rudich Department of Clinical Biochemistry and Pharmacology, Ben-Gurion University of the Negev, Beer-Sheva, Israel

Search for other papers by Assaf Rudich in
Google Scholar
PubMed Close
,
Takahiro Maeda Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Takahiro Maeda in
Google Scholar
PubMed Close
,
Tsutomu Wada Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Tsutomu Wada in
Google Scholar
PubMed Close
, and
Toshiyasu Sasaoka Department of Clinical Pharmacology, University of Toyama, Sugitani, Toyama, Japan

Search for other papers by Toshiyasu Sasaoka in
Google Scholar
PubMed Close

and behavioral circadian misalignments in modern lifestyle, such as shift work and late eating, lead to dysregulation of glucose metabolism and increased risk of type 2 diabetes ( Cedernaes et al. 2015 , Qian et al. 2016 ). Intriguingly, one night

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0708
Volume/Issue:
Volume 243: Issue 1
Free access
K L Franko Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK

Search for other papers by K L Franko in
Google Scholar
PubMed Close
,
A J Forhead Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK

Search for other papers by A J Forhead in
Google Scholar
PubMed Close
, and
A L Fowden Department of Physiology, Development and Neuroscience, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK

Search for other papers by A L Fowden in
Google Scholar
PubMed Close

, little is known about the effects of commonly used control procedures, such as maternal saline or vehicle injection, on glucose metabolism of their offspring. The current study, therefore, compared the effects of maternal injection with dex or saline with

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0390
Volume/Issue:
Volume 204: Issue 3
Free access