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Jordan S F Chan
Jordan S F Chan
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Amanda A Greenwell
Amanda A Greenwell
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Christina T Saed
Christina T Saed
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Magnus J Stenlund
Magnus J Stenlund
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Indiresh A Mangra-Bala
Indiresh A Mangra-Bala
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Seyed Amirhossein Tabatabaei Dakhili
Seyed Amirhossein Tabatabaei Dakhili
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Kunyan Yang
Kunyan Yang
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Sally R Ferrari
Sally R Ferrari
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Farah Eaton
Farah Eaton
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Keshav Gopal
Keshav Gopal
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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John R Ussher
John R Ussher
Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Alberta, Canada
Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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Alberta Diabetes Institute, University of Alberta, Edmonton, Alberta, Canada
Cardiovascular Research Institute, University of Alberta, Edmonton, Alberta, Canada
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oxidation secondary to the stimulation of pyruvate dehydrogenase (PDH) activity ( Almutairi et al. 2021 ), the rate-limiting enzyme of glucose oxidation ( Patel et al. 2014 ). These actions on myocardial glucose oxidation appear to be indirectly mediated
L Zhao
L Zhao
Department of Medical Sciences, University Hospital, SE-751 85 Uppsala, Sweden
Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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Z Li
Z Li
Department of Medical Sciences, University Hospital, SE-751 85 Uppsala, Sweden
Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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M Kullin
M Kullin
Department of Medical Sciences, University Hospital, SE-751 85 Uppsala, Sweden
Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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L A H Borg
L A H Borg
Department of Medical Sciences, University Hospital, SE-751 85 Uppsala, Sweden
Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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F A Karlsson
F A Karlsson
Department of Medical Sciences, University Hospital, SE-751 85 Uppsala, Sweden
Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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Department of Medical Cell Biology, University of Uppsala, PO Box 571, SE-751 23 Uppsala, Sweden
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. To do this, confocal microscopy and quantitative immunohistochemistry were used in conjunction with measurements of islet net uptake of glucose and glucose oxidation. For comparison, we also examined the effects of stimulated insulin release on GLUT2
Ivonne Gisèle Makom Ndifossap
Ivonne Gisèle Makom Ndifossap
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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Francesca Frigerio
Francesca Frigerio
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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Marina Casimir
Marina Casimir
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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Florence Ngueguim Tsofack
Florence Ngueguim Tsofack
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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Etienne Dongo
Etienne Dongo
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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Pierre Kamtchouing
Pierre Kamtchouing
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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Théophile Dimo
Théophile Dimo
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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Pierre Maechler
Pierre Maechler
Department of Cell Physiology and Metabolism, Animal Biology and Physiology, Organic Chemistry, Faculty of Medicine, University of Geneva, 1 rue Michel-Servet, 1211 Geneva 4, Switzerland Departments of
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-secretion coupling, since glucose oxidation promotes ATP generation necessary for the triggering of exocytosis signals. Elevation of plasma insulin was reported in stem-bark-treated diabetic rats ( Dimo et al . 2007 ). Accordingly, it was of importance to
S K Richards
S K Richards
Richard Bright Renal Unit, Southmead Hospital, Bristol BS10 5NB, UK
Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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L E Parton
L E Parton
Richard Bright Renal Unit, Southmead Hospital, Bristol BS10 5NB, UK
Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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I Leclerc
I Leclerc
Richard Bright Renal Unit, Southmead Hospital, Bristol BS10 5NB, UK
Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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G A Rutter
G A Rutter
Richard Bright Renal Unit, Southmead Hospital, Bristol BS10 5NB, UK
Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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R M Smith
R M Smith
Richard Bright Renal Unit, Southmead Hospital, Bristol BS10 5NB, UK
Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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Henry Wellcome Signalling Laboratories and Department of Biochemistry, School of Medical Sciences, University Walk, University of Bristol, Bristol BS8 1TD, UK
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cellular (extractable) insulin content. [U- 14 C]Glucose oxidation Islets were preincubated for 30 min at 37 °C in KRBH supplemented with 3 mM glucose and 0.5% BSA (w/v). Triplicate groups of 100 islets were then placed
G. G. MURTHY
G. G. MURTHY
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R. R. MODESTO
R. R. MODESTO
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SUMMARY
The effects of luteinizing hormone releasing hormone (LH-RH) and thyrotrophin releasing hormone (TRH) on rabbit adipose tissue were studied. LH-RH increased [14C]glucose oxidation and incorporation into fatty acids and had lipolytic activity, at the same time decreasing [14C]glucose incorporation in glyceride—glycerol fractions. TRH had no significant effect on glucose oxidation or lipolysis but decreased [14C]fatty acid synthesis and [14C]glucose incorporation into glyceride—glycerol fractions.
Makiko Shimodahira
Makiko Shimodahira
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Shimpei Fujimoto
Shimpei Fujimoto
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Eri Mukai
Eri Mukai
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Yasuhiko Nakamura
Yasuhiko Nakamura
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Yuichi Nishi
Yuichi Nishi
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Mayumi Sasaki
Mayumi Sasaki
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Yuichi Sato
Yuichi Sato
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Hiroki Sato
Hiroki Sato
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Masaya Hosokawa
Masaya Hosokawa
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Kazuaki Nagashima
Kazuaki Nagashima
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Yutaka Seino
Yutaka Seino
Department of Diabetes and Clinical Nutrition, Kansai Electric Power Hospital, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
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Nobuya Inagaki
Nobuya Inagaki
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with 16.7 mM glucose. Effects of rapamycin on glucose utilization and glucose oxidation Glucose utilization was greater in islets incubated with 16.7 mM glucose than that in islets incubated with 2.8 mM glucose in both control (33.0±1.8, 2.8 mM glucose
Melissa A Davis
Melissa A Davis
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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Leticia E Camacho
Leticia E Camacho
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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Alexander L Pendleton
Alexander L Pendleton
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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Andrew T Antolic
Andrew T Antolic
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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Rosa I Luna-Ramirez
Rosa I Luna-Ramirez
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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Amy C Kelly
Amy C Kelly
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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Nathan R Steffens
Nathan R Steffens
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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Miranda J Anderson
Miranda J Anderson
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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Sean W Limesand
Sean W Limesand
School of Animal and Comparative Biomedical Sciences, University of Arizona, Tucson, Arizona, USA
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,f ) was calculated and used to determine the fetal glucose oxidation fraction and GOR (µmol/min) with the following equations: 14 CO 2 R p,f (dpm/min) = [ f × (a − v) 14 CO 2 concentration difference (dpm/mL)]; glucose oxidation fraction
Amanda J Genders
Amanda J Genders
Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia
Institute for Health and Sport (iHeS), Victoria University, Melbourne, Victoria, Australia
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Institute for Health and Sport (iHeS), Victoria University, Melbourne, Victoria, Australia
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Timothy Connor
Timothy Connor
Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia
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Shona Morrison
Shona Morrison
Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia
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Simon T Bond
Simon T Bond
Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia
Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia
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Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia
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Brian G Drew
Brian G Drew
Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia
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Peter J Meikle
Peter J Meikle
Baker Heart and Diabetes Institute, Melbourne, Victoria, Australia
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Kirsten F Howlett
Kirsten F Howlett
Institute for Physical Activity and Nutrition (IPAN) and School of Exercise and Nutrition Science and Deakin University, Geelong, Victoria, Australia
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Sean L McGee
Sean L McGee
Institute for Mental and Physical Health and Clinical Translation (iMPACT) and Metabolic Research Unit, School of Medicine, Deakin University, Geelong, Victoria, Australia
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in a number of metabolic alterations. These included increased whole-body glucose oxidation, altered transcriptional responses to fasting and refeeding and evidence of reduced capacity for gluconeogenesis. Furthermore, the expression of hepatic DN PKD
George Bikopoulos
George Bikopoulos
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Aurelio da Silva Pimenta
Aurelio da Silva Pimenta
Department of Laboratory Medicine and Pathobiology, School of Kinesiology and Health Science, Department of Physiology, Clinical Islet Transplant Program, Department of Agricultural, 1 King's College Circle, University of Toronto, Toronto, Canada M5S 1A8
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Simon C Lee
Simon C Lee
Department of Laboratory Medicine and Pathobiology, School of Kinesiology and Health Science, Department of Physiology, Clinical Islet Transplant Program, Department of Agricultural, 1 King's College Circle, University of Toronto, Toronto, Canada M5S 1A8
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Jonathan R Lakey
Jonathan R Lakey
Department of Laboratory Medicine and Pathobiology, School of Kinesiology and Health Science, Department of Physiology, Clinical Islet Transplant Program, Department of Agricultural, 1 King's College Circle, University of Toronto, Toronto, Canada M5S 1A8
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Sandy D Der
Sandy D Der
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Catherine B Chan
Catherine B Chan
Department of Laboratory Medicine and Pathobiology, School of Kinesiology and Health Science, Department of Physiology, Clinical Islet Transplant Program, Department of Agricultural, 1 King's College Circle, University of Toronto, Toronto, Canada M5S 1A8
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Rolando Bacis Ceddia
Rolando Bacis Ceddia
Department of Laboratory Medicine and Pathobiology, School of Kinesiology and Health Science, Department of Physiology, Clinical Islet Transplant Program, Department of Agricultural, 1 King's College Circle, University of Toronto, Toronto, Canada M5S 1A8
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Michael B Wheeler
Michael B Wheeler
Department of Laboratory Medicine and Pathobiology, School of Kinesiology and Health Science, Department of Physiology, Clinical Islet Transplant Program, Department of Agricultural, 1 King's College Circle, University of Toronto, Toronto, Canada M5S 1A8
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Maria Rozakis-Adcock
Maria Rozakis-Adcock
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systematically compared our own list of differentially expressed genes with a database of lists of differentially expressed genes that were derived from the published microarray data, and identified common expression patterns. Glucose oxidation Glucose oxidation
Kechun Tang
Kechun Tang
Department of Medicine, University of California, San Diego, La Jolla, California, USA
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Teresa Pasqua
Teresa Pasqua
Department of Medicine, University of California, San Diego, La Jolla, California, USA
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Angshuman Biswas
Angshuman Biswas
Department of Medicine, University of California, San Diego, La Jolla, California, USA
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Sumana Mahata
Sumana Mahata
Division of Biology & Biological Engineering, California Institute of Technology, Pasadena, California, USA
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Jennifer Tang
Jennifer Tang
Department of Medicine, University of California, San Diego, La Jolla, California, USA
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Alisa Tang
Alisa Tang
Department of Medicine, University of California, San Diego, La Jolla, California, USA
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Gautam K Bandyopadhyay
Gautam K Bandyopadhyay
Department of Medicine, University of California, San Diego, La Jolla, California, USA
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Amiya P Sinha-Hikim
Amiya P Sinha-Hikim
Charles Drew University of Medicine and Science, Los Angeles, California, USA
David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, USA
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David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, USA
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Nai-Wen Chi
Nai-Wen Chi
Department of Medicine, University of California, San Diego, La Jolla, California, USA
VA San Diego Healthcare System, San Diego, California, USA
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VA San Diego Healthcare System, San Diego, California, USA
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Nicholas J G Webster
Nicholas J G Webster
Department of Medicine, University of California, San Diego, La Jolla, California, USA
VA San Diego Healthcare System, San Diego, California, USA
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VA San Diego Healthcare System, San Diego, California, USA
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Angelo Corti
Angelo Corti
IRCCS San Raffaele Scientific Institute, San Raffaele Vita-Salute University, Milan, Italy
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Sushil K Mahata
Sushil K Mahata
Department of Medicine, University of California, San Diego, La Jolla, California, USA
VA San Diego Healthcare System, San Diego, California, USA
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VA San Diego Healthcare System, San Diego, California, USA
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running speed and endurance in the treadmill exercise in Chga -KO mice are due to the decrease in glucose uptake and glycolysis and defects in glucose oxidation caused by defective mitochondria. In addition, the lack of adaptation to endurance exercise
