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Christina Antza Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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Georgios Kostopoulos Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece

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Samiul Mostafa Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK

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Krishnarajah Nirantharakumar Institute of Applied Health Research, University of Birmingham, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

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Abd Tahrani Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
Department of Diabetes and Endocrinology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK
Centre of Endocrinology Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

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–12 Obesity (BMI):OR = 1.45 1.25, 1.67 66.2 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 28  Wu et al. 2014 10 164,016 ≥18 Self-reported Long sleep (>7 h) Normal (7 h) 1–12 Obesity (BMI):OR = 1.06 0.98, 1

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Daniela Leite de Oliveira Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Camila Hirotsu Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Sergio Tufik Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Monica Levy Andersen Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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and longer sleep latency were observed, as well as a reduction in NREM sleep ( Andersen & Tufik 2003 ). These results showed that pain was associated with intrinsic changes in sleep architecture. These findings have been confirmed in humans. A survey

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Galit Levi Dunietz Department of Neurology, Division of Sleep Medicine, University of Michigan, Ann Arbor, Michigan, USA

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Lucas J Tittle Department of Psychology, University of Michigan, Ann Arbor, Michigan, USA

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Sunni L Mumford Department of Biostatistics, Epidemiology and Informatics and Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Louise M O’Brien Department of Neurology, Division of Sleep Medicine, University of Michigan, Ann Arbor, Michigan, USA
Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan, USA

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Ana Baylin Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA

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Enrique F Schisterman Department of Biostatistics, Epidemiology and Informatics and Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

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Ronald D Chervin Department of Neurology, Division of Sleep Medicine, University of Michigan, Ann Arbor, Michigan, USA

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Larry J Young Center for Translational Social Neuroscience, Emory National Primate Research Center, Emory University, Atlanta, Georgia, USA
Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia, USA

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administration of OT to eight patients – women and men – with obstructive sleep apnea resulted in longer sleep time, increased subjective sleep satisfaction, and improved breathing during sleep ( Jain et al. 2017 ). Improved sleep was also reported in a double

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