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Katarzyna Czarzasta
Katarzyna Czarzasta
Department of Experimental and Clinical Physiology, Laboratory of Center for Preclinical Research, Medical University of Warsaw, Warszawa, Poland
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Luminita H Pojoga
Luminita H Pojoga
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women’s Hospital/Harvard Medical School, Boston, Massachusetts, USA
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suggest that targeting MR in both renal and extra-renal tissues may hold promise for the treatment of a range of diseases, such as hypertension, heart failure, and chronic inflammatory conditions, including metabolic disorders. Indeed, over the past
Isabel Huang-Doran
Isabel Huang-Doran
Metabolic Research Laboratories, Wolfson Brain Imaging Centre, Institute of Metabolic Science
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Alison Sleigh
Alison Sleigh
Metabolic Research Laboratories, Wolfson Brain Imaging Centre, Institute of Metabolic Science
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Justin J Rochford
Justin J Rochford
Metabolic Research Laboratories, Wolfson Brain Imaging Centre, Institute of Metabolic Science
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Stephen O'Rahilly
Stephen O'Rahilly
Metabolic Research Laboratories, Wolfson Brain Imaging Centre, Institute of Metabolic Science
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David B Savage
David B Savage
Metabolic Research Laboratories, Wolfson Brain Imaging Centre, Institute of Metabolic Science
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the relationship between obesity, insulin resistance and metabolic disease are incompletely understood, and the contributory genes are poorly defined. A powerful approach to this daunting problem – and one that is potentially applicable to any complex
Hong Lan
Hong Lan
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Galya Vassileva
Galya Vassileva
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Aaron Corona
Aaron Corona
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Li Liu
Li Liu
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Hana Baker
Hana Baker
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Andrei Golovko
Andrei Golovko
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Susan J Abbondanzo
Susan J Abbondanzo
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Weiwen Hu
Weiwen Hu
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Shijun Yang
Shijun Yang
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Yun Ning
Yun Ning
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Robert A Del Vecchio
Robert A Del Vecchio
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Frederique Poulet
Frederique Poulet
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Maureen Laverty
Maureen Laverty
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Eric L Gustafson
Eric L Gustafson
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Joseph A Hedrick
Joseph A Hedrick
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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Timothy J Kowalski
Timothy J Kowalski
Cardiovascular and Metabolic Disease Research, Drug Safety,, Departments of
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and glucose homeostasis under conditions of metabolic stress such as diet-induced obesity. We carried out a systematic characterization of independently generated Gpr119 −/− mice on the C57BL/6J background. Our results demonstrate that GPR119 is not
Sheree D Martin
Sheree D Martin
Metabolic Reprogramming Laboratory, Metabolic Research Unit, School of Medicine and Centre for Molecular and Medical Research, Deakin University, Geelong, Australia
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Sean L McGee
Sean L McGee
Metabolic Reprogramming Laboratory, Metabolic Research Unit, School of Medicine and Centre for Molecular and Medical Research, Deakin University, Geelong, Australia
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-menopausal women and remains evident when controlling for the confounding effects of obesity ( Xue & Michels 2007 ). This suggests important interactions between key hormones and metabolic alterations in type 2 diabetes that predispose to the development of breast
Fabio Arturo Iannotti
Fabio Arturo Iannotti
Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, Pozzuoli, Campania, Italy
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Vincenzo Di Marzo
Vincenzo Di Marzo
Director, Joint International Research Unit for the Chemical and Biomolecular Study of the Microbiome in Metabolic Health and Nutrition (JIRU-MicroMeNu) between the Consiglio Nazionale delle Ricerche (CNR, Institute of Biomolecular Chemistry) and Université Laval, Naples, Campania, Italy
Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Department of Medicine, Faculty of Medicine and School of Nutrition, Faculty of Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Québec City, Canada
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Canada Excellence Research Chair on the Microbiome-Endocannabinoidome Axis in Metabolic Health (CERC-MEND), Department of Medicine, Faculty of Medicine and School of Nutrition, Faculty of Agricultural and Food Sciences, CRIUCPQ, INAF and Centre NUTRISS, Université Laval, Québec City, Canada
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ideal control of nutrient processing necessary for metabolic health. This concept was supported in particular by laboratory experiments in which a ‘transplant’ of the faecal microbiome of obese individuals (human or mice) to healthy mice could transfer
Marta Lantero Rodriguez
Marta Lantero Rodriguez
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Maaike Schilperoort
Maaike Schilperoort
Department of Medicine, Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Inger Johansson
Inger Johansson
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Elin Svedlund Eriksson
Elin Svedlund Eriksson
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Vilborg Palsdottir
Vilborg Palsdottir
Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Jan Kroon
Jan Kroon
Department of Medicine, Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Marcus Henricsson
Marcus Henricsson
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Sander Kooijman
Sander Kooijman
Department of Medicine, Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Mia Ericson
Mia Ericson
Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Jan Borén
Jan Borén
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Claes Ohlsson
Claes Ohlsson
Center for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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John-Olov Jansson
John-Olov Jansson
Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Malin C Levin
Malin C Levin
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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Patrick C N Rensen
Patrick C N Rensen
Department of Medicine, Division of Endocrinology and Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands
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Åsa Tivesten
Åsa Tivesten
Wallenberg Laboratory for Cardiovascular and Metabolic Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
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al. 2005 , Yanase et al. 2008 ). It is not known whether androgens modulate BAT activity in vivo and through which pathway(s) such an effect could be mediated. In the current study, we aimed to clarify the role of testosterone in metabolic BAT
Zhiguo Liu
Zhiguo Liu
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Chun Yan Lim
Chun Yan Lim
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Michelle Yu-Fah Su
Michelle Yu-Fah Su
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Stephanie Li Ying Soh
Stephanie Li Ying Soh
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Guanghou Shui
Guanghou Shui
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Markus R Wenk
Markus R Wenk
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Kevin L Grove
Kevin L Grove
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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George K Radda
George K Radda
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Weiping Han
Weiping Han
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Xiaoqiu Xiao
Xiaoqiu Xiao
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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Laboratory of Lipid and Glucose Metabolism, Laboratory of Metabolic Medicine, Division of Neuroscience, Department of Biochemistry, The First Affiliated Hospital of Chongqing Medical University, 1 Youyi Road, Yuzhong District, Chongqing 400016, People's Republic of China
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metabolic syndrome several decades later ( Armitage et al . 2004 , Toschke et al . 2004 , Patel & Srinivasan 2010 ). Therefore, both pre- and postnatal nutrition have significant effects on the long-term regulation of body weight and energy homeostasis
Karsten Suhre
Karsten Suhre
Department of Physiology and Biophysics, Institute of Bioinformatics and Systems Biology, Qatar Foundation – Education City, Weill Cornell Medical College – Qatar, PO Box 24144, Doha, Qatar
Department of Physiology and Biophysics, Institute of Bioinformatics and Systems Biology, Qatar Foundation – Education City, Weill Cornell Medical College – Qatar, PO Box 24144, Doha, Qatar
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Department of Physiology and Biophysics, Institute of Bioinformatics and Systems Biology, Qatar Foundation – Education City, Weill Cornell Medical College – Qatar, PO Box 24144, Doha, Qatar
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Introduction Metabolic profiling, or metabolomics, aims at determining all relevant small molecules (metabolites) in a biological sample ( Pauling et al . 1971 ). Recent technology advances have allowed the characterization of hundreds of
Dan Wang
Dan Wang
Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China
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Chu-Dan Liu
Chu-Dan Liu
Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China
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Meng-Li Tian
Meng-Li Tian
Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China
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Cheng-Quan Tan
Cheng-Quan Tan
Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China
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Gang Shu
Gang Shu
Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China
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Qing-Yan Jiang
Qing-Yan Jiang
Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China
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Lin Zhang
Lin Zhang
Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China
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Yu-Long Yin
Yu-Long Yin
Guangdong Provincial Key Laboratory of Animal Nutrition Control, National Engineering Research Center for Breeding Swine Industry, Institute of Subtropical Animal Nutrition and Feed, College of Animal Science, South China Agricultural University, Guangzhou, Guangdong, China
Key Laboratory of Agro-Ecological Processes in Subtropical Region, Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan, China
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Key Laboratory of Agro-Ecological Processes in Subtropical Region, Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan, China
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Introduction Metabolic disorders such as obesity and type 2 diabetes have become major threats to human health worldwide ( Franks et al. 2016 ). It is well recognized that dietary fiber intervention is one of the most efficient strategies
Elisa Villalobos
Elisa Villalobos
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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Allende Miguelez-Crespo
Allende Miguelez-Crespo
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Ruth A Morgan
Ruth A Morgan
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Scotland’s Rural College, The Roslin Institute, Easter Bush Campus, United Kingdom
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Scotland’s Rural College, The Roslin Institute, Easter Bush Campus, United Kingdom
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Lisa Ivatt
Lisa Ivatt
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Mhairi Paul
Mhairi Paul
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Joanna P Simpson
Joanna P Simpson
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Natalie Z M Homer
Natalie Z M Homer
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Dominic Kurian
Dominic Kurian
The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush Campus, Edinburgh, United Kingdom
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Judit Aguilar
Judit Aguilar
The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush Campus, Edinburgh, United Kingdom
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Rachel A Kline
Rachel A Kline
The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush Campus, Edinburgh, United Kingdom
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Thomas M Wishart
Thomas M Wishart
The Roslin Institute, Royal (Dick) School of Veterinary Studies, College of Medicine and Veterinary Medicine, University of Edinburgh, Easter Bush Campus, Edinburgh, United Kingdom
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Nicholas M Morton
Nicholas M Morton
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Centre for Systems Health and Integrated Metabolic Research, Nottingham Trent University, Nottingham, United Kingdom
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Centre for Systems Health and Integrated Metabolic Research, Nottingham Trent University, Nottingham, United Kingdom
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Roland H Stimson
Roland H Stimson
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Ruth Andrew
Ruth Andrew
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Brian R Walker
Brian R Walker
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom
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Mark Nixon
Mark Nixon
University/British Heart Foundation Centre for Cardiovascular Science, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom
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Introduction Glucocorticoids are required to maintain glucose and lipid homeostasis in times of physiological stress, ensuring an adequate fuel supply for the body ( Kuo et al. 2015 ). In key metabolic tissues such as adipose tissue
