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120 1265 –1282. Gordon WR , Vardar-Ulu D, Histen G, Sanchez-Irizarry C, Aster JC & Blacklow SC 2007 Structural basis for autoinhibition of Notch. Nature Structural and Molecular Biology 14 295 –300
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ABSTRACT
Advances in techniques in molecular biology have facilitated the research into endogenous opioids and related peptides in several ways. The organization and expression of genes and the primary structure of three precursor proteins of opioid peptides have been elucidated. These studies predicted the presence of potentially bioactive peptides, which has been confirmed by later studies. Advances in techniques in protein chemistry have helped to elucidate the distribution and molecular forms of endogenous opioids and related peptides in the body, and the processing of precursor proteins. Studies on the function of these peptides have shown a broad spectrum of actions. Leumorphin, a newly identified peptide, has been shown to exhibit unique biological activities. In spite of extensive studies, the physiological and pathophysiological significance of opioid peptide systems are not yet completely understood. This is mainly due to the paucity of our knowledge about opioid receptors. Further studies on the subtypes of opioid receptors will help to elucidate all aspects of the function of endogenous opioids and related peptides.
J. Endocr. (1985) 107, 147–157
Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, Verona, Italy
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Department of Diagnostics and Public Health, Section of Pathology, University and Hospital Trust of Verona, Verona, Italy
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publication of the ICGC group results and will then discuss the contribution of the latter to the building of a more complete picture of the molecular biology of PanNETs. Finally, we will give an overview of the open questions and expected developments after
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family by phylogenetic studies . Molecular Biology and Evolution 24 78 – 79 . Kontula KK Torkkeli TK Bardin CW Jänne OA 1984 Androgen induction of ornithine decarboxylase mRNA as studied by complementary DNA . PNAS 81 731 – 735 . Kubovcanova L
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Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
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Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
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Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
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Department of Pulmonary and Critical Care Medicine, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
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Department of Pulmonary and Critical Care Medicine, the Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China
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Respiratory Cell and Molecular Biology 50 1156 – 1165 . ( https://doi.org/10.1165/rcmb.2013-0268oc ) Itoh N & Ornitz DM 2004 Evolution of the Fgf and Fgfr gene families . Trends in Genetics 20 563 – 569 . ( https://doi.org/10.1016/j.tig.2004
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Introduction
Rickets has long been of interest in Britain, since the original monographs of Whistler and of Glisson, Bate and Regemorter. Both of those works were in Latin but Whistler rapidly had an English translation made which shows that the title of his thesis was 'Inaugural Medical Disputation of the Children's Disease of the English which the inhabitants idiomatically called 'the rickets', which, God aiding him, Daniel Whistler, Eastern Anglo-Saxon, with the authority of the most noble and magnificent rector Dr Johannes Polyander a Kerkchoven, doctor of Holy Theology and Principle Professor of the same faculty in the illustrious Academy of Leyden in Holland propounds there for dispute for the Degree of Doctor and its entailed high privileges in Medicine on the 18th day of October at the accustomed time and place'. His thesis was printed in 1645, a few years before Glisson's book (1650), but even so
Department of Sciences, University of British Columbia, Vancouver, Canada
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Department of Medical Genetics, University of British Columbia, Vancouver, Canada
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Department of Microbiology & Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, Canada
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Department of Medical Genetics, University of British Columbia, Vancouver, Canada
Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, Canada
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the development of a deeper understanding of the molecular biology that underlies thyroid function and provides important contextual epigenetic information for comparison and integration into future studies. Supplementary data This is linked to
Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Campusvej 55, DK-5230 Odense M, Denmark
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Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Campusvej 55, DK-5230 Odense M, Denmark
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Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Campusvej 55, DK-5230 Odense M, Denmark
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, Lecointre G, Mercier B, Cramb G & Ferec C 2001 A combined analysis of the cystic fibrosis transmembrane conductance regulator: implications for structure and disease models. Molecular Biology and Evolution 18 1771 –1788
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and function. Journal of Steroid Biochemistry and Molecular Biology 69 307 –313. Castillo L , Ajami A, Branch S, Chapman TE, Yu YM, Burke JF & Young VR 1994 Plasma arginine kinetics in adult man: response to an
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Steroid Biochemistry and Molecular Biology 72 35 –46. Ojanotko-Harri A , Forssell H, Laine M, Hurttia H, Blauer M & Tuohimaa P 1992 Immunohistochemical detection of androgen receptors in human oral mucosa. Archives of
