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XueJing Zhang, JianHua Li, JiaLi Liu, HaoShu Luo, KeMian Gou and Sheng Cui

luteal cells and CL tissues and the effect of PGF 2 α on the apoptosis of luteal cells is mediated by the Slit/Robo interaction. Materials and methods Reagents Rabbit IgG anti-Slit2 polyclonal antibodies and mouse IgM anti-Robo1 MABs were

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Dang-Dang Li, Ying-Jie Gao, Xue-Chao Tian, Zhan-Qing Yang, Hang Cao, Qiao-Ling Zhang, Bin Guo and Zhan-Peng Yue

. 1998 , Saito et al . 2007 ). During the gestation period, I do was strongly expressed in the mouse concepti and placenta from days 8.5 to 12.5 of post-coitus ( Suzuki et al . 2001 , Minatogawa et al . 2003 ). Unexpectedly, tryptophan

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Cassandra C Yap, Michaela D Wharfe, Peter J Mark, Brendan J Waddell and Jeremy T Smith

mouse ( Wharfe et al. 2016 ), and Wharfe and coworkers have also previously demonstrated that clock gene rhythms in the rat liver are altered by pregnancy ( Wharfe et al. 2011 ). Additionally, despite the high estradiol levels during pregnancy, the

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Elizabeth S Barrie, Mels Lodder, Paul H Weinreb, Jill Buss, Amer Rajab, Christopher Adin, Qing-Sheng Mi and Gregg A Hadley

per week using a Bayer Glucometer Elite. A mouse was deemed diabetic after two consecutive BG readings of >250 mg/dl. Mice were housed in accordance with the Ohio State University's requirements and regulations for animal care and use. Mice were

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Gabriele E Mattos, Jan-Michael Heinzmann, Stefanie Norkowski, Jean-Christophe Helbling, Amandine M Minni, Marie-Pierre Moisan and Chadi Touma

types of acute or chronic stressors, CBG expression was found to be downregulated, thereby increasing free GC levels ( Neufeld et al . 1994 , Fleshner et al . 1995 , Spencer et al . 1996 ). Recently, the analysis of a mouse model of targeted CBG

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Claudia E Robert-Cooperman, Grace C Dougan, Shari L Moak, Mark G Athanason, Melanie N Kuehl, Harris Bell-Temin, Stanley M Stevens Jr and Brant R Burkhardt

context of the observed in vivo tissue distribution of PANDER. Therefore, to further elucidate the physiologic role of pancreas-secreted PANDER in vivo , our laboratory has created and phenotyped the only transgenic mouse model (PANDER transgenic, PANTG

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Bernard Freudenthal, John Logan, Sanger Institute Mouse Pipelines, Peter I Croucher, Graham R Williams and J H Duncan Bassett

identification of extreme skeletal phenotypes in mutant mouse lines that carry single-gene knockouts representing all the known protein-coding genes. This approach has been made possible by the International Knockout Mouse Consortium (IKMC), whose aim is to

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Manuel D Gahete, Juan M Jiménez-Vacas, Emilia Alors-Pérez, Vicente Herrero-Aguayo, Antonio C Fuentes-Fayos, Sergio Pedraza-Arévalo, Justo P Castaño and Raúl M Luque

high-scale translational and clinical studies. In this scenario, mouse models have emerged as a powerful and essential tool in basic and translational tumor biology research ( Day et al. 2015 , Gengenbacher et al. 2017 , Kersten et al. 2017

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Harleen Kaur, Beverly S Muhlhausler, Pamela Su-Lin Sim, Amanda J Page, Hui Li, Maria Nunez-Salces, Georgia S Clarke, Lili Huang, Rebecca L Wilson, Johannes D Veldhuis, Chen Chen, Claire T Roberts and Kathryn L Gatford

generate pulsatile GH secretion from the anterior pituitary, is one possible candidate. In mouse stomach, the endoproteolytic processing of the ghrelin molecule from its precursor (proghrelin) into mature ghrelin is facilitated by the enzyme prohormone

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M J Devlin, D J Brooks, C Conlon, M van Vliet, L Louis, C J Rosen and M L Bouxsein

growing mice to model human energy restriction ( Devlin et al . 2010 ). Materials and methods Mouse model and experimental protocol This study used female C57Bl/6J mice (Jackson Laboratories), studied from 5 to 10 weeks of age. Mice were