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Mercedes Lombarte, Brenda L Fina, Maela Lupo, Marília A Buzalaf, and Alfredo Rigalli

glucose levels and normal values of insulin levels were observed, although they received NaF. Normalization of the HOMA–IR index in the Exercise group could also be due to the lower levels of fluoride in the plasma. Physical exercise stimulates bone

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Daniele Leão Ignacio, Rodrigo Soares Fortunato, Diego Silvestre, Leonardo Matta, Andressa Lima de Vansconcelos, Denise Pires Carvalho, Antonio Galina, João Pedro Werneck-de-Castro, and João Paulo Cavalcanti-de-Albuquerque

and could explain the fat gain observed in this model. Physical exercise is a non-pharmacological approach to treat metabolic diseases ( Colberg et al. 2010 ). Exercise-induced adaptations slow down age-related muscle-function decline, including

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Ana P Pinto, Alisson L da Rocha, Eike B Kohama, Rafael C Gaspar, Fernando M Simabuco, Fabiani G Frantz, Leandro P de Moura, José R Pauli, Dennys E Cintra, Eduardo R Ropelle, Ellen C de Freitas, and Adelino S R da Silva

adequate function and survival of the organism, becoming harmful when chronically engaged ( Hotamisligil 2010 ). The practice of intense physical exercise increases plasma IL-6 concentration ( Wojewoda et al . 2014 , 2015 ). Also, IL-6 has been

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Hyo Youl Moon, Parkyong Song, Cheol Soo Choi, Sung Ho Ryu, and Pann-Ghill Suh

impact of physical exercise . Cellular and Molecular Life Sciences 63 1393 – 1409 . ( doi:10.1007/s00018-006-6600-y ) Lazo M Clark JM 2008 The epidemiology of nonalcoholic fatty liver disease: a global perspective . Seminars in Liver Disease

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Mirian A Kurauti, José M Costa-Júnior, Sandra M Ferreira, Gustavo J dos Santos, André O P Protzek, Tarlliza R Nardelli, Luiz F de Rezende, and Antonio C Boschero

insulinemia in physical exercised DIO mice. Materials and methods Animals and diet Male C57BL/6 mice from the State University of Campinas Facilities were maintained on a 12h light:12h darkness cycle at 20–21°C with controlled humidity during the

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Erica Sarchielli, Paolo Comeglio, Sandra Filippi, Ilaria Cellai, Giulia Guarnieri, Daniele Guasti, Elena Rapizzi, Giulia Rastrelli, Daniele Bani, Gabriella Vannelli, Linda Vignozzi, Annamaria Morelli, and Mario Maggi

are less prone to perform physical exercise. Given the well-known trophic role of testosterone on skeletal muscle (SkM) mass, in this study, we extended the previous findings with the aim of analysing the effects of HFD on SkM composition and

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Hari K Somineni, Gregory P Boivin, and Khalid M Elased

similar and additional information. One study demonstrated improved glucose homeostasis following exercise training in high-fat-fed mice via upregulation of plasma irisin ( Bostrom et al . 2012 ). Physical exercise also attenuated albuminuria, proteinuria

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LIISI ADAMSON, W. M. HUNTER, O. O. OGUNREMI, I. OSWALD, and I. W. PERCY-ROBB

SUMMARY

The effects of strenuous daytime physical exercise were examined in 12 healthy male volunteers. All-night electrophysiological recordings were made and blood was sampled during sleep by indwelling venous catheter.

Plasma growth hormone levels were significantly increased after exercise but the sleep electroencephalographic patterns of nights after exercise did not differ significantly from those of control nights. Plasma corticosteroids were decreased after exercise. It is suggested that higher levels of growth hormone are consistent with reparative processes during sleep.

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Rodrigo Martins Pereira, Kellen Cristina da Cruz Rodrigues, Marcella Ramos Sant’Ana, Guilherme Francisco Peruca, Ana Paula Morelli, Fernando M Simabuco, Adelino S R da Silva, Dennys Esper Cintra, Eduardo Rochete Ropelle, José Rodrigo Pauli, and Leandro Pereira de Moura

hyperinsulinemia in obese mice, as well as improving insulin signaling. Interestingly, these data were accompanied by a reduction in hepatic PC levels ( Muñoz et al. 2018 ). On the other hand, the effects of strength physical exercise and body weight changes on

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Mariana Rosolen Tavares, Renata Frazao, and Jose Donato Jr

particularly evident in situations of metabolic stress, such as hypoglycemia ( Roth et al. 1963 ), prolonged food deprivation ( Zhao et al. 2010 ), physical exercise ( Veldhuis et al. 2015 ), and even pregnancy ( Gatford et al. 2017 ), which is a