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Rebecca M Reynolds and Adrienne Gordon

. 2017 ). Obesity impacts on health of women across their reproductive lifespan with adverse effects on not only fertility and short-term complications of pregnancy, but also on longer-term health outcomes for both women and their children. Here, we

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Michaela D Wharfe, Peter J Mark, Caitlin S Wyrwoll, Jeremy T Smith, Cassandra Yap, Michael W Clarke and Brendan J Waddell

Introduction Maternal physiological adaptations are central to pregnancy success, balancing fetal and placental demands with the maintenance of maternal homeostasis. Among these maternal adaptations, enhanced activity of the hypothalamic

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Derek S Boeldt, Mary A Grummer, Ronald R Magness and Ian M Bird

Introduction Pregnancy is a time of dramatic vascular adaptation. Through initial angiogenesis and then sustained vasodilation, the pregnant uterus achieves the biggest drop in vascular resistance of any organ system. This in turn promotes a

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Cassandra C Yap, Michaela D Wharfe, Peter J Mark, Brendan J Waddell and Jeremy T Smith

mouse ( Wharfe et al. 2016 ), and Wharfe and coworkers have also previously demonstrated that clock gene rhythms in the rat liver are altered by pregnancy ( Wharfe et al. 2011 ). Additionally, despite the high estradiol levels during pregnancy, the

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Ankana Ganguly, Jennifer A Tamblyn, Sarah Finn-Sell, Shiao-Y Chan, Melissa Westwood, Janesh Gupta, Mark D Kilby, Stephane R Gross and Martin Hewison

addition to facilitating a good maternal blood supply for nutrition–waste exchange and orchestrating endocrine mediators of pregnancy to maintain maternal physiological changes for an optimal environment for fetal development, the placenta also acts to

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Jackson Nteeba, Kaiyu Kubota, Wenfang Wang, Hao Zhu, Jay L Vivian, Guoli Dai and Michael J Soares

Introduction Glucose intolerance during pregnancy, known as gestational diabetes mellitus (GDM), is one of the most common pregnancy complications and affects nearly 17% of all pregnancies globally and ~7% in the United States ( Newbern

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Jacqueline M Wallace

:// ). Nevertheless, pregnancy during adolescence still accounts for an estimated 11% of all births worldwide with more than 95% of these occurring in developing countries ( ). The antecedents of

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Dang-Dang Li, Ying-Jie Gao, Xue-Chao Tian, Zhan-Qing Yang, Hang Cao, Qiao-Ling Zhang, Bin Guo and Zhan-Peng Yue

tract, and female reproductive tract ( Stone & Darlington 2002 , Doherty et al . 2011 ). In mammals, most of tryptophan was metabolized along the kynurenine pathway and tryptophan metabolism was closely correlated with pregnancy ( Stone & Darlington

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Yuhui Liu, Le Zhang, Jing Li, Zhongyan Shan and Weiping Teng

damaging for neurodevelopment of the fetus throughout pregnancy ( Morreale et al . 2004 ) and results in permanent and profound effects on neurological functions that contribute to cognitive and neurological impairments ( Bernal et al . 2003 , Tremont

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Elisa Keating, Ana Correia-Branco, João R Araújo, Manuela Meireles, Rita Fernandes, Luísa Guardão, João T Guimarães, Fátima Martel and Conceição Calhau

uncertainty about potential health hazards. In addition, the WHO currently recommends supplementation with 0.4 mg/day of FA to women during pregnancy and the first 3 months post partum . As a result of all these public health policies, it is an emerging