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Rubén Marín-Juez, Susanne Jong-Raadsen, Shuxin Yang and Herman P Spaink

type 6 ( ptpn6 ). PTPN6 (also known as SHP1) is expressed mainly in hematopoietic cells ( Yi et al . 1992 ) and has been described as an important negative regulator of immune signaling pathways ( An et al . 2008 , Croker et al . 2008 ). In addition

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Vanesa Jiménez-Amilburu, Susanne Jong-Raadsen, Jeroen Bakkers, Herman P Spaink and Rubén Marín-Juez

insulin resistance and immune suppression via Ptpn6/Shp1 in zebrafish . Journal of Endocrinology 222 229 – 241 . ( doi:10.1530/JOE-14-0178 ) Mootha VK Lindgren CM Eriksson KF Subramanian A Sihag S Lehar J Puigserver P Carlsson E