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Gemma Llauradó, Victòria Ceperuelo-Mallafré, Carme Vilardell, Rafael Simó, Pilar Gil, Albert Cano, Joan Vendrell, and José-Miguel González-Clemente

tissue accumulation of AGEs ( Meerwaldt et al . 2004 ). The gold standard for measuring central AS is aortic pulse wave velocity (aPWV). Higher aPWV is reflective of AS. AGEs have been associated with an increase in aPWV in healthy individuals ( Semba

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Daniel M Kelly and T Hugh Jones

-sectional study of older men ( Dockery et al . 2003 a ). This is further supported by the evidence that patients with prostate cancer undergoing ADT develop arterial stiffness within 3 months, as measured by the pulse-wave velocity ( Smith et al . 2001