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Ashley I Taylor SAAD Centre for Pharmacy and Diabetes, School of Biomedical Sciences Research Institute, University of Ulster, Coleraine BT52 1SA, UK

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Nigel Irwin SAAD Centre for Pharmacy and Diabetes, School of Biomedical Sciences Research Institute, University of Ulster, Coleraine BT52 1SA, UK

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Aine M McKillop SAAD Centre for Pharmacy and Diabetes, School of Biomedical Sciences Research Institute, University of Ulster, Coleraine BT52 1SA, UK

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Steven Patterson SAAD Centre for Pharmacy and Diabetes, School of Biomedical Sciences Research Institute, University of Ulster, Coleraine BT52 1SA, UK

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Peter R Flatt SAAD Centre for Pharmacy and Diabetes, School of Biomedical Sciences Research Institute, University of Ulster, Coleraine BT52 1SA, UK

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Victor A Gault SAAD Centre for Pharmacy and Diabetes, School of Biomedical Sciences Research Institute, University of Ulster, Coleraine BT52 1SA, UK

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physiology have focused on anorectic and satiety actions, because of its discovery in the hypothalamus ( Alexiou et al . 1998 ). Thus, a concentration-dependent inhibitory effect on food intake has since been demonstrated in chicks and rats ( Cline et al

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-10-0085
Volume/Issue:
Volume 207: Issue 1
Free access
Catherine Gibbons Biopsychology Group, Institute of Psychological Sciences, University Leeds, Leeds LS2 9JZ, UK

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Graham Finlayson Biopsychology Group, Institute of Psychological Sciences, University Leeds, Leeds LS2 9JZ, UK

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Michelle Dalton Biopsychology Group, Institute of Psychological Sciences, University Leeds, Leeds LS2 9JZ, UK

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Phillipa Caudwell Biopsychology Group, Institute of Psychological Sciences, University Leeds, Leeds LS2 9JZ, UK

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John E Blundell Biopsychology Group, Institute of Psychological Sciences, University Leeds, Leeds LS2 9JZ, UK

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-living environment. Appetite terminology: satiety and satiation Food consumption is episodic; it occurs in discrete bouts a certain number of times each day giving rise to a variety of patterns. In laboratory research, a single eating episode is often the focus of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-14-0020
Volume/Issue:
Volume 222: Issue 2
Free access
Ryan A Lafferty Diabetes Research Centre, Schools of Biomedical Sciences and Pharmacy & Pharmaceutical Sciences, Ulster University, Coleraine, Northern Ireland, UK

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Peter R Flatt Diabetes Research Centre, Schools of Biomedical Sciences and Pharmacy & Pharmaceutical Sciences, Ulster University, Coleraine, Northern Ireland, UK

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Victor A Gault Diabetes Research Centre, Schools of Biomedical Sciences and Pharmacy & Pharmaceutical Sciences, Ulster University, Coleraine, Northern Ireland, UK

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Nigel Irwin Diabetes Research Centre, Schools of Biomedical Sciences and Pharmacy & Pharmaceutical Sciences, Ulster University, Coleraine, Northern Ireland, UK

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being implicated in the modulation of food intake and satiety, particularly in the arcuate, paraventricular, and dorsomedial nuclei regions ( Adriaenssens et al. 2019 , Samms et al. 2020 ). In addition, GIPR signalling is also demonstrated within

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-23-0339
Volume/Issue:
Volume 262: Issue 2
Open access
L van Bloemendaal
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J S ten Kulve
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S E la Fleur Diabetes Centre, Department of Endocrinology and Metabolism, VU University Medical Centre, PO Box 7057, 1007 MB Amsterdam, The Netherlands

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R G Ijzerman
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M Diamant
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the gut, pancreas, and adipose tissue, convey information on hunger and/or satiety to the brain. Gut-derived hormones, such as the orexigenic hormone ghrelin and the prandially secreted anorexigenic hormones cholecystokinin (CCK), peptide YY (PYY

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-13-0414
Volume/Issue:
Volume 221: Issue 1
Free access
Katie Wynne Endocrine Unit, Imperial College Faculty of Medicine, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK

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Sarah Stanley Endocrine Unit, Imperial College Faculty of Medicine, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK

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Barbara McGowan Endocrine Unit, Imperial College Faculty of Medicine, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK

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Steve Bloom Endocrine Unit, Imperial College Faculty of Medicine, Hammersmith Hospital, Du Cane Road, London W12 ONN, UK

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the hypothalamic nuclei initially suggested roles for the ventromedial nucleus as a ‘satiety centre’ and the lateral hypothalamic nucleus (LHA) as a ‘hunger centre’ ( Stellar 1994 ). However, rather than specific hypothalamic nuclei controlling energy

Article Type:
Other
DOI:
https://doi.org/10.1677/joe.1.05866
Volume/Issue:
Volume 184: Issue 2
Free access
Harman S Mattu Division of Metabolic and Vascular Health, University of Warwick Medical School, Gibbet Hill Road, Coventry CV4 7AL, UK

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Harpal S Randeva Division of Metabolic and Vascular Health, University of Warwick Medical School, Gibbet Hill Road, Coventry CV4 7AL, UK

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WAT ( Beltowski 2006 a ). In the obese, there are high concentrations of leptin – directly due to increased adipose tissue mass. This paradox of raised levels of this satiety molecule in obesity may be explained in part by the resistance of leptin via

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-12-0232
Volume/Issue:
Volume 216: Issue 1
Free access
Maureen J Charron Departments of Biochemistry, Obstetrics and Gynecology and Women's Health, Medicine, Department of Pediatrics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, F312, Bronx, New York 10461, USA
Departments of Biochemistry, Obstetrics and Gynecology and Women's Health, Medicine, Department of Pediatrics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, F312, Bronx, New York 10461, USA
Departments of Biochemistry, Obstetrics and Gynecology and Women's Health, Medicine, Department of Pediatrics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, F312, Bronx, New York 10461, USA

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Patricia M Vuguin Departments of Biochemistry, Obstetrics and Gynecology and Women's Health, Medicine, Department of Pediatrics, Albert Einstein College of Medicine, 1300 Morris Park Avenue, F312, Bronx, New York 10461, USA

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( Longuet et al . 2013 ). Role of glucagon in food intake and body composition Glucagon has beneficial effects on food intake, body fat mass, and energy expenditure ( Habegger et al . 2010 , Heppner et al . 2010 ). In addition, glucagon has a satiety

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-14-0614
Volume/Issue:
Volume 224: Issue 3
Free access
Christine M A Martin SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, BT52 1SA, UK

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Vadivel Parthsarathy SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, BT52 1SA, UK

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Varun Pathak SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, BT52 1SA, UK

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Victor A Gault SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, BT52 1SA, UK

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Peter R Flatt SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, BT52 1SA, UK

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Nigel Irwin SAAD Centre for Pharmacy and Diabetes, University of Ulster, Coleraine, Northern Ireland, BT52 1SA, UK

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.001 compared with glucose alone. Satiety effects of xenin-25 and related fragment peptides in normal mice None of the peptides examined had any significant effects on feeding behaviour compared with saline-treated controls over the 120 min period ( Fig. 6

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0617
Volume/Issue:
Volume 221: Issue 2
Free access
Raylene A Reimer Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4
Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4

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Gary J Grover Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4
Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4

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Lee Koetzner Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4

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Roland J Gahler Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4

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Michael R Lyon Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4
Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4

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Simon Wood Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4
Faculty of Kinesiology, Department of Biochemistry and Molecular Biology, Product Safety Labs, Department of Physiology and Biophysics, Factors Group of Nutritional Companies, Canadian Centre for Functional Medicine, University of British Columbia, Faculty of Medicine, University of Calgary, 2500 University Drive Northwest, Calgary, Alberta, Canada T2N 1N4

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hyperglycemia, enhance satiety, and improve bowel function depending on the fiber examined ( Weickert & Pfeiffer 2008 ). In general, viscous dietary fibers reduce glycemia to a greater extent than non-viscous fibers ( Chutkan et al . 2012 ). PolyGlycopleX (α- d

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0484
Volume/Issue:
Volume 220: Issue 3
Free access
Gideon Hen Institute of Animal Science, Agricultural Research Organization, Volcani Center, PO Box 6, Bet Dagan 50250, Israel
Department of Chemistry, University of Arizona, Tucson, Arizona 85721, USA

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Sara Yosefi Institute of Animal Science, Agricultural Research Organization, Volcani Center, PO Box 6, Bet Dagan 50250, Israel
Department of Chemistry, University of Arizona, Tucson, Arizona 85721, USA

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Victoria Simchaev Institute of Animal Science, Agricultural Research Organization, Volcani Center, PO Box 6, Bet Dagan 50250, Israel
Department of Chemistry, University of Arizona, Tucson, Arizona 85721, USA

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Dmitry Shinder Institute of Animal Science, Agricultural Research Organization, Volcani Center, PO Box 6, Bet Dagan 50250, Israel
Department of Chemistry, University of Arizona, Tucson, Arizona 85721, USA

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Victor J Hruby Institute of Animal Science, Agricultural Research Organization, Volcani Center, PO Box 6, Bet Dagan 50250, Israel
Department of Chemistry, University of Arizona, Tucson, Arizona 85721, USA

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Miriam Friedman-Einat Institute of Animal Science, Agricultural Research Organization, Volcani Center, PO Box 6, Bet Dagan 50250, Israel
Department of Chemistry, University of Arizona, Tucson, Arizona 85721, USA

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injection, whereas the treated broilers matched their controls some time between 8 and 24 h after injection. A comparison of the satiety effect of the MT-II treatment on broiler and layer chicks is shown in Fig. 2 , where the cumulative food intake of each

Article Type:
Research Article
DOI:
https://doi.org/10.1677/joe.1.06783
Volume/Issue:
Volume 190: Issue 2
Free access