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Dimitri Novitzky and David K C Cooper

Introduction: thyroid hormone and the euthyroid sick syndrome Thyroid hormone production, function, and interaction with other endocrine systems are well understood ( Flood et al . 2013 , Duarte-Guterman et al . 2014 ). Control of the thyroid

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A J Forhead and A L Fowden

Introduction The thyroid hormones, thyroxine (T 4 ) and triiodothyronine (T 3 ), are detectable in the fetal circulation from early in gestation and have important developmental, metabolic, and maturational effects in the fetus in all species

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Noelia Martínez-Sánchez, José M Moreno-Navarrete, Cristina Contreras, Eva Rial-Pensado, Johan Fernø, Rubén Nogueiras, Carlos Diéguez, José-Manuel Fernández-Real and Miguel López

Introduction Thyroid hormones (THs; 3,3′,5,5′ tetraiodothyroxyne or T 4 and 3,3′,5-triiodothyronine or T 3 ) exert important biological actions, not only modulating the development and growth but also regulating metabolism and energy balance

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J Fahrenkrug, B Georg, J Hannibal and H L Jørgensen

thyroid hormones. Studies in rats on the existence of a daily oscillating pattern of thyroid hormones in the circulation have, however, not been quite unequivocal, although most favour a diurnal peak of thyroxin (T4) and triiodothyronine (T3) during the

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Marta Toral, Rosario Jimenez, Sebastián Montoro-Molina, Miguel Romero, Rosemary Wangensteen, Juan Duarte and Félix Vargas

A, CAT-2B, CAT-3 and CAT-4), is the major cationic amino acid transport system and accounts for ~60% of the transport of the intracellular supply of L-arginine for NOS ( Verrey et al. 2004 ). Thyroid hormone excess is associated with a

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Aline Cordeiro, Luana Lopes de Souza, Lorraine Soares Oliveira, Larissa Costa Faustino, Letícia Aragão Santiago, Flavia Fonseca Bloise, Tania Maria Ortiga-Carvalho, Norma Aparecida dos Santos Almeida and Carmen Cabanelas Pazos-Moura

induced by high-fat diet ingestion are attenuated ( Baur et al . 2006 , Feige et al . 2008 , Pfluger et al . 2008 ). However, at this point in time, our knowledge on SIRT1 protein expression regulation is limited. Similar to SIRT1, thyroid hormones

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P C Lisboa, E de Oliveira, A C Manhães, A P Santos-Silva, C R Pinheiro, V Younes-Rapozo, L C Faustino, T M Ortiga-Carvalho and E G Moura

adrenal function and serum glucocorticoid levels with higher levels of corticotropin-releasing hormone (CRH) and adrenocorticotropic hormone (ACTH) in adult offspring whose mothers were nicotine-exposed (Pinheiro et al . 2011). Thyroid hormones (THs), T 4

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Marian Ludgate

In a paper entitled ‘Influence of thyroidectomy on thyroxine metabolism and turnover rate in rats’, Nagao et al . (2011) have investigated thyroid hormone kinetics in the hypothyroid state. In a number of carefully performed studies, which rely

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Andréa Gonçalves Trentin

& Robitaille 2003 , Nedergaard et al. 2003 , Bachoo et al. 2004 ). Astrocytes are mediators of thyroid hormone metabolism in the brain The importance of thyroid hormone for normal brain development is well documented

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J Patel, K Landers, H Li, R H Mortimer and K Richard

development was made very much later ( Cranefield 1962 , Morreale de Escobar et al . 2004 ). Thyroid hormones (thyroxine (T 4 ) and triiodothyronine (T 3 )) are essential for the development and maintenance of normal physiological processes, especially