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Emmely M de Vries Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

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Eric Fliers Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

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Anita Boelen Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

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-2797(97)00139-7 ) Visser WE Friesema EC Visser TJ 2011 Minireview: Thyroid hormone transporters: the knowns and the unknowns . Molecular Endocrinology 25 1 – 14 . ( doi:10.1210/me.2010-0095 ) de Vries EM Kwakkel J Eggels L Kalsbeek A Barrett P

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Review Article
DOI:
https://doi.org/10.1530/JOE-15-0133
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Volume 225: Issue 3
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Juan Bernal Instituto de Investigaciones Biomedicas Alberto Sols, Consejo Superior de Investigaciones Científicas (CSIC) and Universidad Autónoma de Madrid, Madrid, Spain

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Beatriz Morte Center for Biomedical Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, Madrid, Spain

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Diego Diez Immunology Frontier Research Center, Osaka University, Osaka, Japan

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hormones during development. In this paper, we will analyze the development of the human neocortex in the context of thyroid pathophysiology and review recent work on the expression of thyroid hormone transporters, deiodinases, and receptors through

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https://doi.org/10.1530/JOE-22-0189
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Volume 255: Issue 3
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Andréa Gonçalves Trentin Departatmento Biologia Celular, Embriologia e Genética, Centro de Ciências Biológicas, Universidade Federal de Santa Catarina, Campus Universitário, 88040-900, Trindade, Florianópolis, S.C., Brazil

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thyroid hormone diffusion through the plasma membrane has been questioned by the identification of several thyroid hormone transporters ( Hennemann et al. 2001 , Abe et al. 2002 ). Recently, the organic anion-transport polypeptide Oatp14 was reported

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DOI:
https://doi.org/10.1677/joe.1.06680
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Volume 189: Issue 2
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J Patel School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia
School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia

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K Landers School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia

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H Li School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia

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R H Mortimer School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia
School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia
School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia

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K Richard School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia
School of Medicine, Conjoint Endocrine Laboratory, Disciplines of Medicine, The University of Queensland, Herston, 4006 Brisbane, Queensland, Australia

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). They exhibit excessive T 3 -responsive gene activation during development and reduced activation later in life ( Horn & Heuer 2010 ). Thyroid hormone transporters in the brain Over the last decade, the notion of thyroid hormone uptake into cells

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https://doi.org/10.1530/JOE-10-0444
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Volume 209: Issue 1
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A J Forhead Department of Physiology, Department of Biological and Medical Sciences, Development and Neuroscience, University of Cambridge, Physiology Building, Downing Street, Cambridge CB2 3EG, UK
Department of Physiology, Department of Biological and Medical Sciences, Development and Neuroscience, University of Cambridge, Physiology Building, Downing Street, Cambridge CB2 3EG, UK

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A L Fowden Department of Physiology, Department of Biological and Medical Sciences, Development and Neuroscience, University of Cambridge, Physiology Building, Downing Street, Cambridge CB2 3EG, UK

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.83G) Rise in plasma T 3 30 weeks to birth 135 days to birth Birth to 3 weeks postnatally Gene and protein expression of thyroid hormone transporters 7–9 (0.18–0.23G) cerebral cortex Thyroid hormone receptor binding 10–16 (0.25–0.40G) brain, heart

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https://doi.org/10.1530/JOE-14-0025
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Volume 221: Issue 3
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Maria H Warner Clinical Biochemistry, University of Edinburgh, The Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK

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Geoffrey J Beckett Clinical Biochemistry, University of Edinburgh, The Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, UK

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in NTIS; the role of thyroid hormone transporters Although changes in the circulating concentrations of thyroid hormones are commonly discussed in reference to NTIS, tissue thyroid status is governed by intracellular T 3 , particularly that which

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https://doi.org/10.1677/JOE-09-0412
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Volume 205: Issue 1
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Joke Delbaere Laboratory of Comparative Endocrinology, Department of Biology, KU Leuven, Leuven, Belgium

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Pieter Vancamp Laboratory of Comparative Endocrinology, Department of Biology, KU Leuven, Leuven, Belgium

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Stijn L J Van Herck Laboratory of Comparative Endocrinology, Department of Biology, KU Leuven, Leuven, Belgium

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Nele M A Bourgeois Laboratory of Comparative Endocrinology, Department of Biology, KU Leuven, Leuven, Belgium

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Mary J Green Medical Research Council Centre for Developmental Neurobiology, King’s College London, London, UK

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Richard J T Wingate Medical Research Council Centre for Developmental Neurobiology, King’s College London, London, UK

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Veerle M Darras Laboratory of Comparative Endocrinology, Department of Biology, KU Leuven, Leuven, Belgium

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granule cell axons in the developing cerebellum . Neural Development 3 7 . ( doi:10.1186/1749-8104-3-7 ) Bernal J Guadano-Ferraz A Morte B 2015 Thyroid hormone transporters-functions and clinical implications . Nature Reviews

Article Type:
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DOI:
https://doi.org/10.1530/JOE-16-0323
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Volume 232: Issue 2
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S-Y Chan Department of Fetal Medicine, Division of Reproductive & Child Health, University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
Division of Medical Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Department of Internal Medicine, Erasmus University Medical Centre, 3015 GE, Rotterdam, The Netherlands
School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4 LP, UK

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J A Franklyn Department of Fetal Medicine, Division of Reproductive & Child Health, University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
Division of Medical Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Department of Internal Medicine, Erasmus University Medical Centre, 3015 GE, Rotterdam, The Netherlands
School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4 LP, UK

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H N Pemberton Department of Fetal Medicine, Division of Reproductive & Child Health, University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
Division of Medical Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Department of Internal Medicine, Erasmus University Medical Centre, 3015 GE, Rotterdam, The Netherlands
School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4 LP, UK

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J N Bulmer Department of Fetal Medicine, Division of Reproductive & Child Health, University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
Division of Medical Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Department of Internal Medicine, Erasmus University Medical Centre, 3015 GE, Rotterdam, The Netherlands
School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4 LP, UK

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T J Visser Department of Fetal Medicine, Division of Reproductive & Child Health, University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
Division of Medical Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Department of Internal Medicine, Erasmus University Medical Centre, 3015 GE, Rotterdam, The Netherlands
School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4 LP, UK

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C J McCabe Department of Fetal Medicine, Division of Reproductive & Child Health, University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
Division of Medical Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Department of Internal Medicine, Erasmus University Medical Centre, 3015 GE, Rotterdam, The Netherlands
School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4 LP, UK

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M D Kilby Department of Fetal Medicine, Division of Reproductive & Child Health, University of Birmingham, Edgbaston, Birmingham B15 2TG, UK
Division of Medical Sciences, Medical School, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
Department of Internal Medicine, Erasmus University Medical Centre, 3015 GE, Rotterdam, The Netherlands
School of Clinical and Laboratory Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 4 LP, UK

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. References Abe T , Suzuki T, Unno M, Tokui T & Ito S 2002 Thyroid hormone transporters: recent advances. Trends in Endocrinology and Metabolism 13 215 –220. Bacon BJ , Gilbert RD & Longo LD 1986

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DOI:
https://doi.org/10.1677/joe.1.06582
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Volume 189: Issue 3
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Shiao Y Chan School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Laura A Hancox School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Azucena Martín-Santos School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Laurence S Loubière School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Merlin N M Walter School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Ana-Maria González School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Phillip M Cox School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Ann Logan School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Christopher J McCabe School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Jayne A Franklyn School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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Mark D Kilby School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
School of Clinical and Experimental Medicine, Department of Pathology, Fetal Medicine Centre, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

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as a specific thyroid hormone transporter . Journal of Biological Chemistry 278 40128 – 40135 . ( doi:10.1074/jbc.M300909200 ) Friesema EC Grueters A Biebermann H Krude H von Moers A Reeser M Barrett TG Mancilla EE Svensson J Kester MH 2004

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https://doi.org/10.1530/JOE-13-0400
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Volume 220: Issue 2
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N Shimada Department of Biology, Faculty of Science, Shizuoka University, 836 Ohya, Shizuoka 422-8529, Japan

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K Yamauchi Department of Biology, Faculty of Science, Shizuoka University, 836 Ohya, Shizuoka 422-8529, Japan

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& Ito S 2002 Thyroid hormone transporters: recent advances. Trends in Endocrinology and Metabolism 13 215 –220. Blondeau J-P, Osty J & Francon J 1988 Characterization of the thyroid hormone transport system of isolated

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DOI:
https://doi.org/10.1677/joe.1.05893
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Volume 183: Issue 3
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