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Tanasescu R Coculescu M Mihai R 1998 Vasopressin neurotransmission and the control of circadian rhythms in the suprachiasmatic nucleus . Progress in Brain Research 119 351 – 364 . Irwin RP Allen CN 2009 GABAergic signaling
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-regulated extracellular matrix glycoprotein ( Alvarez-Dolado et al. 1999 ), reelin (RELN), a stop signal for neuron migration ( Jossin 2020 ). The whole process is known as ‘inside-out radial migration’, by which the neurons are sequentially positioned in layers
Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
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Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
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Diabetes and Obesity Research Laboratory, Department of Endocrinology and Nutrition, Centro de Investigación Biomédica en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain
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food intake in humans . Journal of Clinical Endocrinology and Metabolism 86 5992 . ( doi:10.1210/jc.86.12.5992 ) Wu Q Palmiter RD 2011 GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism . European Journal of
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affect GnRH neurons as reproductive gating. In addition, increasing evidence suggests that GABAergic neurons and populations of PACAP neurons are important first-order targets of peripheral metabolic signals (a typical example is leptin) that mediate the
Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, Salamanca, Spain
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), CSIC-University of Salamanca, Salamanca, Spain
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Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, Salamanca, Spain
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), CSIC-University of Salamanca, Salamanca, Spain
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Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, Salamanca, Spain
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Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, University of Santiago de Compostela, Santiago de Compostela, Spain
Centro de Investigación Biomédica en Red de Cáncer sobre la Fisiopatología de la Obesidad y Nutrición (CIBEROBN), University of Santiago de Compostela, Santiago de Compostela, Spain
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Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, Salamanca, Spain
Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), CSIC-University of Salamanca, Salamanca, Spain
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Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, Salamanca, Spain
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Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, Salamanca, Spain
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Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, Salamanca, Spain
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Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, University of Santiago de Compostela, Santiago de Compostela, Spain
Centro de Investigación Biomédica en Red de Cáncer sobre la Fisiopatología de la Obesidad y Nutrición (CIBEROBN), University of Santiago de Compostela, Santiago de Compostela, Spain
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Centro de Investigación en Medicina Molecular e Enfermidades Crónicas, University of Santiago de Compostela, Santiago de Compostela, Spain
Centro de Investigación Biomédica en Red de Cáncer sobre la Fisiopatología de la Obesidad y Nutrición (CIBEROBN), University of Santiago de Compostela, Santiago de Compostela, Spain
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Instituto de Biología Molecular y Celular del Cáncer, CSIC-University of Salamanca, Salamanca, Spain
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the stimulation of the RVLM ( Saper 2002 , Guyenet 2006 , Grill & Hayes 2012 ). The most usual mechanism to achieve this effect is the NTS-mediated elimination of the tonic GABAergic signals emitted by the CVLM ( Guyenet 2006 , Grill & Hayes 2012
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neurotransmitter syntheses and signaling ( Khrimian et al. 2017 b , Kosmidis et al. 2018 ), thus playing a crucial role in brain development, cognitive function and motor coordination ( Khrimian et al. 2017 a , b , Guo et al. 2018 , Glatigny et al
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Department of Anatomy, Semmelweis University, Budapest, Hungary
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Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
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receptors ( Crhr1 and Crhr2 ) and CRH-binding protein ( Crhbp ). Note that some cells in clusters #14 (GABA) and #44 (glutamate) can express at least one receptor and binding protein for CRH signaling. Red and green colors identify respective GABAergic and
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timekeeping properties and in their acute responses to environmental signals. In addition, while SCN neurons are GABAergic in nature, they are also neurochemically diverse, with subsets of cells expressing a wide variety of peptide co-transmitters such as
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middle-income countries . Lancet Diabetes & Endocrinology 8 1 – 10 . ( https://doi.org/10.1016/S2213-8587(19)30082-8 ) Legat L Smolders I Dupont AG 2018 GABAergic signaling mediates central cardiovascular angiotensin II type 2 receptor
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. 2022 ). Hypothalamic insulin and leptin resistance are driven in part by increased levels of protein tyrosine phosphatase 1B (PTP1B) and suppressor of cytokine signaling 3 (SOCS3), negative regulators of insulin and leptin signaling pathways ( Salmeen