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In vivo blockade of ovarian sympathetic activity by Neosaxitoxin prevents polycystic ovary in rats

Miguel del Campo, Néstor Lagos, and Hernán Lara

ovary by local chronic administration of Neosaxitoxin (NeoSTX), a toxin that specifically blocks the voltage-dependent Na+ channels with a high affinity and long half-life ( Llewellyn 2006 , Alonso et al . 2016 ). NeoSTX was administered using a mini