Filter

Refine by date

—

Refine by collections

Refine by access

  • Print
  • Save

Search Results

You are looking at 1 - 10 of 949 items for :

  • Refine by access: All content x
Clear All
Tomoaki Hayakawa Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

Search for other papers by Tomoaki Hayakawa in
Google Scholar
PubMed Close
,
Tomomi Minemura Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

Search for other papers by Tomomi Minemura in
Google Scholar
PubMed Close
,
Toshiharu Onodera Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

Search for other papers by Toshiharu Onodera in
Google Scholar
PubMed Close
,
Jihoon Shin Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
Department of Diabetes Care Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

Search for other papers by Jihoon Shin in
Google Scholar
PubMed Close
,
Yosuke Okuno Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

Search for other papers by Yosuke Okuno in
Google Scholar
PubMed Close
,
Atsunori Fukuhara Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
Department of Adipose Management, Osaka University Graduate School of Medicine, Osaka, Japan

Search for other papers by Atsunori Fukuhara in
Google Scholar
PubMed Close
,
Michio Otsuki Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

Search for other papers by Michio Otsuki in
Google Scholar
PubMed Close
, and
Iichiro Shimomura Department of Metabolic Medicine, Osaka University Graduate School of Medicine, Osaka, Japan

Search for other papers by Iichiro Shimomura in
Google Scholar
PubMed Close

syndrome and also in obese individuals ( Hirata et al . 2009 , 2012 ; Urbanet et al . 2015 ). Treatment with eplerenone, a specific MR blocker, partially reverses the obesity-associated dysfunction of adipocytes and insulin resistance in mice ( Guo et

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0026
Volume/Issue:
Volume 239: Issue 1
Free access
Olena A Fedorenko School of Life Sciences, University of Nottingham, Nottingham, UK

Search for other papers by Olena A Fedorenko in
Google Scholar
PubMed Close
,
Pawitra Pulbutr Faculty of Pharmacy, Mahasarakham University, Mahasarakham, Thailand

Search for other papers by Pawitra Pulbutr in
Google Scholar
PubMed Close
,
Elin Banke Department of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Göteborg, Sweden

Search for other papers by Elin Banke in
Google Scholar
PubMed Close
,
Nneoma E Akaniro-Ejim School of Life Sciences, University of Nottingham, Nottingham, UK

Search for other papers by Nneoma E Akaniro-Ejim in
Google Scholar
PubMed Close
,
Donna C Bentley School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, UK

Search for other papers by Donna C Bentley in
Google Scholar
PubMed Close
,
Charlotta S Olofsson Department of Physiology/Metabolic Physiology, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at University of Gothenburg, Göteborg, Sweden

Search for other papers by Charlotta S Olofsson in
Google Scholar
PubMed Close
,
Sue Chan School of Life Sciences, University of Nottingham, Nottingham, UK

Search for other papers by Sue Chan in
Google Scholar
PubMed Close
, and
Paul A Smith School of Life Sciences, University of Nottingham, Nottingham, UK

Search for other papers by Paul A Smith in
Google Scholar
PubMed Close

Introduction White fat adipocytes (WFA) are the major energy depot of the body, storing and releasing energy in response to the calorific demands of the body during periods of excess and need respectively ( Arner et al. 2011 ). It is widely

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-19-0493
Volume/Issue:
Volume 244: Issue 2
Restricted access
Rafaela Fadoni Alponti Laboratory of Pharmacology, Department of Physiology, Unit of Translational Endocrine Physiology and Pharmacology, Instituto Butantan, Avenida Vital Brasil, 1500, CEP05503‐900 Sao Paulo, Brazil
Laboratory of Pharmacology, Department of Physiology, Unit of Translational Endocrine Physiology and Pharmacology, Instituto Butantan, Avenida Vital Brasil, 1500, CEP05503‐900 Sao Paulo, Brazil

Search for other papers by Rafaela Fadoni Alponti in
Google Scholar
PubMed Close
,
Patricia Lucio Alves Laboratory of Pharmacology, Department of Physiology, Unit of Translational Endocrine Physiology and Pharmacology, Instituto Butantan, Avenida Vital Brasil, 1500, CEP05503‐900 Sao Paulo, Brazil

Search for other papers by Patricia Lucio Alves in
Google Scholar
PubMed Close
, and
Paulo Flavio Silveira Laboratory of Pharmacology, Department of Physiology, Unit of Translational Endocrine Physiology and Pharmacology, Instituto Butantan, Avenida Vital Brasil, 1500, CEP05503‐900 Sao Paulo, Brazil

Search for other papers by Paulo Flavio Silveira in
Google Scholar
PubMed Close

(ANG) IV receptor ( Albiston et al . 2010 ), has an important interaction with subcellular distribution of GLUT4 in adipocytes ( Jordens et al . 2010 ). IRAP is well-recognized as a companion of glucose transporter GLUT4 and a key regulator of the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0266
Volume/Issue:
Volume 228: Issue 2
Free access
Gulizar Issa Ameen Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

Search for other papers by Gulizar Issa Ameen in
Google Scholar
PubMed Close
and
Silvia Mora Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK

Search for other papers by Silvia Mora in
Google Scholar
PubMed Close

Introduction Casitas b-lymphoma (Cbl) is a proximal insulin receptor adaptor protein identified as necessary for insulin-mediated activation of glucose transport in adipocytes ( Baumann et al . 2000 , Chiang et al . 2001 , Chang et al

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-17-0359
Volume/Issue:
Volume 236: Issue 1
Open access
Miriam Thomalla Department of Internal Medicine III, Giessen University Hospital, Giessen, Germany

Search for other papers by Miriam Thomalla in
Google Scholar
PubMed Close
,
Andreas Schmid Department of Internal Medicine III, Giessen University Hospital, Giessen, Germany

Search for other papers by Andreas Schmid in
Google Scholar
PubMed Close
,
Elena Neumann Department of Rheumatology and Clinical Immunology, University of Giessen and Kerckhoff Clinic, Bad Nauheim, Germany

Search for other papers by Elena Neumann in
Google Scholar
PubMed Close
,
Petra Ina Pfefferle Comprehensive Biomaterial Bank Marburg (CBBMR), Philipps-University of Marburg, Marburg, Germany

Search for other papers by Petra Ina Pfefferle in
Google Scholar
PubMed Close
,
Ulf Müller-Ladner Department of Rheumatology and Clinical Immunology, University of Giessen and Kerckhoff Clinic, Bad Nauheim, Germany

Search for other papers by Ulf Müller-Ladner in
Google Scholar
PubMed Close
,
Andreas Schäffler Department of Internal Medicine III, Giessen University Hospital, Giessen, Germany

Search for other papers by Andreas Schäffler in
Google Scholar
PubMed Close
, and
Thomas Karrasch Department of Internal Medicine III, Giessen University Hospital, Giessen, Germany

Search for other papers by Thomas Karrasch in
Google Scholar
PubMed Close

( Schaffler et al . 2005 , 2006 , 2007 ). Obesity is associated with a significant pro-inflammatory transformation of the complex cellular environment of adipose tissue (encompassing adipocytes, pre-adipocytes, fibroblasts, monocytes, macrophages

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0326
Volume/Issue:
Volume 240: Issue 2
Free access
M Skrzypski Department of Animal Physiology and Biochemistry, Poznań University of Life Sciences, Poznań

Search for other papers by M Skrzypski in
Google Scholar
PubMed Close
,
M Billert Department of Animal Physiology and Biochemistry, Poznań University of Life Sciences, Poznań

Search for other papers by M Billert in
Google Scholar
PubMed Close
,
K W Nowak Department of Animal Physiology and Biochemistry, Poznań University of Life Sciences, Poznań

Search for other papers by K W Nowak in
Google Scholar
PubMed Close
, and
M Z Strowski Department of Hepatology and Gastroenterology & The Interdisciplinary Centre of Metabolism: Endocrinology, Diabetes and Metabolism, Charité-University Medicine Berlin, Berlin, Germany
Park-Klinik Weissensee, Internal Medicine – Gastroenterology, Berlin, Germany

Search for other papers by M Z Strowski in
Google Scholar
PubMed Close

glucose and lipid metabolism. Orexin in adipose tissue Expression of orexin and orexin receptors in white adipose tissue Despite some inconsistencies, it appears that both OXR isoforms are present in adipocytes. While OXR1 and OXR2 were

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-18-0122
Volume/Issue:
Volume 238: Issue 2
Free access
Noriko Tagawa Department of Medical Biochemistry, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan

Search for other papers by Noriko Tagawa in
Google Scholar
PubMed Close
,
Sayaka Kubota Department of Medical Biochemistry, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan

Search for other papers by Sayaka Kubota in
Google Scholar
PubMed Close
,
Ikuo Kato Department of Medical Biochemistry, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan

Search for other papers by Ikuo Kato in
Google Scholar
PubMed Close
, and
Yoshiharu Kobayashi Department of Medical Biochemistry, Kobe Pharmaceutical University, 4-19-1 Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan

Search for other papers by Yoshiharu Kobayashi in
Google Scholar
PubMed Close

. Recently, evidence has been accumulated that intracellular glucocorticoid amplification in adipocytes by 11β-HSD1 contributes to central obesity and, consequently, promotes metabolic diseases in experimental animals ( Masuzaki et al . 2001 ) and humans

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0066
Volume/Issue:
Volume 218: Issue 3
Free access
A Tsuchiya Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan

Search for other papers by A Tsuchiya in
Google Scholar
PubMed Close
,
T Kanno Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan

Search for other papers by T Kanno in
Google Scholar
PubMed Close
, and
T Nishizaki Division of Bioinformation, Department of Physiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan

Search for other papers by T Nishizaki in
Google Scholar
PubMed Close

glucose uptake into cells, and assayed Akt1/2 activity in 3T3-L1 adipocytes expressing myc-tagged GLUT4 (3T3-L1-GLUT4myc adipocytes) and under cell-free conditions. We show here that insulin stimulates GLUT4 translocation to the cell surface and increases

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0172
Volume/Issue:
Volume 220: Issue 1
Open access
Junlan Zhou
Search for other papers by Junlan Zhou in
Google Scholar
PubMed Close
,
Min Cheng Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by Min Cheng in
Google Scholar
PubMed Close
,
Chan Boriboun
Search for other papers by Chan Boriboun in
Google Scholar
PubMed Close
,
Mariam M Ardehali
Search for other papers by Mariam M Ardehali in
Google Scholar
PubMed Close
,
Changfei Jiang Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by Changfei Jiang in
Google Scholar
PubMed Close
,
Qinghua Liu Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by Qinghua Liu in
Google Scholar
PubMed Close
,
Shuling Han
Search for other papers by Shuling Han in
Google Scholar
PubMed Close
,
David A Goukassian Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by David A Goukassian in
Google Scholar
PubMed Close
,
Yao-Liang Tang Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by Yao-Liang Tang in
Google Scholar
PubMed Close
,
Ting C Zhao Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by Ting C Zhao in
Google Scholar
PubMed Close
,
Ming Zhao
Search for other papers by Ming Zhao in
Google Scholar
PubMed Close
,
Lu Cai Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by Lu Cai in
Google Scholar
PubMed Close
,
Stéphane Richard Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by Stéphane Richard in
Google Scholar
PubMed Close
,
Raj Kishore Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

Search for other papers by Raj Kishore in
Google Scholar
PubMed Close
, and
Gangjian Qin
Search for other papers by Gangjian Qin in
Google Scholar
PubMed Close

resistance, type 2 diabetes, and cardiovascular disease ( Bornfeldt & Tabas 2011 ). In the body, white adipose tissue (WAT) is a major lipid depot that contains unilocular white adipocytes for storing vast amounts of nutrients as lipids. Brown adipose tissue

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-14-0727
Volume/Issue:
Volume 225: Issue 3
Free access
Xiwen Xiong Department of Forensic Medicine, Xinxiang Medical University, Xinxiang, Henan, China

Search for other papers by Xiwen Xiong in
Google Scholar
PubMed Close
,
Cuicui Zhang School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, China

Search for other papers by Cuicui Zhang in
Google Scholar
PubMed Close
,
Yang Zhang Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, USA

Search for other papers by Yang Zhang in
Google Scholar
PubMed Close
,
Rui Fan School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, China

Search for other papers by Rui Fan in
Google Scholar
PubMed Close
,
Xinlai Qian School of Basic Medical Sciences, Xinxiang Medical University, Xinxiang, Henan, China

Search for other papers by Xinlai Qian in
Google Scholar
PubMed Close
, and
X Charlie Dong Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, USA

Search for other papers by X Charlie Dong in
Google Scholar
PubMed Close

). However, the role of SIRT6 in adipose tissue is not well understood. Conditional gene knockout with the use of cell type-specific Cre lines is a powerful technique to ablate a specific gene in a target cell type, such as the adipocyte ( Wang 2009 ). As a

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-17-0033
Volume/Issue:
Volume 233: Issue 3
Free access