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Alia H Sukkar Section for Nutrition Research, Department of Medicine, Imperial College London, London, UK

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Aaron M Lett Section for Nutrition Research, Department of Medicine, Imperial College London, London, UK

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Gary Frost Section for Nutrition Research, Department of Medicine, Imperial College London, London, UK

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Edward S Chambers Section for Nutrition Research, Department of Medicine, Imperial College London, London, UK

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protect against HFD induced obesity by promoting beiging of WAT, which would increase energy expenditure and fatty acid oxidation. Mice fed an HFD supplemented with SCFAs had higher expression of genes related to mitochondrial biogenesis, including Ppargc

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-19-0098
Volume/Issue:
Volume 242: Issue 2
Free access
Nigel Turner Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia
Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia

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Gregory J Cooney Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia
Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia

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Edward W Kraegen Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia
Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia

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Clinton R Bruce Department of Pharmacology, School of Medical Sciences, Diabetes and Obesity Division, St Vincent's Clinical School, Department of Physiology, University of New South Wales, Sydney, New South Wales, Australia

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. ( doi:10.1073/pnas.0902380106 ) Hoehn KL Turner N Swarbrick MM Wilks D Preston E Phua Y Joshi H Furler SM Larance M Hegarty BD 2010 Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-13-0397
Volume/Issue:
Volume 220: Issue 2
Free access
Hannah M Eggink Department of Endocrinology and Metabolism, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

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Lauren L Tambyrajah Division of Endocrinology, Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands

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Rosa van den Berg Division of Endocrinology, Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands

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Isabel M Mol Division of Endocrinology, Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands

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Jose K van den Heuvel Division of Endocrinology, Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands

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Martijn Koehorst Department of Pediatrics and Laboratory Medicine, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands

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Albert K Groen Department of Pediatrics and Laboratory Medicine, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
Department of Vascular Medicine, Amsterdam Diabetes Centre, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands

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Anita Boelen Department of Endocrinology and Metabolism, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands

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Andries Kalsbeek Department of Endocrinology and Metabolism, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Hypothalamic Integration Mechanisms, Netherlands Institute for Neuroscience, Amsterdam, The Netherlands

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Johannes A Romijn Department of Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands

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Patrick C N Rensen Division of Endocrinology, Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands

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Sander Kooijman Division of Endocrinology, Department of Medicine, Leiden University Medical Centre, Leiden, The Netherlands
Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Centre, Leiden, The Netherlands

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Maarten R Soeters Department of Endocrinology and Metabolism, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands

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control group in mRNA expression of genes involved in lipid oxidation and the previously reported BA-induced TGR5-D2-UCP1 pathway ( Fig. 6E ). Together these data seem to suggest that tLCA regulates energy expenditure through central bile acid signaling by

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-17-0503
Volume/Issue:
Volume 236: Issue 2
Free access
Amanda E Brandon Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia
Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia

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Ella Stuart Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia

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Simon J Leslie Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia

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Kyle L Hoehn Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia

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David E James Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia

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Edward W Kraegen Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia
Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia

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Nigel Turner Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia

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Gregory J Cooney Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia
Diabetes and Metabolism Division, St Vincent's Clinical School, School of Medical Sciences, School of Biotechnology and Biomolecular Sciences, School of Molecular Bioscience and Sydney Medical School, Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia

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Acc2 knockout mice reported a lean phenotype with improved insulin action due to increased whole-body and muscle fatty acid oxidation (FAO) and higher energy expenditure ( Abu-Elheiga et al . 2001 , Abu-Elheiga et al . 2003 , Choi et al . 2007

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-15-0444
Volume/Issue:
Volume 228: Issue 3
Free access
Kishor Devalaraja-Narashimha Department of Cellular and Integrative Physiology, Section of Nephrology, Department of Internal Medicine, University of Nebraska Medical Center, 985850 Nebraska Medical Center, Omaha, Nebraska 68198-5850, USA

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Babu J Padanilam Department of Cellular and Integrative Physiology, Section of Nephrology, Department of Internal Medicine, University of Nebraska Medical Center, 985850 Nebraska Medical Center, Omaha, Nebraska 68198-5850, USA
Department of Cellular and Integrative Physiology, Section of Nephrology, Department of Internal Medicine, University of Nebraska Medical Center, 985850 Nebraska Medical Center, Omaha, Nebraska 68198-5850, USA

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mice ( Fig. 5 A). The RQ of 0.76 in Parp -KO mice indicates that these mice used fatty acids as the main energy source, while a RQ of 0.82 in WT mice indicated the use of both carbohydrates and fat as their energy source suggesting Parp -KO mice

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0402
Volume/Issue:
Volume 205: Issue 3
Free access
David A Baltzegar Department of Biological Sciences, North Carolina State University, Campus Box 7617, Raleigh, North Carolina 27695-7617, USA

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Benjamin J Reading Department of Biological Sciences, North Carolina State University, Campus Box 7617, Raleigh, North Carolina 27695-7617, USA

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Jonathon D Douros Department of Biological Sciences, North Carolina State University, Campus Box 7617, Raleigh, North Carolina 27695-7617, USA

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Russell J Borski Department of Biological Sciences, North Carolina State University, Campus Box 7617, Raleigh, North Carolina 27695-7617, USA

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total metabolic energy demand ( Morgan et al . 1997 , Bœuf & Payan 2001 ). The primary site of ion exchange is the gill ( Evans et al . 2005 ), which has a low capacity for the oxidation of fatty acids or ketones ( Segner et al . 1997 , Crockett et

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0292
Volume/Issue:
Volume 220: Issue 1
Free access
Samira Fargali Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Thomas Scherer Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Andrew C Shin Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Masato Sadahiro Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Christoph Buettner Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA
Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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Stephen R Salton Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA
Departments of, Neuroscience, Medicine, Geriatrics, Box 1065, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, New York 10029, USA

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energy expenditure ( Choi et al . 2007 ), or no net effect on energy balance or adiposity ( Hoehn et al . 2010 ), depending on the line analyzed. The latter study ( Hoehn et al . 2010 ) suggests that chronically increased fatty acid oxidation

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0172
Volume/Issue:
Volume 215: Issue 2
Free access
Junlan Zhou
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Min Cheng Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Chan Boriboun
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Mariam M Ardehali
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Changfei Jiang Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Qinghua Liu Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Shuling Han
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David A Goukassian Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Yao-Liang Tang Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Ting C Zhao Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Ming Zhao
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Lu Cai Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Stéphane Richard Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Raj Kishore Department of Medicine–Cardiology, Department of Cardiology, Department of Biochemistry, Institute for Medical Biology and Hubei Provincial Key Laboratory for Protection and Application of Special Plants in Wuling Area of China, GeneSys Research Institute, Department of Medicine, Department of Surgery, Kosair Children Hospital Research Institute, Lady Davis Institute for Medical Research, Center for Translational Medicine, Feinberg Cardiovascular Research Institute, Northwestern University Feinberg School of Medicine, 303 E Chicago Avenue, Tarry 14‐721, Chicago, Illinois 60611, USA

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Gangjian Qin
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Introduction Obesity, which is characterized by abnormal or excessive fat accumulation resulting from energy intake exceeding expenditure, has become a global epidemic and is associated with an array of medical conditions, including insulin

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-14-0727
Volume/Issue:
Volume 225: Issue 3
Free access
Kristen R Lednovich Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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Sophie Gough Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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Medha Priyadarshini Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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Nupur Pandya Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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Chioma Nnyamah Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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Kai Xu Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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Barton Wicksteed Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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Sidharth Mishra USF Center for Microbiome Research, University of South Florida Morsani College of Medicine, Tampa, Florida, USA

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Shalini Jain USF Center for Microbiome Research, University of South Florida Morsani College of Medicine, Tampa, Florida, USA

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Joseph L Zapater Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA
Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois, USA

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Jose Cordoba-Chacon Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA

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Hariom Yadav USF Center for Microbiome Research, University of South Florida Morsani College of Medicine, Tampa, Florida, USA

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Brian T Layden Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA
Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois, USA

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-body glucose homeostasis ( Fuller et al. 2015 , Priyadarshini et al. 2015 , Villa et al. 2016 ). Within the adipose tissue, FFA2 has been reported to inhibit insulin-mediated fat accumulation while enhancing energy expenditure and systemic insulin

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-23-0184
Volume/Issue:
Volume 260: Issue 2
Open access
Sabina Paglialunga Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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Patrick Schrauwen Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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Christian Roy Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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Esther Moonen-Kornips Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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Huiling Lu Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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Matthijs K C Hesselink Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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Yves Deshaies Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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Denis Richard Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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Katherine Cianflone Department of Biochemistry, McGill University, Montreal, Canada H3G 1V6
Centre de Recherche de l’Hôpital Laval, Université Laval, Y2186, 2725 Chemin Ste-Foy, Québec, Canada G1V 4G5
Department of Human Biology, Nutrition and Toxicology Research Institute Maastricht,
Movement Sciences, Maastricht University, Maastricht, 6200 The Netherlands

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; other indicators of energy expenditure such as physical activity and heat production, as previously demonstrated in ASP-deficient C3KO mice ( Xia et al. 2002 , 2004 ), were not determined. Nonetheless, the compensatory increase in fatty acid

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-07-0205
Volume/Issue:
Volume 194: Issue 2
Free access