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Tianru Jin

intestinal cell lines ( Jin & Drucker 1995 ). *In pancreatic α-cells but not intestinal L cell, insulin represses gcg expression via the G3 element. (B) DNA sequence of the first 300 bp 5′ flanking region of the rat gcg gene. G1 and four enhancer elements are

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Nancy H Nabilsi, Russell R Broaddus, Adrienne S McCampbell, Karen H Lu, Henry T Lynch, Lee-may Chen and David S Loose

gene expression is distinct from the other IAPs. Survivin is highly expressed during embryonic and fetal development and is overexpressed in virtually all tumor types ( Ambrosini et al . 1997 , Li & Altieri 1999 , O'Driscoll et al . 2003 ) including

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Wenxia He, Xiangyan Dai, Xiaowen Chen, Jiangyan He and Zhan Yin

expression profiling studies have been carried out using different organs or tissues, but very few studies have addressed questions on the developmental changes in pituitary gene expression due to maturation and somatic growth processing in zebrafish

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Shanqi Fu, Miho Kuwahara, Yoko Uchida, Sei Kondo, Daichi Hayashi, Yuji Shimomura, Asami Takagaki, Takashi Nishida, Yusuke Maruyama, Mika Ikegame, Atsuhiko Hattori, Satoshi Kubota and Takako Hattori

rhythm that persisted for several months in both articular and growth plate cartilage ( Okubo et al. 2013 ). Recently, several studies have demonstrated the rhythmic expression of clock genes in cartilage, indicating that, similar to the central SCN

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Yi Zhao, Tao Liu, Nina Zhang, Fenghua Yi, Qinghua Wang, Ivan George Fantus and Tianru Jin

expression of both insulin and somatostatin genes ( Leonard et al. 1993 , Ohlsson et al. 1993 , Miller et al. 1994 , Lu et al. 1996 ). Pax-6 is probably involved in regulating the expression of genes that encode insulin, glucagon and somatostatin

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K Horiguchi, S Yagi, K Ono, Y Nishiura, M Tanaka, M Ishida and T Harigaya

, Tokyo, Japan) by monitoring absorbance at 260 nm. We assessed PRL gene expression in the tissues by RT-PCR. We synthesized mouse PRL cDNA in 20 μl buffer containing 50 mM Tris–HCl (pH 8.3), 40 mM KCl, 6 mM MgCl 2 , 1 mM DTT, 200 U/μl RNase inhibitor, 200

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K M Jeckel, A C Boyarko, G J Bouma, Q A Winger and R V Anthony

, chorionic somatomammotropin (CSH, a.k.a. placental lactogen) has long been hypothesized to impact metabolism in both the mother and fetus ( Handwerger 1991 , Handwerger & Freemark 2000 ). CSH is a member of the growth hormone/prolactin gene family that is

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Cesidio Giuliani, Ines Bucci, Valeria Montani, Dinah S Singer, Fabrizio Monaco, Leonard D Kohn and Giorgio Napolitano

. 1999 ). Down-regulation or the absence of MHC class-I gene expression is also considered a hallmark of tissue immune privilege ( Ito et al . 2004 , 2008 ). The involvement of aberrant MHC class-II gene expression in the development of autoimmune

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Guoyue Yuan, Xia Chen, Qinyun Ma, Jie Qiao, Rongying Li, Xuesong Li, Shengxian Li, Jinfeng Tang, Libin Zhou, Huaidong Song and Mingdao Chen

level is a cause or an effect of insulin resistance and decreased adiponectin. In the current study, we therefore examined the effect of CRP on adiponectin gene expression and secretion in 3T3-L1 adipocytes in vitro . We demonstrated that CRP

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Bohan Wang, I Stuart Wood and Paul Trayhurn

, Trayhurn & Beattie 2001 ). Leptin is a hypoxia-sensitive gene; its expression being stimulated in adipocytes by low O 2 tension ( Grosfeld et al . 2002 b , Lolmède et al . 2003 , Polotsky et al . 2003 , Hausman & Richardson 2004 ), through