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Daniela Leite de Oliveira Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Camila Hirotsu Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Sergio Tufik Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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Monica Levy Andersen Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil

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2 ) contributes to inflammatory pain ( Kawabata 2011 ). Another important component of pain mechanism is the immune system. Because of injury, inflammation of the damaged tissue may cause hyperalgesia. Activation of macrophages in the damaged

Article Type:
Review Article
DOI:
https://doi.org/10.1530/JOE-16-0514
Volume/Issue:
Volume 234: Issue 1
Free access
Jing Li Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Pan-Pan Zhao Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Ting Hao Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Dan Wang Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Yu Wang Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Yang-Zi Zhu Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China

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Yu-Qing Wu Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China
Department of Anesthetic Pharmacology, Xuzhou Medical University, Xuzhou, China

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Cheng-Hua Zhou Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, China
Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, Xuzhou Medical University, Xuzhou, China

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( Jarry et al . 2010 ) and our preliminary experiments. The animals in normal, sham and CCI groups received the same volume of 1% DMSO. Behavioral analysis Behavioral measurements were included of mechanical allodynia and thermal hyperalgesia

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-16-0255
Volume/Issue:
Volume 232: Issue 2
Free access
Donato Calabrese
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Silvia Giatti
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Simone Romano
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Carla Porretta-Serapiglia Section of Biomedicine and Endocrinology, Neuromuscular Disease Unit, Department of Pharmacy and Center of Excellence for Biomedical Research, Instituto Cajal, Department of Pharmacological and Biomolecular Sciences, Center of Excellence on Neurodegenerative Diseases, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy

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Roberto Bianchi Section of Biomedicine and Endocrinology, Neuromuscular Disease Unit, Department of Pharmacy and Center of Excellence for Biomedical Research, Instituto Cajal, Department of Pharmacological and Biomolecular Sciences, Center of Excellence on Neurodegenerative Diseases, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy

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Marco Milanese Section of Biomedicine and Endocrinology, Neuromuscular Disease Unit, Department of Pharmacy and Center of Excellence for Biomedical Research, Instituto Cajal, Department of Pharmacological and Biomolecular Sciences, Center of Excellence on Neurodegenerative Diseases, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy

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Giambattista Bonanno Section of Biomedicine and Endocrinology, Neuromuscular Disease Unit, Department of Pharmacy and Center of Excellence for Biomedical Research, Instituto Cajal, Department of Pharmacological and Biomolecular Sciences, Center of Excellence on Neurodegenerative Diseases, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy

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Donatella Caruso
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Barbara Viviani
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Fabrizio Gardoni
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Luis Miguel Garcia-Segura Section of Biomedicine and Endocrinology, Neuromuscular Disease Unit, Department of Pharmacy and Center of Excellence for Biomedical Research, Instituto Cajal, Department of Pharmacological and Biomolecular Sciences, Center of Excellence on Neurodegenerative Diseases, Università degli Studi di Milano, Via Balzaretti 9, 20133 Milano, Italy

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Roberto Cosimo Melcangi
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polysynaptic EPSCs in the dorsal horn are significantly higher in diabetic rats than in controls ( Li et al . 2010 ). Moreover, higher glutamatergic excitation is also supported by pharmacologic studies showing that in diabetic animals hyperalgesia and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-13-0541
Volume/Issue:
Volume 221: Issue 1
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Wolfgang Liedtke Center for Translational Neuroscience, Duke University, Durham, North Carolina 27710, USA

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transduction of osmotic and mechanical stimuli involving TRPV1. Genetically engineered trpv 1 −/− mice, which have previously been shown to lack thermal hyperalgesia following inflammation ( Caterina et al. 2000 , Davis et al. 2000 ), also showed an

Article Type:
Review Article
DOI:
https://doi.org/10.1677/joe.1.07000
Volume/Issue:
Volume 191: Issue 3
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Tsukasa Nozu Department of Regional Medicine and Education, Asahikawa Medical University, Asahikawa, Hokkaido, Japan

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Saori Miyagishi Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Hokkaido, Japan

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Rintaro Nozu Department of Regional Medicine and Education, Asahikawa Medical University, Asahikawa, Hokkaido, Japan

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Kaoru Takakusaki Research Center for Brain Function and Medical Engineering, Asahikawa Medical University, Asahikawa, Hokkaido, Japan

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Toshikatsu Okumura Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
Department of General Medicine, Asahikawa Medical University, Asahikawa, Hokkaido, Japan

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colonic functional changes including visceral hypersensitivity have been shown. Colorectal distention-induced visceral hyperalgesia or intraperitoneal CRF-induced defecation was blocked by peripheral administration of urocortin 2 ( Million et al. 2006

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-18-0441
Volume/Issue:
Volume 239: Issue 2
Free access
Carmen Corciulo Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Julia M Scheffler Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Piotr Humeniuk Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Alicia Del Carpio Pons Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Alexandra Stubelius Division of Chemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

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Ula Von Mentzer Division of Chemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden

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Christina Drevinge Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Aidan Barrett Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Sofia Wüstenhagen Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Matti Poutanen Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Institute of Biomedicine, Research Centre for Integrative Physiology and Pharmacology, Turku Center for Disease Modeling, University of Turku, Turku, Finland

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Claes Ohlsson Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Department of Drug Treatment, Sahlgrenska University Hospital, Gothenburg, Sweden

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Marie K Lagerquist Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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Ulrika Islander Centre for Bone and Arthritis Research, Department of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden
Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

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replacement for 2 weeks, which was also associated with lower pain sensitivity of the OA paw. OVX has previously been associated with inactivity in mice and treatment with E2 stimulated movement and reduced hyperalgesia ( Gorzek et al. 2007 , Sanoja

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-22-0032
Volume/Issue:
Volume 255: Issue 2
Open access
Marcello Maggiolini
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Didier Picard Department of Pharmaco-Biology, Département de Biologie Cellulaire, University of Calabria, 87030 Rende, Italy

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), and mechanical hyperalgesia in nociceptive neurons of rat dorsal root ganglia ( Kuhn et al . 2008 ). Furthermore, there is evidence for additional functions in the hypothalamus as the control of energy homeostasis may involve GPR30 ( Qiu et al . 2006

Article Type:
Research Article
DOI:
https://doi.org/10.1677/JOE-09-0242
Volume/Issue:
Volume 204: Issue 2
Free access
Silvana Y Romero-Zerbo Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Alex Rafacho Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Adenis Díaz-Arteaga Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Juan Suárez Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Ivan Quesada Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Mónica Imbernon Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Ruth A Ross Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Carlos Dieguez Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Fernando Rodríguez de Fonseca Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Rubén Nogueiras Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Ángel Nadal Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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Francisco J Bermúdez-Silva Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain
Fundación IMABIS, Instituto de Bioingeniería and CIBER de Diabetes y Enfermedades Metabólicas asociadas (CIBERDEM), Department of Physiology, CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn), Institute of Medical Sciences, Neurocentre Magendie, Hospital Carlos Haya de Málaga, Laboratorio de Medicina Regenerativa, Pabellón de Gobierno, sótano, Avenida Carlos Haya 82, 29010 Málaga, Spain

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areas such as the hypothalamus and also in several peripheral tissues involved in energy homeostasis ( Ryberg et al . 2007 ). Recent data have shown that the GPR55 receptor has a role in mechanical hyperalgesia associated with inflammatory and

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-11-0166
Volume/Issue:
Volume 211: Issue 2
Free access
Ladan Eshkevari
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Eva Permaul School of Nursing and Health Studies, Georgetown University Medical Center, USA Departments of Histopathology, Pharmacology and Physiology, Georgetown University Medical Center, 421 St Mary's Hall, 3700 Reservoir Road NW, Washington, District of Columbia 20007

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Susan E Mulroney School of Nursing and Health Studies, Georgetown University Medical Center, USA Departments of Histopathology, Pharmacology and Physiology, Georgetown University Medical Center, 421 St Mary's Hall, 3700 Reservoir Road NW, Washington, District of Columbia 20007

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A parametric study of electroacupuncture on persistent hyperalgesia and Fos protein expression in rats . Brain Research 1020 18 – 29 . ( doi:10.1016/j.brainres.2004.01.092 ) Li Z 2003 In Acupuncture Experimental Science , p 329. China Press of

Article Type:
Research Article
DOI:
https://doi.org/10.1530/JOE-12-0404
Volume/Issue:
Volume 217: Issue 1
Free access
Jane A Mitchell Cardiothoracic Pharmacology, Unit of Critical Care Medicine, Cardiac Medicine, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK

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Mark J Paul-Clark Cardiothoracic Pharmacology, Unit of Critical Care Medicine, Cardiac Medicine, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK

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Graham W Clarke Cardiothoracic Pharmacology, Unit of Critical Care Medicine, Cardiac Medicine, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK

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Shaun K McMaster Cardiothoracic Pharmacology, Unit of Critical Care Medicine, Cardiac Medicine, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK

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Neil Cartwright Cardiothoracic Pharmacology, Unit of Critical Care Medicine, Cardiac Medicine, Royal Brompton Hospital, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK

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chronic lung disease. Clinical Science 109 125 –133. Cunha JM , Cunha FQ, Poole S & Ferreira SH 2000 Cytokine-mediated inflammatory hyperalgesia limited by interleukin-1 receptor antagonist. British Journal of

Article Type:
Review Article
DOI:
https://doi.org/10.1677/JOE-07-0067
Volume/Issue:
Volume 193: Issue 3
Free access