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Jing Lu Department of OB/GYN, Department of OB/GYN, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, Illinois 60201, USA
Department of OB/GYN, Department of OB/GYN, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, Illinois 60201, USA

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Joshua Reese Department of OB/GYN, Department of OB/GYN, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, Illinois 60201, USA

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Ying Zhou Department of OB/GYN, Department of OB/GYN, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, Illinois 60201, USA

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Emmet Hirsch Department of OB/GYN, Department of OB/GYN, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, Illinois 60201, USA
Department of OB/GYN, Department of OB/GYN, NorthShore University HealthSystem, 2650 Ridge Avenue, Evanston, Illinois 60201, USA

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, in the mammary gland ( Santos et al . 2009 ). Feng et al . (2014) demonstrated diminished progesterone receptor membrane component 1 (PGRMC1) at the rupture site among preterm prelabor rupture of membranes (PPROM) subjects compared with preterm

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C Dosiou
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A E Hamilton Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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Y Pang Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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M T Overgaard Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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S Tulac Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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J Dong Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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P Thomas Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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L C Giudice Division of Endocrinology and Metabolism, Department of Obstetrics, University of Texas at Austin Marine Science Institute, Department of Medicine, Stanford University, Stanford, California 94305, USA

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glucocorticoid receptor ( Kontula et al . 1983 ), voltage-gated and Ca 2+ -activated K + channels ( Ehring et al . 1998 ), or another yet unidentified membrane delimited mechanism ( Gamberucci et al . 2004 ). Recently, a novel membrane progesterone receptor

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S Jang Department of Biological Science and the Institute for Basic Science, Sungkyunkwan University, Suwon, 440-746, Korea

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L S H Yi Department of Biological Science and the Institute for Basic Science, Sungkyunkwan University, Suwon, 440-746, Korea

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. 1999 , Patrat et al. 2000 , Somanath et al. 2000 , Jang & Yi 2002 ), which strongly implies that progesterone exerts its effect on mammalian spermatozoa non-genomically via a still unidentified membrane-bound progesterone receptor (mPR). Although

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Joseph Aizen Marine Science Institute, The University of Texas at Austin, 750 Channel View Drive, Port Aransas, Texas 78373, USA

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Peter Thomas Marine Science Institute, The University of Texas at Austin, 750 Channel View Drive, Port Aransas, Texas 78373, USA

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Introduction The single transmembrane protein progesterone receptor membrane component 1 (PGRMC1) is a 25–28 kDa protein that possesses a cytochrome b -like heme-binding domain and belongs to the membrane-associated progesterone receptor (MAPR

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Jorge Diaz Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and
Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Evelyn Aranda Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Soledad Henriquez Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Marisol Quezada Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Estefanía Espinoza Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Maria Loreto Bravo Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Bárbara Oliva Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Soledad Lange Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Manuel Villalon Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Marius Jones Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Jan J Brosens Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Sumie Kato Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and
Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Mauricio A Cuello Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Todd P Knutson Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Carol A Lange Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Lisette Leyton Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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Gareth I Owen Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and
Departamento de Fisiología, Departamento de Ginecología, Clinical Sciences Research Laboratories, Departments of Medicine and Pharmacology, Centro de Estudios Moleculares de la Célula (CEMC), Biomedical Research Consortium (BMRC) Chile, Facultad de Ciencias Biológicas and

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, progestagenic compounds use the progesterone receptor (PR). Post-translational modifications such as sumoylation and phosphorylation have been shown to alter PR transcriptional activity. Phosphorylation of PR Ser-294 augments PR degradation by the 26S proteasome

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Richard Hanna Department of Biology, East Carolina University, 1000 E. 5th Street, Greenville, North Carolina 27858-4553, USA
Marine Science Institute, University of Texas at Austin, 750 Channelview Drive, Port Aransas, Texas 78373, USA

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Yefei Pang Department of Biology, East Carolina University, 1000 E. 5th Street, Greenville, North Carolina 27858-4553, USA
Marine Science Institute, University of Texas at Austin, 750 Channelview Drive, Port Aransas, Texas 78373, USA

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Peter Thomas Department of Biology, East Carolina University, 1000 E. 5th Street, Greenville, North Carolina 27858-4553, USA
Marine Science Institute, University of Texas at Austin, 750 Channelview Drive, Port Aransas, Texas 78373, USA

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Yong Zhu Department of Biology, East Carolina University, 1000 E. 5th Street, Greenville, North Carolina 27858-4553, USA
Marine Science Institute, University of Texas at Austin, 750 Channelview Drive, Port Aransas, Texas 78373, USA

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Research 38 2434 –2437. Karteris E , Zervou S, Pang Y, Dong J, Hillhouse EW, Randeva HS & Thomas P 2006 Progesterone signaling in human myometrium through two novel membrane G protein coupled receptors: potential role in

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M S Fernandes Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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V Pierron Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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D Michalovich Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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S Astle Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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S Thornton Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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H Peltoketo Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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E W-F Lam Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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B Gellersen Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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I Huhtaniemi Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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J Allen Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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J J Brosens Institute of Reproductive and Developmental Biology, Wolfson & Weston Research Centre for Family Health, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Inpharmatica Ltd, London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK
Biomedical Research Institute, Department of Biological Sciences, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
Cancer Research-UK Labs and Section of Cancer Cell Biology, Department of Cancer Medicine, Imperial College London, Hammersmith Hospital, London W12 0NN, UK
Endokrinologikum Hamburg, Falkenried 88, 20251 Hamburg, Germany

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effects are thought to be initiated at the cell surface by unique membrane receptors, although there is compelling evidence that some of the rapid, post-transcriptional progesterone actions involve activation of ‘classical’ steroid receptors

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Atsuya Tsuru Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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Mikihiro Yoshie Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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Mei Suzuki Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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Hiroki Mochizuki Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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Satoshi Kametaka Division of Biofunctional Sciences, Department of Integrated Health Sciences, Graduate School of Medicine, Nagoya University, Aichi, Japan

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Takako Ohmaru-Nakanishi Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

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Mana Azumi Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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Kazuya Kusama Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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Kiyoko Kato Department of Obstetrics and Gynecology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

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Kazuhiro Tamura Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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forskolin, an activator of adenylate cyclase, promotes trophoblast fusion and production of hCG and P4 in primary CTs and the trophoblast-derived choriocarcinoma cell line BeWo ( Tuckey 2005 ). Progesterone receptor membrane component 1 (PGRMC1) is a

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María Andrea Camilletti Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Alejandra Abeledo-Machado Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Jimena Ferraris Instituto de Investigaciones Biomédicas, Facultad de Medicina, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina

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Pablo A Pérez Centro de Microscopia Electrónica, Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Facultad de Ciencias Medicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Erika Y Faraoni Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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Daniel Pisera Instituto de Investigaciones Biomédicas, Facultad de Medicina, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina

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Silvina Gutierrez Centro de Microscopia Electrónica, Instituto de Investigaciones en Ciencias de la Salud (INICSA-CONICET), Facultad de Ciencias Medicas, Universidad Nacional de Córdoba, Córdoba, Argentina

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Graciela Díaz-Torga Instituto de Biología y Medicina Experimental, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina

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the cell surface through binding to membrane estrogen receptors ( Kelly & Levin 2001 , Levin & Hammes 2016 ). Although it was demonstrated that membrane-initiated signaling could be mediated by the classic receptors ERα and ERβ trafficked to the cell

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José E Sánchez-Criado Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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José C Garrido-Gracia Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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Carmina Bellido Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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Rafaela Aguilar Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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Pedro Guelmes Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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Pedro Abreu Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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Rafael Alonso Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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Inmaculada Barranco Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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Yolanda Millán Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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Juana Martín de las Mulas Department of Cell Biology, Physiology and Immunology, University of Córdoba, Avda. Menendez Pidal s/n, 14004 Córdoba, Spain
Department of Physiology, University of La Laguna, La Laguna, Spain
Department of Comparative Pathology, University of Córdoba, Córdoba, Spain

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-induced upregulation of progesterone receptor (PR) in gonadotropes ( Turgeon & Waring 1992 , Sánchez-Criado et al. 2002 , Bellido et al. 2003 ). Activation of the complete oestrogen receptor (ER) orchestra after 3-day administration of oestrogen in rats 2 weeks

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