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ascertain whether the increase in muscle growth was due to increased numbers of myofibres during development (myofibre hyperplasia) and/or hypertrophy, we counted and measured the minimal diameter of each myofibre within transverse sections collected from
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-natal life ( Beilharz et al. 1992 ). This is consistent with IGF1 acting to increase hypertrophy of muscle fibres rather than regulating hyperplasia. In contrast, reduced abundance, or absence of myostatin increases hyperplasia of myofibres ( Hennebry et