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East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
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Human Performance Laboratory, College of Health and Human Performance, East Carolina University, Greenville, North Carolina, USA
Department of Kinesiology, East Carolina University, Greenville, North Carolina, USA
Department of Physiology, East Carolina University, Greenville, North Carolina, USA
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Introduction Obesity is a major risk factor for type 2 diabetes (T2D) ( Kopelman 2000 ) and an important determinant of cardiovascular disease ( Sharma 2003 ); thus, effective approaches for treating obesity and diabetes are needed. Vertical
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AP-HP Hôpital Pitié-Salpêtrière-Charles Foix, Nutrition Department, Paris, France
AP-HP Hôpital Pitié-Salpêtrière-Charles Foix, Diabetology-Metabolism Department, Paris, France
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AP-HP Hôpital Pitié-Salpêtrière-Charles Foix, Nutrition Department, Paris, France
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. T2D is one of the numerous co-morbidities associated with obesity as well as cardiovascular diseases ( Stahel et al. 2020 ). The duration and the amplitude of the postprandial peak of circulating triglyceride (TG) rich lipoproteins (TRL) from
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Introduction Obesity-associated insulin resistance (IR) is characterized by both hyperinsulinemia and hyperglucagonemia and is a key risk factor for the development of type 2 diabetes (T2DM). Although abnormalities in insulin action have been
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Background Within the current global crisis of obesity (BMI ≥30 kg/m 2 ), women of reproductive age represent a group with the steepest rises in obesity rates over recent decades ( NCD Risk Factor Collaboration 2016 ). In the United Kingdom
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Introduction Hormonal disturbance, in either secretion amount or function, often occurs in parallel with impairment of glucose/lipid/protein metabolism in obesity. Two pivotal hormones, insulin and growth hormone (GH), which synergistically
East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
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East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
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East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
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East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
Human Performance Laboratory, Collage of Human Performance and Health, East Carolina University, Greenville, North Carolina, USA
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East Carolina Diabetes and Obesity Institute, East Carolina University, Greenville, North Carolina, USA
Human Performance Laboratory, Collage of Human Performance and Health, East Carolina University, Greenville, North Carolina, USA
Department of Physiology, East Carolina University, Greenville, North Carolina, USA
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Introduction Obesity is reaching epidemic proportions in North America, affecting American society with increased morbidity and mortality as well as economic cost ( Kopelman 2000 ). Obesity is usually associated with defects of energy intake
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Introduction By 2030, 51% of the US population will be obese, and 10% of Americans will have a BMI over 40 kg/m 2 if current trends persist ( Finkelstein et al. 2012 ). Prevention or reducing body weight is a critical factor in controlling
German Center for Diabetes Research (DZD), Neuherberg, Germany
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German Center for Diabetes Research (DZD), Neuherberg, Germany
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German Center for Diabetes Research (DZD), Neuherberg, Germany
Division of Metabolic Diseases, Technische Universität, Munich, Germany
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German Center for Diabetes Research (DZD), Neuherberg, Germany
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Introduction Obesity is a devastating condition of pandemic dimensions. In 2015, there were 107.7 million obese children and 603.7 million obese adults worldwide ( Afshin et al. 2017 ), and this number is expected to rise. Overweight and
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Introduction In the past two decades, the world has seen a sustained increase in obesity, and the levels of overweight and obese persons worldwide have reached epidemic proportions ( Finucane et al . 2011 ). It is well established that obesity
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Department of Physiology, Medical College of Georgia at Augusta University (formerly Georgia Regents University), Augusta, Georgia, USA
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It is well known that obesity is associated with a number of metabolic end organ dysfunctions, including hypertension. However, less well understood is the mechanism by which obesity leads to elevated blood pressure. Various hypotheses have