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Shiping Su, Xiaoxia Sun, Xiuhong Zhou, Fuigui Fang and Yunsheng Li

; two slices per hypothalamic nuclei). * P <0.05, ** P <0.01. Discussion GnRH and thymulin are the two keys signaling molecules that link the reproductive axis and the immune axis. Immunization against GnRH is an effective method of limiting reproduction

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Mohammad Reza Safarinejad, Kamran Azma and Ali Asgar Kolahi

running cycles can be collected. Treadmills have therefore been used in many experimental studies. In this study, we addressed the effects of prolonged high-intensity treadmill running on semen quality, reproductive hormones, and HPT axis. Materials and

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H. F. Urbanski, M. M. Fahy and P. M. Collins

ABSTRACT

The influence of excitatory amino acids (EAAs) on reproductive neuroendocrine function was investigated in adult male Syrian hamsters of the LSH/Ss Lak strain. Before the study, the animals were maintained in a sexually regressed condition, under short days (SD) and subsequently were either transferred to long days (LD) or kept under SD, for a further 4 weeks. In the former group, photostimulation produced a predictable elevation in the hypophysial contents and serum concentrations of FSH and LH. This was accompanied by an increase in testicular size, an elevation in serum testosterone levels and an increase in spermatogenic activity; the SD hamsters remained sexually quiescent throughout the study. In contrast, SD hamsters that were given daily injections of the EAA agonist, N-methyl-d,l-aspartate (NMA: 50 mg/kg body weight, s.c.), showed stimulatory responses that were generally even more pronounced than those shown by the LD group. Surprisingly, an identical NMA treatment paradigm failed to cause a similar activation of the reproductive axis in LD hamsters that were given daily afternoon injections of melatonin (25 μg, s.c), even though the inhibitory effect of this melatonin treatment is generally regarded as being comparable with that produced by exposure to SD. Although EAAs can acutely stimulate the neurocircuitry that controls LH-releasing hormone secretion, the present findings suggest that EAAs might also exert a long-term stimulatory action by acting further upstream in the photoneuroendocrine pathway.

Journal of Endocrinology (1993) 137, 247–252

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Christopher J Scott, Jessica L Rose, Allan J Gunn and Briony M McGrath

://doi.org/10.1111/j.1365-2826.2010.02022.x ) 20456610 Caraty A Decourt C Briant C Beltramo M 2012 Kisspeptins and the reproductive axis: potential applications to manage reproduction in farm animals . Domestic Animal Endocrinology 43 95 – 102

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Fazal Wahab, Ikram Ullah Khan, Ignacio Rodriguez Polo, Hira Zubair, Charis Drummer, Muhammad Shahab and Rüdiger Behr

Introduction The gonadal function is controlled by a complex interaction of regulatory signals, involving hypothalamus, pituitary and the gonads themselves. Altogether, they form the reproductive axis (a.k.a. the hypothalamic

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Edouard G A Mills, Waljit S Dhillo and Alexander N Comninos

emerging roles in its ability to integrate the hypothalamic–pituitary–gonadal (HPG) reproductive axis with appropriate reproductive behaviours. In this review, we critically appraise the current literature regarding kisspeptin and its control of

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Anna Fodor, Ottó Pintér, Ágnes Domokos, Kristina Langnaese, István Barna, Mario Engelmann and Dóra Zelena

di/di rats (‘genotype’בreproductive state’: F (1,36) =5.31, P <0.05). There was no significant difference in thymus mass between the control and lactating females or di/+ or di/di rats ( Fig. 1 D). HPA axis Crh mRNA levels in the PVN were

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Anne M Houbrechts, Jolien Van houcke and Veerle M Darras

compensatory reaction to the low intra-testicular 11-KT levels in order to stimulate the reproductive axis. This is comparable to findings in ar − / − -mutant zebrafish and ARKO mice, displaying upregulated expression levels of steroidogenic genes such

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H Kadokawa, M Matsui, K Hayashi, N Matsunaga, C Kawashima, T Shimizu, K Kida and A Miyamoto

). However, the molecular and cellular mechanisms linking the reproductive axis and somatotropic axis at the levels of the brain and pituitary during puberty still remain incompletely understood. The fact that the kisspeptin–GPR54 system has an important role

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Tabata M Bohlen, Thais T Zampieri, Isadora C Furigo, Pryscila D S Teixeira, Edward O List, John J Kopchick, Jose Donato Jr and Renata Frazao

corresponded to the average age of first estrus ( Silveira et al. 2017 , Bohlen et al. 2018 ), were collected. The hypothalamic mRNA expression of neuropeptides and receptors involved in the regulation of reproductive axis and energy balance were assessed