Search Results
Stephen P Ashcroft
Stephen P Ashcroft
School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, UK
MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, Clinical, Metabolic and Molecular Physiology, University of Nottingham, Royal Derby Hospital Centre, Derby, UK
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
Search for other papers by Stephen P Ashcroft in
Google Scholar
PubMed
MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, Clinical, Metabolic and Molecular Physiology, University of Nottingham, Royal Derby Hospital Centre, Derby, UK
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
Search for other papers by Stephen P Ashcroft in
Google Scholar
PubMed
Gareth Fletcher
Gareth Fletcher
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
Search for other papers by Gareth Fletcher in
Google Scholar
PubMed
Search for other papers by Gareth Fletcher in
Google Scholar
PubMed
Ashleigh M Philp
Ashleigh M Philp
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia
Search for other papers by Ashleigh M Philp in
Google Scholar
PubMed
St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia
Search for other papers by Ashleigh M Philp in
Google Scholar
PubMed
Carl Jenkinson
Carl Jenkinson
Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK
ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia
Search for other papers by Carl Jenkinson in
Google Scholar
PubMed
ANZAC Research Institute, University of Sydney, Sydney, New South Wales, Australia
Search for other papers by Carl Jenkinson in
Google Scholar
PubMed
Shatarupa Das
Shatarupa Das
Centenary Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
UTS Centenary Centre for Inflammation, University Technology Sydney, New South Wales, Australia
Search for other papers by Shatarupa Das in
Google Scholar
PubMed
UTS Centenary Centre for Inflammation, University Technology Sydney, New South Wales, Australia
Search for other papers by Shatarupa Das in
Google Scholar
PubMed
Philip M Hansbro
Philip M Hansbro
Centenary Institute, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia
UTS Centenary Centre for Inflammation, University Technology Sydney, New South Wales, Australia
Search for other papers by Philip M Hansbro in
Google Scholar
PubMed
UTS Centenary Centre for Inflammation, University Technology Sydney, New South Wales, Australia
Search for other papers by Philip M Hansbro in
Google Scholar
PubMed
Philip J Atherton
Philip J Atherton
MRC-Versus Arthritis Centre for Musculoskeletal Ageing Research, Clinical, Metabolic and Molecular Physiology, University of Nottingham, Royal Derby Hospital Centre, Derby, UK
Search for other papers by Philip J Atherton in
Google Scholar
PubMed
Search for other papers by Philip J Atherton in
Google Scholar
PubMed
Andrew Philp
Andrew Philp
Mitochondrial Metabolism and Ageing Laboratory, Garvan Institute of Medical Research, Sydney, New South Wales, Australia
St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia
Search for other papers by Andrew Philp in
Google Scholar
PubMed
St Vincent’s Clinical School, UNSW Medicine, UNSW Sydney, New South Wales, Australia
Search for other papers by Andrew Philp in
Google Scholar
PubMed
Introduction Vitamin D deficiency, characterised by serum 25-hydroxyvitamin D (25(OH)D) levels of < 50 nmol/L, remains prevalent across both Europe and the United States of America ( Forrest & Stuhldreher 2011 , Cashman et al. 2016
J A Tamblyn
J A Tamblyn
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
Search for other papers by J A Tamblyn in
Google Scholar
PubMed
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
Search for other papers by J A Tamblyn in
Google Scholar
PubMed
M Hewison
M Hewison
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
Search for other papers by M Hewison in
Google Scholar
PubMed
Search for other papers by M Hewison in
Google Scholar
PubMed
C L Wagner
C L Wagner
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
Search for other papers by C L Wagner in
Google Scholar
PubMed
Search for other papers by C L Wagner in
Google Scholar
PubMed
J N Bulmer
J N Bulmer
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
Search for other papers by J N Bulmer in
Google Scholar
PubMed
Search for other papers by J N Bulmer in
Google Scholar
PubMed
M D Kilby
M D Kilby
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
Search for other papers by M D Kilby in
Google Scholar
PubMed
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
College of Medical and Dental Sciences, College of Medical and Dental Sciences, Departments of Pediatrics, Reproductive and Vascular Biology Group, Fetal Medicine Centre, Centre for Women's and Children's Health
Search for other papers by M D Kilby in
Google Scholar
PubMed
of vitamin D at the maternal–fetal interface. Illustration of both the innate and adaptive leukocyte decidual subsets with the potential capacity for intrinsic 1,25-dihydroxyvitamin D (1,25(OH) 2 D) synthesis from 25-hydroxyvitamin D (25OHD
Daniela Leite de Oliveira
Daniela Leite de Oliveira
Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil
Search for other papers by Daniela Leite de Oliveira in
Google Scholar
PubMed
Search for other papers by Daniela Leite de Oliveira in
Google Scholar
PubMed
Camila Hirotsu
Camila Hirotsu
Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil
Search for other papers by Camila Hirotsu in
Google Scholar
PubMed
Search for other papers by Camila Hirotsu in
Google Scholar
PubMed
Sergio Tufik
Sergio Tufik
Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil
Search for other papers by Sergio Tufik in
Google Scholar
PubMed
Search for other papers by Sergio Tufik in
Google Scholar
PubMed
Monica Levy Andersen
Monica Levy Andersen
Department of Psychobiology, Universidade Federal de São Paulo, São Paulo, Brazil
Search for other papers by Monica Levy Andersen in
Google Scholar
PubMed
Search for other papers by Monica Levy Andersen in
Google Scholar
PubMed
Introduction The musculoskeletal benefits of vitamin D are widely known: they promote the calcification of bone matrix and increase the absorption of calcium and phosphate in the intestine. Vitamin D deficiency can cause rickets in children
Rene F Chun
Rene F Chun
Department of Orthopaedic Surgery, Molecular Biology Institute, David Geffen School of Medicine, UCLA, 615 Charles E Young Drive South, Los Angeles, California 90095, USA
Search for other papers by Rene F Chun in
Google Scholar
PubMed
Search for other papers by Rene F Chun in
Google Scholar
PubMed
John S Adams
John S Adams
Department of Orthopaedic Surgery, Molecular Biology Institute, David Geffen School of Medicine, UCLA, 615 Charles E Young Drive South, Los Angeles, California 90095, USA
Department of Orthopaedic Surgery, Molecular Biology Institute, David Geffen School of Medicine, UCLA, 615 Charles E Young Drive South, Los Angeles, California 90095, USA
Search for other papers by John S Adams in
Google Scholar
PubMed
Department of Orthopaedic Surgery, Molecular Biology Institute, David Geffen School of Medicine, UCLA, 615 Charles E Young Drive South, Los Angeles, California 90095, USA
Search for other papers by John S Adams in
Google Scholar
PubMed
Martin Hewison
Martin Hewison
Department of Orthopaedic Surgery, Molecular Biology Institute, David Geffen School of Medicine, UCLA, 615 Charles E Young Drive South, Los Angeles, California 90095, USA
Department of Orthopaedic Surgery, Molecular Biology Institute, David Geffen School of Medicine, UCLA, 615 Charles E Young Drive South, Los Angeles, California 90095, USA
Search for other papers by Martin Hewison in
Google Scholar
PubMed
Department of Orthopaedic Surgery, Molecular Biology Institute, David Geffen School of Medicine, UCLA, 615 Charles E Young Drive South, Los Angeles, California 90095, USA
Search for other papers by Martin Hewison in
Google Scholar
PubMed
Introduction At the end of 2007, Time magazine listed the ‘Benefits of Vitamin D’ as one of its top ten ‘medical breakthroughs’ of the year. The reason for this they stated has been the recent remarkable increase in studies documenting new actions
Ankana Ganguly
Ankana Ganguly
Institute of Metabolism and Systems Research, The University of Birmingham, Birmingham, UK
Search for other papers by Ankana Ganguly in
Google Scholar
PubMed
Search for other papers by Ankana Ganguly in
Google Scholar
PubMed
Jennifer A Tamblyn
Jennifer A Tamblyn
Institute of Metabolism and Systems Research, The University of Birmingham, Birmingham, UK
Fetal Medicine Centre, Birmingham Women’s NHS Foundation Trust, Birmingham, UK
CEDAM, Birmingham Health Partners, The University of Birmingham, Birmingham, UK
Search for other papers by Jennifer A Tamblyn in
Google Scholar
PubMed
Fetal Medicine Centre, Birmingham Women’s NHS Foundation Trust, Birmingham, UK
CEDAM, Birmingham Health Partners, The University of Birmingham, Birmingham, UK
Search for other papers by Jennifer A Tamblyn in
Google Scholar
PubMed
Sarah Finn-Sell
Sarah Finn-Sell
Division of Developmental Biology and Medicine, Maternal and Fetal Health Research Centre, School of Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
Search for other papers by Sarah Finn-Sell in
Google Scholar
PubMed
Search for other papers by Sarah Finn-Sell in
Google Scholar
PubMed
Shiao-Y Chan
Shiao-Y Chan
Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
Search for other papers by Shiao-Y Chan in
Google Scholar
PubMed
Search for other papers by Shiao-Y Chan in
Google Scholar
PubMed
Melissa Westwood
Melissa Westwood
Division of Developmental Biology and Medicine, Maternal and Fetal Health Research Centre, School of Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
Search for other papers by Melissa Westwood in
Google Scholar
PubMed
Search for other papers by Melissa Westwood in
Google Scholar
PubMed
Janesh Gupta
Janesh Gupta
Institute of Metabolism and Systems Research, The University of Birmingham, Birmingham, UK
Fetal Medicine Centre, Birmingham Women’s NHS Foundation Trust, Birmingham, UK
Search for other papers by Janesh Gupta in
Google Scholar
PubMed
Fetal Medicine Centre, Birmingham Women’s NHS Foundation Trust, Birmingham, UK
Search for other papers by Janesh Gupta in
Google Scholar
PubMed
Mark D Kilby
Mark D Kilby
Institute of Metabolism and Systems Research, The University of Birmingham, Birmingham, UK
Fetal Medicine Centre, Birmingham Women’s NHS Foundation Trust, Birmingham, UK
Search for other papers by Mark D Kilby in
Google Scholar
PubMed
Fetal Medicine Centre, Birmingham Women’s NHS Foundation Trust, Birmingham, UK
Search for other papers by Mark D Kilby in
Google Scholar
PubMed
Stephane R Gross
Stephane R Gross
School of Life and Health Sciences, Aston University, Birmingham, UK
Search for other papers by Stephane R Gross in
Google Scholar
PubMed
Search for other papers by Stephane R Gross in
Google Scholar
PubMed
Martin Hewison
Martin Hewison
Institute of Metabolism and Systems Research, The University of Birmingham, Birmingham, UK
CEDAM, Birmingham Health Partners, The University of Birmingham, Birmingham, UK
Search for other papers by Martin Hewison in
Google Scholar
PubMed
CEDAM, Birmingham Health Partners, The University of Birmingham, Birmingham, UK
Search for other papers by Martin Hewison in
Google Scholar
PubMed
regulation of trophoblast invasion have been well documented ( Menkhorst et al . 2016 ). The aim of the current review is to provide an overview of these early events in placental development, with particular emphasis on the potential role of vitamin D as a
Nele Cielen
Nele Cielen
Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, KULeuven, Leuven, Belgium
Search for other papers by Nele Cielen in
Google Scholar
PubMed
Search for other papers by Nele Cielen in
Google Scholar
PubMed
Nele Heulens
Nele Heulens
Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, KULeuven, Leuven, Belgium
Search for other papers by Nele Heulens in
Google Scholar
PubMed
Search for other papers by Nele Heulens in
Google Scholar
PubMed
Karen Maes
Karen Maes
Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, KULeuven, Leuven, Belgium
Search for other papers by Karen Maes in
Google Scholar
PubMed
Search for other papers by Karen Maes in
Google Scholar
PubMed
Geert Carmeliet
Geert Carmeliet
Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, KULeuven, Leuven, Belgium
Search for other papers by Geert Carmeliet in
Google Scholar
PubMed
Search for other papers by Geert Carmeliet in
Google Scholar
PubMed
Chantal Mathieu
Chantal Mathieu
Laboratory of Clinical and Experimental Endocrinology, Department of Clinical and Experimental Medicine, KULeuven, Leuven, Belgium
Search for other papers by Chantal Mathieu in
Google Scholar
PubMed
Search for other papers by Chantal Mathieu in
Google Scholar
PubMed
Wim Janssens
Wim Janssens
Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, KULeuven, Leuven, Belgium
Search for other papers by Wim Janssens in
Google Scholar
PubMed
Search for other papers by Wim Janssens in
Google Scholar
PubMed
Ghislaine Gayan-Ramirez
Ghislaine Gayan-Ramirez
Laboratory of Respiratory Diseases, Department of Clinical and Experimental Medicine, KULeuven, Leuven, Belgium
Search for other papers by Ghislaine Gayan-Ramirez in
Google Scholar
PubMed
Search for other papers by Ghislaine Gayan-Ramirez in
Google Scholar
PubMed
addition to smoking, physical inactivity, oxidative stress, and systemic inflammation, other factors such as vitamin D deficiency may contribute to the large variability in the prevalence and severity of skeletal muscle dysfunction in COPD ( Maltais et al
Nathanael J Yates
Nathanael J Yates
School of Human Sciences, The University of Western Australia, Perth, Australia
Search for other papers by Nathanael J Yates in
Google Scholar
PubMed
Search for other papers by Nathanael J Yates in
Google Scholar
PubMed
Dijana Tesic
Dijana Tesic
School of Human Sciences, The University of Western Australia, Perth, Australia
Search for other papers by Dijana Tesic in
Google Scholar
PubMed
Search for other papers by Dijana Tesic in
Google Scholar
PubMed
Kirk W Feindel
Kirk W Feindel
Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, Perth, Australia
Search for other papers by Kirk W Feindel in
Google Scholar
PubMed
Search for other papers by Kirk W Feindel in
Google Scholar
PubMed
Jeremy T Smith
Jeremy T Smith
School of Human Sciences, The University of Western Australia, Perth, Australia
Search for other papers by Jeremy T Smith in
Google Scholar
PubMed
Search for other papers by Jeremy T Smith in
Google Scholar
PubMed
Michael W Clarke
Michael W Clarke
Metabolomics Australia, Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, Perth, Australia
Search for other papers by Michael W Clarke in
Google Scholar
PubMed
Search for other papers by Michael W Clarke in
Google Scholar
PubMed
Celeste Wale
Celeste Wale
School of Human Sciences, The University of Western Australia, Perth, Australia
Search for other papers by Celeste Wale in
Google Scholar
PubMed
Search for other papers by Celeste Wale in
Google Scholar
PubMed
Rachael C Crew
Rachael C Crew
School of Human Sciences, The University of Western Australia, Perth, Australia
Search for other papers by Rachael C Crew in
Google Scholar
PubMed
Search for other papers by Rachael C Crew in
Google Scholar
PubMed
Michaela D Wharfe
Michaela D Wharfe
School of Human Sciences, The University of Western Australia, Perth, Australia
Search for other papers by Michaela D Wharfe in
Google Scholar
PubMed
Search for other papers by Michaela D Wharfe in
Google Scholar
PubMed
Andrew J O Whitehouse
Andrew J O Whitehouse
Telethon Kids Institute, The University of Western Australia, Perth, Australia
Search for other papers by Andrew J O Whitehouse in
Google Scholar
PubMed
Search for other papers by Andrew J O Whitehouse in
Google Scholar
PubMed
Caitlin S Wyrwoll
Caitlin S Wyrwoll
School of Human Sciences, The University of Western Australia, Perth, Australia
Search for other papers by Caitlin S Wyrwoll in
Google Scholar
PubMed
Search for other papers by Caitlin S Wyrwoll in
Google Scholar
PubMed
Introduction The quality of early life environment is a powerful determinant of adult health outcomes, including brain function ( Cottrell & Seckl 2009 ). The abundant expression of vitamin D receptors within the foetal brain ( Eyles et al
E J Lock
E J Lock
National Institute of Nutrition and Seafood Research, PO Box 2029 Nordnes, N-5817, Bergen, Norway
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by E J Lock in
Google Scholar
PubMed
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by E J Lock in
Google Scholar
PubMed
R Ørnsrud
R Ørnsrud
National Institute of Nutrition and Seafood Research, PO Box 2029 Nordnes, N-5817, Bergen, Norway
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by R Ørnsrud in
Google Scholar
PubMed
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by R Ørnsrud in
Google Scholar
PubMed
L Aksnes
L Aksnes
National Institute of Nutrition and Seafood Research, PO Box 2029 Nordnes, N-5817, Bergen, Norway
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by L Aksnes in
Google Scholar
PubMed
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by L Aksnes in
Google Scholar
PubMed
F A T Spanings
F A T Spanings
National Institute of Nutrition and Seafood Research, PO Box 2029 Nordnes, N-5817, Bergen, Norway
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by F A T Spanings in
Google Scholar
PubMed
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by F A T Spanings in
Google Scholar
PubMed
R Waagbø
R Waagbø
National Institute of Nutrition and Seafood Research, PO Box 2029 Nordnes, N-5817, Bergen, Norway
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by R Waagbø in
Google Scholar
PubMed
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by R Waagbø in
Google Scholar
PubMed
G Flik
G Flik
National Institute of Nutrition and Seafood Research, PO Box 2029 Nordnes, N-5817, Bergen, Norway
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by G Flik in
Google Scholar
PubMed
Department of Animal Physiology, Faculty of Science, Radboud University Nijmegen, Toernooiveld 1 NL-6525ED, Nijmegen, The Netherlands
Division of Pediatrics, Department of Clinical and Molecular Medicine, University of Bergen, Haukeland University Hospital, N-5021, Bergen, Norway
Search for other papers by G Flik in
Google Scholar
PubMed
Introduction The vitamin D endocrine system in vertebrates is a major regulator of calcium and phosphate homeostasis ( Norman et al. 2002 ). Current research focuses on the two vitamin D metabolites 24 R ,25-dihydroxyvitamin D 3
Lauriane Bonnet
Lauriane Bonnet
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
Search for other papers by Lauriane Bonnet in
Google Scholar
PubMed
Search for other papers by Lauriane Bonnet in
Google Scholar
PubMed
Esma Karkeni
Esma Karkeni
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
Search for other papers by Esma Karkeni in
Google Scholar
PubMed
Search for other papers by Esma Karkeni in
Google Scholar
PubMed
Charlène Couturier
Charlène Couturier
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
Search for other papers by Charlène Couturier in
Google Scholar
PubMed
Search for other papers by Charlène Couturier in
Google Scholar
PubMed
Julien Astier
Julien Astier
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
Search for other papers by Julien Astier in
Google Scholar
PubMed
Search for other papers by Julien Astier in
Google Scholar
PubMed
Catherine Defoort
Catherine Defoort
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
CriBioM, Criblage Biologique Marseille, Faculté de Médecine de la Timone, Marseille, France
Search for other papers by Catherine Defoort in
Google Scholar
PubMed
CriBioM, Criblage Biologique Marseille, Faculté de Médecine de la Timone, Marseille, France
Search for other papers by Catherine Defoort in
Google Scholar
PubMed
Ljubica Svilar
Ljubica Svilar
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
CriBioM, Criblage Biologique Marseille, Faculté de Médecine de la Timone, Marseille, France
Search for other papers by Ljubica Svilar in
Google Scholar
PubMed
CriBioM, Criblage Biologique Marseille, Faculté de Médecine de la Timone, Marseille, France
Search for other papers by Ljubica Svilar in
Google Scholar
PubMed
Franck Tourniaire
Franck Tourniaire
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
CriBioM, Criblage Biologique Marseille, Faculté de Médecine de la Timone, Marseille, France
Search for other papers by Franck Tourniaire in
Google Scholar
PubMed
CriBioM, Criblage Biologique Marseille, Faculté de Médecine de la Timone, Marseille, France
Search for other papers by Franck Tourniaire in
Google Scholar
PubMed
Lourdes Mounien
Lourdes Mounien
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
Search for other papers by Lourdes Mounien in
Google Scholar
PubMed
Search for other papers by Lourdes Mounien in
Google Scholar
PubMed
Jean-François Landrier
Jean-François Landrier
Aix-Marseille Université, C2VN, INRAE, INSERM, Marseille, France
CriBioM, Criblage Biologique Marseille, Faculté de Médecine de la Timone, Marseille, France
Search for other papers by Jean-François Landrier in
Google Scholar
PubMed
CriBioM, Criblage Biologique Marseille, Faculté de Médecine de la Timone, Marseille, France
Search for other papers by Jean-François Landrier in
Google Scholar
PubMed
Introduction Low levels of total circulating 25-hydroxy-vitamin D (25(OH)D) are strongly associated with obesity and more specially with increased fat mass and BMI ( Vilarrasa et al. 2007 , Earthman et al. 2012 , Landrier et al. 2016
F H Glorieux
F H Glorieux
Search for other papers by F H Glorieux in
Google Scholar
PubMed
Search for other papers by F H Glorieux in
Google Scholar
PubMed
In 1961, Prader et al. (1961) reported on a new form of vitamin D resistant rickets, which differed from the classic hypophosphatemic type (Albright et al. 1937) by its early onset (within the first year of life), the development of severe hypocalcemia with tetany, moderate hypophosphatemia and hyperaminoaciduria both reflecting secondary hyperparathyroidism, enamel hypoplasia and the complete correction of all clinical and biochemical evidence of rickets (including stunted growth rate) with high daily doses of vitamin D. In the initial report identifying this hereditary form of pseudo-vitamin D deficiency rickets (PDDR), transmission was reported to be autosomal dominant. Later, recessive inheritance was established (Fanconi & Prader 1969). In view of the fact that to maintain health, intake of vitamin D had to be consistently in vast excess of the recommended daily allowance (400 IU), the term 'vitamin D dependency' (VDD) was proposed to describe the new syndrome (Scriver 1970).
In
