The estrogen receptor α-selective agonist propyl pyrazole triol improves glucose tolerance in ob/ob mice: potential molecular mechanisms

in Journal of Endocrinology
Authors:
L LundholmDepartment of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden

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G BryzgalovaDepartment of Molecular Medicine and Surgery, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden

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H GaoDepartment of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden

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N PortwoodDepartment of Molecular Medicine and Surgery, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden

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S FältDepartment of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden

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K D BerndtDepartment of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden

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A DickerDepartment of Medicine, Karolinska Institute, Karolinska University Hospital, Huddinge, Sweden

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D GaluskaDepartment of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

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J R ZierathDepartment of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

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J-Å GustafssonDepartment of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden

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S EfendicDepartment of Molecular Medicine and Surgery, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden

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K Dahlman-WrightDepartment of Biosciences and Nutrition, Karolinska Institute, Huddinge, Sweden

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A KhanDepartment of Molecular Medicine and Surgery, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden

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Correspondence should be addressed to L Lundholm: lovisa.lundholm@su.se
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The authors and journal apologise for an error in the above paper, which appeared in volume 199 part 2, pages 275–286. The error relates to Fig. 10, given on page 283. The corrected composite figure for Fig. 10 is given in full below:

Figure 10
Figure 10

Western blot analysis of Stat3, phosphorylated Stat3 on Tyr705 (Stat3P), and glucose-6-phosphatase (G6p) protein in liver of ob/ob mice treated with vehicle or PPT for 30 days (n = 5 mice/group). (A) Immunoblots for each respective protein showing the results for individual liver samples from the vehicle-treated or PPT-treated mice. (B) Mean ± s.e.m. relative abundance for each respective protein in liver of vehicle-treated (open bar) or PPT-treated (filled bar) ob/ob mice (n = 5 mice/group). P = 0.07, **P < 0.01 for PPT-treated versus vehicle-treated ob/ob mice.

Citation: Journal of Endocrinology 243, 2; 10.1530/JOE-08-0192e

 

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    Figure 10

    Western blot analysis of Stat3, phosphorylated Stat3 on Tyr705 (Stat3P), and glucose-6-phosphatase (G6p) protein in liver of ob/ob mice treated with vehicle or PPT for 30 days (n = 5 mice/group). (A) Immunoblots for each respective protein showing the results for individual liver samples from the vehicle-treated or PPT-treated mice. (B) Mean ± s.e.m. relative abundance for each respective protein in liver of vehicle-treated (open bar) or PPT-treated (filled bar) ob/ob mice (n = 5 mice/group). P = 0.07, **P < 0.01 for PPT-treated versus vehicle-treated ob/ob mice.